Cedric J. Pearce

Mycosynthetix (United States) — United States

Medicine · Health Sciences

37h-index5.6kcitations187works1.52yr avg
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Research Topics

Microbial Natural Products and Biosynthesis(96), Fungal Biology and Applications(30), Marine Sponges and Natural Products(21), Carbohydrate Chemistry and Synthesis(14), Plant Pathogens and Fungal Diseases(13)

Publications187 total

Beyond Monomers: Discovery of Bioactive Naphthoquinone Heterodimers and Perenniporides from <i>Pyrenochaetopsis</i> Species
Journal of Natural Products·2025Open Access
Scaling up the production of fungal perylenequinones and investigating their biosynthesis through stable isotope labeling
Microbial Cell Factories·2025· 1 citedOpen Access
Role of physician-led neck ultrasound screening in lung cancer diagnostics
2025
Redox Homeostasis as a Key Regulator of Intramolecular Cyclization in Fungal Perylenequinones
ACS Chemical Biology·2025· 1 citedOpen Access
Studies on the epipolythiodioxopiperazine alkaloid verticillin D: Scaled production, streamlined purification, and absolute configuration
Phytochemistry·2025· 2 citedOpen Access
Verticillin A-Loaded Surgical Buttresses Prevent Local Pancreatic Cancer Recurrence in a Murine Model
Molecular Pharmaceutics·2025· 2 citedOpen Access
P158 Exploring differences across age groups in those diagnosed with lung cancer through the targeted lung health check
2024
Semisynthetic derivatives of the fungal metabolite eupenifeldin via targeting the tropolone hydroxy groups
Bioorganic & Medicinal Chemistry Letters·2024Open Access
Exploring the in vivo anti-cancer potential of Neosetophomone B in leukemic cells using a zebrafish xenograft model
Experimental Cell Research·2024· 4 cited
Verticillins: fungal epipolythiodioxopiperazine alkaloids with chemotherapeutic potential
Natural Product Reports·2024· 5 citedOpen Access
Semisynthesis, characterization, and biological evaluation of fluorinated analogues of the spirobisnaphthalene, diepoxin-η
Tetrahedron Letters·2023Open Access
Neosetophomone B induces apoptosis in multiple myeloma cells via targeting of AKT/SKP2 signaling pathway
Cell Biology International·2023· 9 citedOpen Access
In vitro evaluation of Neosetophomone B inducing apoptosis in cutaneous T cell lymphoma by targeting the FOXM1 signaling pathway
Journal of Dermatological Science·2023· 4 cited
Sheptide A: an antimalarial cyclic pentapeptide from a fungal strain in the Herpotrichiellaceae
The Journal of Antibiotics·2023· 3 citedOpen Access
Probing the Cytotoxic Signaling Induced by Eupenifeldin in Ovarian Cancer Models
Journal of Natural Products·2023· 4 citedOpen Access
<i>Trachymyrmex septentrionalis</i> ants promote fungus garden hygiene using <i>Trichoderma</i> -derived metabolite cues
Proceedings of the National Academy of Sciences·2023· 16 citedOpen Access
Exploration of Verticillins in High-Grade Serous Ovarian Cancer and Evaluation of Multiple Formulations in Preclinical In Vitro and In Vivo Models
Molecular Pharmaceutics·2023· 3 citedOpen Access
What was old is new again: Phenotypic screening of a unique fungal library yields pyridoxatin, a promising lead against extensively resistant Acinetobacter baumannii (AB5075)
Phytochemistry Letters·2023· 3 citedOpen Access
Supplementary Data from Verticillin A Causes Apoptosis and Reduces Tumor Burden in High-Grade Serous Ovarian Cancer by Inducing DNA Damage
2023Open Access
Supplementary Data from Verticillin A Causes Apoptosis and Reduces Tumor Burden in High-Grade Serous Ovarian Cancer by Inducing DNA Damage
2023Open Access
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Frequent Co-authors

Nicholas H. Oberlies(38), Huzefa A. Raja(12), Tamam El‐Elimat(12), Mansukh C. Wani(10), Mario Figueroa(9), Steven M. Swanson(9), Esperanza J. Carcache de Blanco(8), David J. Kroll(8), Kebin Liu(7), Tyler N. Graf(7), Audrey F. Adcock(7), Aaron H. Colby(7), Mark W. Grinstaff(7), Blaise A. Darveaux(6), Joanna E. Burdette(6), Sloan Ayers(6), Dafeng Yang(5), A. Douglas Kinghorn(4), Jimmy Orjala(4), Qi Shen(4)