Tyler N. Graf

University of North Carolina at Greensboro — United States

Medicine · Health Sciences

36h-index4.0kcitations127works1.62yr avg
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Research Topics

Silymarin and Mushroom Poisoning(43), Microbial Natural Products and Biosynthesis(23), Drug-Induced Hepatotoxicity and Protection(17), Fungal Biology and Applications(16), Berberine and alkaloids research(16)

Publications127 total

Natural pigments from the endophyte Aspergillus westerdijkiae and evaluation of their bioactivities
Microbial Cell Factories·2025Open Access
An antimicrobial daptide from human skin commensal Staphylococcus hominis protects against skin pathogens
Nature Communications·2025· 1 citedOpen Access
Studying the molecular mechanisms of tef (Eragrostis tef) antioxidant properties in human THP-1 monocytes
Journal of Functional Foods·2025· 1 citedOpen Access
Scaling up the production of fungal perylenequinones and investigating their biosynthesis through stable isotope labeling
Microbial Cell Factories·2025· 1 citedOpen Access
Natural Pigments from the Endophyte Aspergillus westerdijkiae and Evaluation of their Bioactivities
2025Open Access
Redox Homeostasis as a Key Regulator of Intramolecular Cyclization in Fungal Perylenequinones
ACS Chemical Biology·2025· 1 citedOpen Access
The importance of verifying biological activity predictions in metabolomics studies of natural products: A case study on antimicrobial properties of Cannabis sativa (hemp)
Phytochemistry Letters·2025Open Access
Corrigendum to ‘A gut response: Application of human enteroid monolayers to probe the mechanism of the goldenseal-mediated inhibition of metformin intestinal absorption’ [The Journal of Pharmacology and Experimental Therapeutics 392 (2025) 103597]
Journal of Pharmacology and Experimental Therapeutics·2025Open Access
An integrative genomic and chemical similarity approach linking fungal secondary metabolites and biosynthetic gene clusters
2025· 3 citedOpen Access
A gut response: Application of human enteroid monolayers to probe the mechanism of the goldenseal-mediated inhibition of metformin intestinal absorption
Journal of Pharmacology and Experimental Therapeutics·2025· 1 cited
Investigating catechin-mediated effects on drug solubility as a mechanism underlying a green tea-raloxifene pharmcokinetic interaction
Drug Metabolism and Pharmacokinetics·2024
Rifampin- and Silymarin-Mediated Pharmacokinetic Interactions of Exogenous and Endogenous Substrates in a Transgenic OATP1B Mouse Model
Molecular Pharmaceutics·2024· 5 citedOpen Access
Pharmacokinetic Effects of Different Models of Nonalcoholic Fatty Liver Disease in Transgenic Humanized OATP1B Mice
Drug Metabolism and Disposition·2024· 2 citedOpen Access
Green Tea Catechins Decrease Solubility of Raloxifene In Vitro and Its Systemic Exposure in Mice
Pharmaceutical Research·2024· 7 citedOpen Access
Semisynthesis, characterization, and biological evaluation of fluorinated analogues of the spirobisnaphthalene, diepoxin-η
Tetrahedron Letters·2023Open Access
Goldenseal-Mediated Inhibition of Intestinal Uptake Transporters Decreases Metformin Systemic Exposure in Mice
Drug Metabolism and Disposition·2023· 5 citedOpen Access
Evaluating the Antioxidant Properties of the Ancient-Crop Tef (Eragrostis tef) Grain Extracts in THP-1 Monocytes
Antioxidants·2023· 8 citedOpen Access
Goldenseal-mediated Inhibition of Enteric Uptake Transporters Decreases Metformin Systemic Exposure in Mice
Journal of Pharmacology and Experimental Therapeutics·2023· 1 citedOpen Access
What was old is new again: Phenotypic screening of a unique fungal library yields pyridoxatin, a promising lead against extensively resistant Acinetobacter baumannii (AB5075)
Phytochemistry Letters·2023· 3 citedOpen Access
Data from Milk Thistle and Prostate Cancer: Differential Effects of Pure Flavonolignans from <i>Silybum marianum</i> on Antiproliferative End Points in Human Prostate Carcinoma Cells
2023Open Access
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Frequent Co-authors

Nicholas H. Oberlies(39), Mansukh C. Wani(17), David J. Kroll(13), Nadja B. Cech(10), Mary F. Paine(8), Cedric J. Pearce(8), Stephen J. Polyak(7), Huzefa A. Raja(7), Arlene A. Sy‐Cordero(6), Steven M. Swanson(6), Monroe E. Wall(5), K.V. Rajagopalan(5), Daniel A. Todd(5), Joseph O. Falkinham(5), Tamam El‐Elimat(5), Audrey F. Adcock(5), Yuka Nakanishi(4), Rajesh Agarwal(4), Joshua J. Kellogg(4), Dongho Lee(4)