George A. Garinis

University of Crete — Greece

Biochemistry, Genetics and Molecular Biology · Life Sciences

36h-index5.1kcitations87works7.22yr avg
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Research Topics

DNA Repair Mechanisms(35), Mitochondrial Function and Pathology(14), Genetics, Aging, and Longevity in Model Organisms(12), Epigenetics and DNA Methylation(7), RNA modifications and cancer(7)

Publications87 total

Molecular evolution of animal aging
The EMBO Journal·2026Open Access
Review of: "Neurodegeneration: A Convergence Hypothesis Linking Chronic Low‑Dose Diagnostic Radiation to Accelerated Decline"
2026Open Access
DNA damage in macrophages drives immune autoreactivity via nuclear antigen presentation
Nature Aging·2026· 1 citedOpen Access
Author Correction: ERCC1–XPF cooperates with CTCF and cohesin to facilitate the developmental silencing of imprinted genes
Nature Cell Biology·2025Open Access
Spotlight on innovation: key insights from the extracellular vesicle cluster meeting at the European Innovation Council
Cytotherapy·2025Open Access
From Genome to Geroscience: How DNA Damage Shapes Systemic Decline
BioEssays·2025· 2 citedOpen Access
Targeting DNA damage in ageing: towards supercharging DNA repair
Nature Reviews Drug Discovery·2025· 13 citedOpen Access
Loss of genome maintenance is linked to mTOR complex 1 signaling and accelerates podocyte damage
JCI Insight·2025· 5 citedOpen Access
The epitranscriptome: reshaping the DNA damage response
Trends in Cell Biology·2024· 3 cited
Looping forward: exploring R‐loop processing and therapeutic potential
FEBS Letters·2024· 6 citedOpen Access
Broken strands, broken minds: Exploring the nexus of DNA damage and neurodegeneration
DNA repair·2024· 7 cited
Transcription stress at telomeres leads to cytosolic DNA release and paracrine senescence
Nature Communications·2024· 16 citedOpen Access
Microglia-derived extracellular vesicles trigger age-related neurodegeneration upon DNA damage
Proceedings of the National Academy of Sciences·2024· 40 citedOpen Access
XPF interacts with TOP2B for R-loop processing and DNA looping on actively transcribed genes
Science Advances·2023· 9 citedOpen Access
Label-free human-disease characterization through circulating cell free DNA analysis using Raman Spectroscopy
Research Square (Research Square)·2023· 1 citedOpen Access
The DREAM complex functions as conserved master regulator of somatic DNA-repair capacities
Nature Structural & Molecular Biology·2023· 57 citedOpen Access
SpotitPy: a semi-automated tool for object-based co-localization of fluorescent labels in microscopy images
BMC Bioinformatics·2022· 3 citedOpen Access
DNA damage, inflammation and aging: Insights from mice
Frontiers in Aging·2022· 10 citedOpen Access
DNA damage in tissue-resident macrophages leads to age-related neurodegeneration
Research Square (Research Square)·2021Open Access
R-loops trigger the release of cytoplasmic ssDNAs leading to chronic inflammation upon DNA damage
Science Advances·2021· 62 citedOpen Access
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Frequent Co-authors

Jan H.J. Hoeijmakers(13), Gijsbertus T. J. van der Horst(11), Björn Schumacher(11), Georgia Chatzinikolaou(8), Laura J. Niedernhofer(7), Evi Goulielmaki(7), Kalliopi Stratigi(7), Harry van Steeg(6), Vassilis G. Gorgoulis(6), Andria R. Robinson(5), Ingrid van der Pluijm(5), Theodoros Kosteas(5), Ismene Karakasilioti(5), Renata M. C. Brandt(4), James R. Mitchell(4), Irene Kamileri(4), George P. Patrinos(4), Nick Spanakis(4), Jan Vijg(3), Theo G. M. F. Gorgels(3)