F.M. Cornelis

KU Leuven — Belgium

Medicine · Health Sciences

15h-index808citations54works3.72yr avg
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Research Topics

Osteoarthritis Treatment and Mechanisms(38), Inflammatory mediators and NSAID effects(11), Cancer-related molecular mechanisms research(9), Bone Metabolism and Diseases(9), Cancer-related gene regulation(7)

Publications54 total

Temporal profiling of lipid mediators in synovium and tibial plateau during joint inflammation in a collagenase-induced mouse model of osteoarthritis
Osteoarthritis and Cartilage·2025
PEROXISOMAL TRANSPORTER ABCD3 PROMOTES H3K79 METHYLATION AND MAINTAINS A HEALTHY CHONDROCYTE MOLECULAR IDENTITY
Osteoarthritis and Cartilage·2025
DIO2 REDUCES EXPRESSION OF PROTECTIVE HISTONE METHYLTRANSFERASE DOT1L IN ARTICULAR CARTILAGE AND OSTEOARTHRITIS
Osteoarthritis and Cartilage·2025
IGF1 RECEPTOR DOES NOT MEDIATE IGF1-INDUCED JOINT DAMAGE IN OSTEOARTHRITIS
Osteoarthritis and Cartilage·2025
Lipidomics unravels lipid changes in osteoarthritis articular cartilage
Annals of the Rheumatic Diseases·2025· 9 citedOpen Access
IGF1 drives Wnt-induced joint damage and is a potential therapeutic target for osteoarthritis
Nature Communications·2024· 17 citedOpen Access
POS1093 Extl3 INVOLVED IN THE REGULATION OF ENDOCHONDRAL OSSIFICATION IN AXIAL SpA
Annals of the Rheumatic Diseases·2024
The sacroiliac joint: An original and highly sensitive tool to highlight altered bone phenotype in murine models of skeletal disorders
Bone·2023
Osteomodulin downregulation is associated with osteoarthritis development
Bone Research·2023· 22 citedOpen Access
AB0030 OSTEOMODULIN DOWN-REGULATION IS ASSOCIATED WITH OSTEOARTHRITIS DEVELOPMENT
Annals of the Rheumatic Diseases·2023Open Access
Inhibition of KDM7A/B histone demethylases restores H3K79 methylation and protects against osteoarthritis
Annals of the Rheumatic Diseases·2023· 37 citedOpen Access
Osteomodulin down-regulation is associated with osteoarthritis development
Research Square (Research Square)·2023· 1 citedOpen Access
L’ostéomoduline joue un rôle majeur dans l’homéostasie de l’os et du cartilage
Revue du Rhumatisme·2022Open Access
Hypoxia and Wnt signaling inversely regulate expression of chondroprotective molecule ANP32A in articular cartilage
Osteoarthritis and Cartilage·2022· 10 citedOpen Access
POS0228 HYPOXIA AND INHIBITION OF WNT SIGNALING PROMOTE EXPRESSION OF THE PROTECTIVE MOLECULE ANP32A IN CARTILAGE
Annals of the Rheumatic Diseases·2022Open Access
Altered glucose and glutamine metabolism drives chondrocytes dysfunction in osteoarthritis
Bone Reports·2022Open Access
Inhibiting thyroid activation in aged human explants prevents mechanical induced detrimental signalling by mitigating metabolic processes
Lara D. Veeken·2022· 8 citedOpen Access
INHIBITION OF HISTONE DEMETHYLASES AS AN APPROACH TO RESTORE DEFICIENT DOT1L ACTIVITY IN OSTEOARTHRITIS
Osteoarthritis and Cartilage·2022
HYPOXIA AND LOW WNT SIGNALING PROMOTE ANP32A EXPRESSION IN CARTILAGE
Osteoarthritis and Cartilage·2022
THE HOMEOSTATIC HYPOXIC ENVIRONMENT IN ARTICULAR CARTILAGE SUSTAINS DOT1L ACTIVITY AND H3K79 METHYLATION TO PROTECT AGAINST OSTEOARTHRITIS
Osteoarthritis and Cartilage·2022
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Frequent Co-authors

Rik Lories(46), Silvia Monteagudo(29), Astrid De Roover(15), L. Storms(15), Ingrid Meulenbelt(12), Ana Escribano-Núñez(8), An Sermon(8), Tine Peeters(7), C. Cherifi(7), F. Cailotto(6), Rodrigo Coutinho de Almeida(5), Leire Casas-Fraile(5), J. Quintiens(5), Y.F. Ramos(4), Wouter den Hollander(4), Nico Lakenberg(4), X. Wang(4), Renée Van der Cruyssen(4), Tiago Pinto Coelho(4), Dirk Elewaut(4)