Sean B. Joseph

Scripps Research Institute — United States

Medicine · Health Sciences

38h-index13.1kcitations87works3.92yr avg
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Research Topics

Cholesterol and Lipid Metabolism(17), Peroxisome Proliferator-Activated Receptors(14), Monoclonal and Polyclonal Antibodies Research(13), Drug Transport and Resistance Mechanisms(12), Cancer, Lipids, and Metabolism(7)

Publications87 total

NK2R signaling governs intestinal lipid mobilization and mucosal inflammation
2025Open Access
A drug repurposing approach reveals targetable epigenetic pathways in Plasmodium vivax hypnozoites
eLife·2025· 1 citedOpen Access
SuFEx-based antitubercular compound irreversibly inhibits Pks13
Nature·2025· 7 cited
Integrating Production and Corrosion Monitoring in Unconventional Environment Getting Conclusive Investigation of Lower Completion Status Unleashing the Full Potential Through Advanced Logging Techniques
2025
Identification of mCMQ069, a novel antimalarial with potential for a single-dose cure and/or 28-day chemoprevention
2024Open Access
Correction to “Discovery of CMX990: A Potent SARS-CoV-2 3CL Protease Inhibitor Bearing a Novel Warhead”
Journal of Medicinal Chemistry·2024Open Access
Author response: A Drug Repurposing Approach Reveals Targetable Epigenetic Pathways in Plasmodium vivax Hypnozoites
2024Open Access
A Drug Repurposing Approach Reveals Targetable Epigenetic Pathways in Plasmodium vivax Hypnozoites
2024· 3 citedOpen Access
A drug repurposing approach reveals targetable epigenetic pathways in Plasmodium vivax hypnozoites
eLife·2024· 2 citedOpen Access
Pharmacological expansion of type 2 alveolar epithelial cells promotes regenerative lower airway repair
Proceedings of the National Academy of Sciences·2024· 15 citedOpen Access
A small molecule MST1/2 inhibitor accelerates murine liver regeneration with improved survival in models of steatohepatitis
PNAS Nexus·2024· 4 citedOpen Access
A Prodrug Strategy to Reposition Atovaquone as a Long-Acting Injectable for Malaria Chemoprotection
2024· 1 citedOpen Access
Discovery of CMX990: A Potent SARS-CoV-2 3CL Protease Inhibitor Bearing a Novel Warhead
Journal of Medicinal Chemistry·2024· 18 citedOpen Access
Discovery of CMX990: A Potent SARS-CoV-2 3CL Protease Inhibitor Bearing a Novel Covalent Warhead
2023· 1 citedOpen Access
Pharmacological YAP activation promotes regenerative repair of cutaneous wounds
Proceedings of the National Academy of Sciences·2023· 35 citedOpen Access
Data from Relative Target Affinities of T-Cell–Dependent Bispecific Antibodies Determine Biodistribution in a Solid Tumor Mouse Model
2023Open Access
Data from Relative Target Affinities of T-Cell–Dependent Bispecific Antibodies Determine Biodistribution in a Solid Tumor Mouse Model
2023Open Access
Supplemental Methods and Figures 1-5 from Relative Target Affinities of T-Cell–Dependent Bispecific Antibodies Determine Biodistribution in a Solid Tumor Mouse Model
2023Open Access
Supplemental Methods and Figures 1-5 from Relative Target Affinities of T-Cell–Dependent Bispecific Antibodies Determine Biodistribution in a Solid Tumor Mouse Model
2023Open Access
A Drug Repurposing Approach Reveals Targetable Epigenetic Pathways in <i>Plasmodium vivax</i> Hypnozoites
2023· 22 citedOpen Access
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Frequent Co-authors

Peter Tontonoz(17), Bryan Laffitte(15), Peter G. Schultz(9), Arnab K. Chatterjee(8), Antonio Castrillo(7), David J. Mangelsdorf(7), Damien C. Wilpitz(5), Robert Walczak(5), Ashley K. Woods(5), Saileta Prabhu(5), Vân Nguyên-Trân(5), Peter A. Edwards(4), Liming Pei(4), Jon L. Collins(4), Badry Bursulaya(4), H. Martin Seidel(4), Peter McNamara(4), Case W. McNamara(4), Matthew S. Tremblay(4), C. Andrew Boswell(4)