Mei-Sheng Tai

Medicine · Health Sciences

12h-index1.0kcitations21works0.02yr avg
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Research Topics

Monoclonal and Polyclonal Antibodies Research(12), Glycosylation and Glycoproteins Research(5), Protein purification and stability(5), Radiopharmaceutical Chemistry and Applications(5), HER2/EGFR in Cancer Research(4)

Publications21 total

Avidity-Mediated Enhancement of <i>In vivo</i> Tumor Targeting by Single-Chain Fv Dimers
Clinical Cancer Research·2006· 100 citedOpen Access
Optimization of in vivo tumor targeting in SCID mice with divalent forms of 741F8 anti-c-erbB-2 single-chain Fv: effects of dose escalation and repeated i.v. administration
Cancer Immunology Immunotherapy·1995· 12 citedOpen Access
Optimization of in vivo tumor targeting in SCID mice with divalent forms of 741F8 Anti-c-erbB-2 single-chain Fv: effects of dose escalation and repeated i.v. administration
Cancer Immunology Immunotherapy·1995
Single-Chain Fv Design and Production by Preparative Folding
1995· 16 cited
Engineering disulfide-linked single-chain Fv dimers [(sFv')<sub>2</sub>] with improved solution and targeting properties: anti-digoxin 26–10 (sFv')<sub>2</sub> and anti-c-erbB-2 741F8 (sFv')<sub>2</sub> made by protein folding and bonded through C-terminal cysteinyl peptides
Protein Engineering Design and Selection·1995· 44 cited
Preclinical Studies and Optimization of Specific Tumor Delivery for 741F8 sFv, an Anti-c-erbB-2 Single-Chain Species
International Journal of Pharmacognosy·1995
Mammalian Cell Expression of Single–Chain Fv (sFv) Antibody Proteins and Their C–terminal Fusions with Interleukin–2 and Other Effector Domains
Nature Biotechnology·1994· 61 cited
Tumor targeting in a murine tumor xenograft model with the (sFv′)2 divalent form of anti-c-erbB-2 single-chain Fv
Cell Biophysics·1994· 10 cited
Highly specific in vivo tumor targeting by monovalent and divalent forms of 741F8 anti-c-erbB-2 single-chain Fv.
PubMed·1993· 252 cited
Medical Applications of Single-Chain Antibodies
International Reviews of Immunology·1993· 172 cited
Antigen recognition and targeted delivery by the single-chain Fv
Cell Biophysics·1993· 29 cited
[3] Protein engineering of single-chain Fv analogs and fusion proteins
Methods in enzymology on CD-ROM/Methods in enzymology·1991· 211 cited
A micelle model for the sedimentation behavior of bovine β-casein
Biophysical Chemistry·1984· 31 cited
Pressure-jump kinetics of bovine β-casein micellization
Biophysical Chemistry·1984· 8 cited
Perturbation of ribosome subunit interaction by glutaraldehyde fixation
Biophysical Chemistry·1984· 1 cited
Models for the analytical ultracentrifuge behavior of helix pomatia α-hemocyanin
Biophysical Chemistry·1984· 7 cited
Models for the analytical ultracentrifuge behavior of helix pomatia α-hemocyanin
Biophysical Chemistry·1984· 4 cited
Relaxation kinetics of Helix pomatia α-hemocyanin
Archives of Biochemistry and Biophysics·1977· 10 cited
Mechanism of the hexamer-dodecamer reaction of lobster hemocyanin
Biophysical Chemistry·1975· 12 cited
Rate constants for the hexamer-dodecamer reaction of lobster hemocyanin
Biophysical Chemistry·1973· 17 cited
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Frequent Co-authors

John E. McCartney(12), James S. Huston(11), Hermann Oppermann(9), Gerson Kegeles(8), Gregory P. Adams(7), Walter F. Stafford(7), Michael A. Bookman(6), L. L. Houston(6), Louis M. Weiner(6), Axel A. Laminet(4), I. Fand(3), Donald Jin(3), Peter Keck(3), Robert M. Hudziak(3), Sen Liu(3), Ellen J. Wolf(3), Jamie Eisenberg(3), Frederick Warren(2), Gerald Apell(2), Michael C. Crossin(2)