John F. Ervin

Duke University — United States

Medicine · Health Sciences

24h-index1.8kcitations55works4.32yr avg
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Research Topics

Alzheimer's disease research and treatments(25), Dementia and Cognitive Impairment Research(12), Parkinson's Disease Mechanisms and Treatments(9), Neurological Disease Mechanisms and Treatments(6), Cholinesterase and Neurodegenerative Diseases(4)

Publications50 total

Markers of leucine‐rich repeat kinase 2 activity are associated with pathological protein aggregation across neurodegenerative diseases
Alzheimer s & Dementia·2025Open Access
LRRK2 kinase-mediated accumulation of lysosome-associated phospho-Rabs in tauopathies and synucleinopathies
UNC Libraries·2025Open Access
LRRK2 kinase-mediated accumulation of lysosome-associated phospho-Rabs in tauopathies and synucleinopathies
Acta Neuropathologica·2025· 4 citedOpen Access
Accumulation of LRRK2-associated phospho-Rab12 degenerative lysosomes in tauopathies
2025Open Access
Performance of Polygenic Risk Scores for Primary Open-Angle Glaucoma in Populations of African Descent
JAMA Ophthalmology·2024· 3 citedOpen Access
Star-shaped TDP-43 inclusions in the oldest-old
Journal of Neuropathology & Experimental Neurology·2024· 1 citedOpen Access
Detection of mild cognitive impairment of Alzheimer’s disease and tauopathy differentiation by phospho‐tau396
Alzheimer s & Dementia·2023Open Access
GABA signaling triggered by TMC-1/Tmc delays neuronal aging by inhibiting the PKC pathway in <i>C. elegans</i>
Science Advances·2022· 16 citedOpen Access
Site-Specific Phospho-Tau Aggregation-Based Biomarker Discovery for AD Diagnosis and Differentiation
ACS Chemical Neuroscience·2022· 20 citedOpen Access
Corpora amylacea are associated with tau burden and cognitive status in Alzheimer’s disease
Acta Neuropathologica Communications·2022· 16 citedOpen Access
Frequency of LATE neuropathologic change across the spectrum of Alzheimer’s disease neuropathology: combined data from 13 community-based or population-based autopsy cohorts
Acta Neuropathologica·2022· 151 citedOpen Access
Neuropathological associations of limbic-predominant age-related TDP-43 encephalopathy neuropathological change (LATE-NC) differ between the oldest-old and younger-old
Acta Neuropathologica·2022· 20 citedOpen Access
Tuberous sclerosis complex is a novel, amyloid-independent tauopathy associated with elevated phosphorylated 3R/4R tau aggregation
Acta Neuropathologica Communications·2022· 13 citedOpen Access
Correction to: Limbic-predominant age-related TDP-43 encephalopathy neuropathological change (LATE-NC) is independently associated with dementia and strongly associated with arteriolosclerosis in the oldest-old
Acta Neuropathologica·2021· 1 citedOpen Access
Limbic-predominant age-related TDP-43 encephalopathy neuropathological change (LATE-NC) is independently associated with dementia and strongly associated with arteriolosclerosis in the oldest-old
Acta Neuropathologica·2021· 34 citedOpen Access
Papillary Glioneuronal Tumor With a Novel GPR37L1-PRKCA Fusion
Journal of Neuropathology & Experimental Neurology·2021· 6 citedOpen Access
Heterogeneity in α-synuclein fibril activity correlates to disease phenotypes in Lewy body dementia
Acta Neuropathologica·2021· 39 citedOpen Access
Association of Genetic Variants With Primary Open-Angle Glaucoma Among Individuals With African Ancestry
JAMA·2019· 70 citedOpen Access
The human brainome: network analysis identifies HSPA2 as a novel Alzheimer’s disease target
Brain·2018· 46 citedOpen Access
Cover Image
Rapid Communications in Mass Spectrometry·2018Open Access
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Frequent Co-authors

Christine M. Hulette(21), Shih‐Hsiu J. Wang(18), Donald E. Schmechel(9), Mari H. Szymanski(8), Kathleen A. Welsh‐Bohmer(8), Todd J. Cohen(5), David C. Steffens(4), Dan G. Blazer(4), Jonathan L. Haines(4), Andrew B. West(4), Jay B. Lusk(4), Silas A. Buck(4), Pu‐Ting Xu(3), John R. Gilbert(3), Julie A. Schneider(3), Lawrence J. Shampine(3), Mark W. Massing(3), Xuejun Qin(3), Margaret A. Pericak‐Vance(3), James R. Burke(3)