Lídia Mateo

Institute for Research in Biomedicine — Spain

Computer Science · Physical Sciences

12h-index967citations41works15.02yr avg
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Research Topics

Computational Drug Discovery Methods(15), Bioinformatics and Genomic Networks(9), Cancer Immunotherapy and Biomarkers(5), Chromosomal and Genetic Variations(5), Cancer Genomics and Diagnostics(4)

Publications41 total

TGF-β builds a dual immune barrier in colorectal cancer by impairing T cell recruitment and instructing immunosuppressive SPP1+ macrophages
Nature Genetics·2025· 2 cited
Post transcriptional control restrains the IL17–GCSF axis and limits neutrophil-driven breast cancer metastasis
2025Open Access
Systematic study of hybrid triplex topology and stability suggests a general triplex-mediated regulatory mechanism
Nucleic Acids Research·2025· 5 citedOpen Access
Systematic study of hybrid triplex topology and stability suggests a general triplex-mediated regulatory mechanism
2024Open Access
The efficacy of chemotherapy is limited by intratumoral senescent cells expressing PD-L2
Nature Cancer·2024· 83 citedOpen Access
Abstract C040: Investigating oncogene-inflammation cooperativity in pancreatic cancer
Cancer Research·2024
Iron accumulation drives fibrosis, senescence and the senescence-associated secretory phenotype
Nature Metabolism·2023· 160 citedOpen Access
Metastatic recurrence in colorectal cancer arises from residual EMP1+ cells
Nature·2022· 220 citedOpen Access
The efficacy of chemotherapy is limited by intratumoural senescent cells that persist through the upregulation of PD-L2
2022· 7 citedOpen Access
Mex3a marks drug-tolerant persister colorectal cancer cells that mediate relapse after chemotherapy
Nature Cancer·2022· 115 cited
A community challenge for a pancancer drug mechanism of action inference from perturbational profile data
Cell Reports Medicine·2022· 65 citedOpen Access
Identification and drug-induced reversion of molecular signatures of Alzheimer’s disease onset and progression in AppNL-G-F, AppNL-F, and 3xTg-AD mouse models
Genome Medicine·2021· 21 citedOpen Access
Identification and drug-induced reversion of molecular signatures of Alzheimer’s disease onset and progression in <i> App <sup>NL-G-F</sup> </i> , <i> App <sup>NL-F</sup> </i> and 3xTg-AD mouse models
2021Open Access
A Community Challenge for Pancancer Drug Mechanism of Action Inference from Perturbational Profile Data
SSRN Electronic Journal·2021· 3 citedOpen Access
Additional file 2 of Identification and drug-induced reversion of molecular signatures of Alzheimer’s disease onset and progression in AppNL-G-F, AppNL-F, and 3xTg-AD mouse models
Figshare·2021Open Access
A Community Challenge for Pancancer Drug Mechanism of Action Inference from Perturbational Profile Data
2020· 20 citedOpen Access
Personalized cancer therapy prioritization based on driver alteration co-occurrence patterns
Genome Medicine·2020· 22 citedOpen Access
Bioactivity Profile Similarities to Expand the Repertoire of COVID-19 Drugs
Journal of Chemical Information and Modeling·2020· 4 cited
Bioactivity Profile Similarities to Expand the Repertoire of COVID-19 Drugs
2020· 2 citedOpen Access
Bioactivity Profile Similarities to Expand the Repertoire of COVID-19 Drugs
2020· 1 citedOpen Access
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Frequent Co-authors

Patrick Aloy(19), Miquel Duran‐Frigola(17), Camille Stephan‐Otto Attolini(9), Oriol Guitart-Pla(9), Martino Bertoni(7), Pau Badia-i-Mompel(7), Eduardo Pauls(7), Víctor Alcalde(7), Gemma Turón(6), Joaquı́n Arribas(6), Núria Villegas(6), Isabelle Brun‐Heath(6), Carles Pons(5), Josefa González Pérez(5), Antonio Berenguer(4), Josefa González(4), Adrià Fernández‐Torras(4), Albert Gris‐Oliver(4), Marta Palafox(4), Maurizio Scaltriti(4)