Axel A. Laminet

Medicine · Health Sciences

10h-index732citations13works0.02yr avg
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Research Topics

Monoclonal and Polyclonal Antibodies Research(5), Radiopharmaceutical Chemistry and Applications(5), Bacterial Genetics and Biotechnology(4), Antibiotic Resistance in Bacteria(4), HER2/EGFR in Cancer Research(3)

Publications13 total

Affinity, Specificity, and Kinetics of the Interaction of the SHC Phosphotyrosine Binding Domain with Asparagine-X-X-Phosphotyrosine Motifs of Growth Factor Receptors
Journal of Biological Chemistry·1996· 70 citedOpen Access
Targeting c-erbB-2 expressing tumors using single-chain Fv monomers and dimers.
PubMed·1995· 22 cited
Engineering disulfide-linked single-chain Fv dimers [(sFv')<sub>2</sub>] with improved solution and targeting properties: anti-digoxin 26–10 (sFv')<sub>2</sub> and anti-c-erbB-2 741F8 (sFv')<sub>2</sub> made by protein folding and bonded through C-terminal cysteinyl peptides
Protein Engineering Design and Selection·1995· 44 cited
Preclinical Studies and Optimization of Specific Tumor Delivery for 741F8 sFv, an Anti-c-erbB-2 Single-Chain Species
International Journal of Pharmacognosy·1995
Thermodynamic Partitioning Model for Hydrophobic Binding of Polypeptides by GroEL
Journal of Molecular Biology·1994· 66 cited
Mammalian Cell Expression of Single–Chain Fv (sFv) Antibody Proteins and Their C–terminal Fusions with Interleukin–2 and Other Effector Domains
Nature Biotechnology·1994· 61 cited
SINGLE-CHAIN Fv FUSIONS WITH C-TERMINAL CYSTEINE PEPTIDES IsFv′
Journal of Immunotherapy·1994· 1 cited
Tumor targeting in a murine tumor xenograft model with the (sFv′)2 divalent form of anti-c-erbB-2 single-chain Fv
Cell Biophysics·1994· 10 cited
Folding <i>in vitro</i> and transport <i>in vivo</i> of pre‐β‐lactamase are SecB independent
Molecular Microbiology·1991· 22 cited
Folding in vitro and transport in vivo of pre-beta-lactamase are SecB independent.
PubMed·1991· 22 cited
The Escherichia coli heat shock proteins GroEL and GroES modulate the folding of the beta-lactamase precursor.
The EMBO Journal·1990· 248 citedOpen Access
The precursor of beta-lactamase: purification, properties and folding kinetics.
The EMBO Journal·1989· 109 citedOpen Access
Three new restriction endonucleases<i>MaeI, MaeII</i>and<i>MaeIII</i>from<i>Methanococcus aeolicus</i>
Nucleic Acids Research·1984· 57 citedOpen Access

Frequent Co-authors

John E. McCartney(6), Andreas Plückthun(5), Robert M. Hudziak(5), James S. Huston(5), Hermann Oppermann(5), Michael A. Bookman(5), Mei-Sheng Tai(4), L. L. Houston(4), Gregory P. Adams(4), Walter F. Stafford(4), Gerald Apell(3), Sen Liu(3), I. Fand(3), Louis M. Weiner(2), Carol A. Kumamoto(2), M S Tai(2), Thomas Ziegelhoffer(1), Costa Georgopoulos(1), Leah Conroy(1), W. Michael Kavanaugh(1)