Núria Villegas

Institute for Research in Biomedicine — Spain

Biochemistry, Genetics and Molecular Biology · Life Sciences

10h-index466citations25works2.52yr avg
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Research Topics

DNA and Nucleic Acid Chemistry(10), Advanced biosensing and bioanalysis techniques(7), RNA and protein synthesis mechanisms(6), Computational Drug Discovery Methods(5), Epigenetics and DNA Methylation(4)

Publications25 total

Systematic study of hybrid triplex topology and stability suggests a general triplex-mediated regulatory mechanism
Nucleic Acids Research·2025· 5 citedOpen Access
Systematic study of hybrid triplex topology and stability suggests a general triplex-mediated regulatory mechanism
2024Open Access
Controlled sulfur-based engineering confers mouldability to phosphorothioate antisense oligonucleotides
Nucleic Acids Research·2023· 18 citedOpen Access
Molecular basis or arginine and lysine DNA sequence-dependent thermo-stability modulation
Dipòsit Digital de la Universitat de Barcelona (Universitat de Barcelona)·2022· 10 citedOpen Access
The Impact of the HydroxyMethylCytosine epigenetic signature on DNA structure and function
PLoS Computational Biology·2021· 12 citedOpen Access
Bioactivity descriptors for uncharacterized chemical compounds
Nature Communications·2021· 95 citedOpen Access
Impact of DNA methylation on 3D genome structure
Nature Communications·2021· 146 citedOpen Access
A self-complementary DNA dodecamer duplex contaning 5-hydroxymethylcitosine
2021
The Impact of The Hydroxymethyl-Cytosine Epigenetic Signature on DNA Structure And Function
2020· 2 citedOpen Access
Bioactivity Profile Similarities to Expand the Repertoire of COVID-19 Drugs
Journal of Chemical Information and Modeling·2020· 4 cited
Impact of DNA methylation on 3D genome structure
Research Square (Research Square)·2020· 8 citedOpen Access
Bioactivity Profile Similarities to Expand the Repertoire of COVID-19 Drugs
2020· 2 citedOpen Access
Bioactivity Profile Similarities to Expand the Repertoire of COVID-19 Drugs
2020· 1 citedOpen Access
Bioactivity Profile Similarities to Expand the Repertoire of COVID-19 Drugs
2020Open Access
An artificial DNAzyme RNA ligase shows a reaction mechanism resembling that of cellular polymerases
Nature Catalysis·2019· 22 cited
The Origins and the Biological Consequences of the Pur/Pyr DNA·RNA Asymmetry
Chem·2019· 17 citedOpen Access
A multifunctional toolkit for target-directed cancer therapy
Chemical Communications·2018· 2 cited
Efficient siRNA–peptide conjugation for specific targeted delivery into tumor cells
Chemical Communications·2017· 20 cited
Rational design of novel N-alkyl-N capped biostable RNA nanostructures for efficient long-term inhibition of gene expression
Nucleic Acids Research·2016· 9 citedOpen Access
Can A Denaturant Stabilize DNA? Pyridine Reverses DNA Denaturation in Acidic pH
Angewandte Chemie International Edition·2015· 9 cited
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Frequent Co-authors

Isabelle Brun‐Heath(18), Modesto Orozco(14), Montserrat Terrazas(14), Guillem Portella(8), Patrick Aloy(7), Mireia Labrador(6), Pablo D. Dans(6), Lídia Mateo(6), Martino Bertoni(5), Miquel Duran‐Frigola(5), Pau Badia-i-Mompel(5), Eduardo Pauls(5), Oriol Guitart-Pla(5), Víctor Alcalde(5), Carlos González(5), Federica Battistini(5), Chiara Lara Castellazzi(5), Vito Genna(4), Gemma Turón(4), Carles Pons(4)