Kent Miner

Amgen (United States) — United States

Immunology and Microbiology · Life Sciences

16h-index1.8kcitations21works0.02yr avg
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Research Topics

T-cell and B-cell Immunology(11), Immunotherapy and Immune Responses(8), Immune Cell Function and Interaction(8), Asthma and respiratory diseases(3), Protein Kinase Regulation and GTPase Signaling(2)

Publications21 total

Development of an ICOSL and BAFF bispecific inhibitor AMG 570 for systemic lupus erythematosus treatment.
PubMed·2019· 31 cited
Drug Repurposing: The Anthelmintics Niclosamide and Nitazoxanide Are Potent TMEM16A Antagonists That Fully Bronchodilate Airways
Frontiers in Pharmacology·2019· 132 citedOpen Access
Drug Repurposing: The Anthelmintics Niclosamide and Nitazoxanide are Potent TMEM16A Antagonists that Fully Bronchodilate Airways
2018· 9 citedOpen Access
Discovery and in Vivo Evaluation of Dual PI3Kβ/δ Inhibitors
Journal of Medicinal Chemistry·2012· 49 citedOpen Access
A novel modality of BAFF-specific inhibitor AMG623 peptibody reduces B-cell number and improves outcomes in murine models of autoimmune disease.
PubMed·2012· 47 cited
Murine collagen antibody induced arthritis (CAIA) and primary mouse hepatocyte culture as models to study cytochrome P450 suppression
Biochemical Pharmacology·2012· 16 cited
Part 2: Structure–activity relationship (SAR) investigations of fused pyrazoles as potent, selective and orally available inhibitors of p38α mitogen-activated protein kinase
Bioorganic & Medicinal Chemistry Letters·2010· 18 cited
Part 1: Structure–Activity Relationship (SAR) investigations of fused pyrazoles as potent, selective and orally available inhibitors of p38α mitogen-activated protein kinase
Bioorganic & Medicinal Chemistry Letters·2009· 20 citedOpen Access
Characterization of a new human B7-related protein: B7RP-1 is the ligand to the co-stimulatory protein ICOS
International Immunology·2000· 134 citedOpen Access
Taci Is a Traf-Interacting Receptor for Tall-1, a Tumor Necrosis Factor Family Member Involved in B Cell Regulation
The Journal of Experimental Medicine·2000· 248 citedOpen Access
Severe B cell hyperplasia and autoimmune disease in TALL-1 transgenic mice
Proceedings of the National Academy of Sciences·2000· 572 citedOpen Access
Co-stimulation of antigen-specific CD4 T cells by 4-1BB ligand
European Journal of Immunology·2000· 5 cited
Co-stimulation of antigen-specific CD4 T cells by 4-1BB ligand
European Journal of Immunology·2000· 119 citedOpen Access
Activation of CD4 T Cells by Somatic Transgenesis Induces Generalized Immunity of Uncommitted T Cells and Immunologic Memory
The Journal of Immunology·1999· 13 citedOpen Access
Lymphotoxin alphabeta is expressed on recently activated naive and Th1-like CD4 cells but is down-regulated by IL-4 during Th2 differentiation.
PubMed·1999· 53 cited
Lymphotoxin αβ Is Expressed on Recently Activated Naive and Th1-Like CD4 Cells but Is Down-Regulated by IL-4 During Th2 Differentiation
The Journal of Immunology·1999· 57 citedOpen Access
Generation, persistence, and modulation of Th0 effector cells: role of autocrine IL-4 and IFN-gamma.
PubMed·1998· 68 cited
Generation, Persistence, and Modulation of Th0 Effector Cells: Role of Autocrine IL-4 and IFN-γ
The Journal of Immunology·1998· 58 citedOpen Access
Augmentation of naive, Th1 and Th2 effector CD4 Responses by IL-6, IL-1 and TNF
European Journal of Immunology·1998· 96 cited
Augmentation of naive, Th1 and Th2 effector CD4 Responses by IL-6, IL-1 and TNF
European Journal of Immunology·1998
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Frequent Co-authors

Michael Croft(10), Sanjay D. Khare(4), Xing-Zhong Xia(4), Hailing Hsu(4), John Whoriskey(4), Irene Gramaglia(4), Helen J. McBride(4), Nessa Hawkins(3), John Delaney(3), T. Boone(3), Robin Elliott(3), Kevin Gaida(3), Deanna Mohn(3), Sean B. Joseph(3), Susan McCabe(2), Irina Solovyev(2), Michael J. Kelley(2), William J. Boyle(2), Frances Lee(2), Gang Yu(2)