Mary F. Paine

Washington State University Spokane — United States

Pharmacology, Toxicology and Pharmaceutics · Life Sciences

48h-index9.2kcitations202works1.32yr avg
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Research Topics

Pharmacogenetics and Drug Metabolism(89), Drug Transport and Resistance Mechanisms(73), Drug-Induced Hepatotoxicity and Protection(33), Pharmacological Effects and Toxicity Studies(19), Cannabis and Cannabinoid Research(15)

Publications202 total

An exploratory evaluation of the interaction risk between herbal products and pharmaceutical medicines used concurrently for disease management in Blantyre, Malawi
Pharmaceutical Biology·2025· 3 citedOpen Access
Phytoconstituents as therapeutic agents in combating methotrexate-induced hepatotoxicity and nephrotoxicity
Expert Opinion on Drug Metabolism & Toxicology·2025
Limited Sampling Strategy of Rosuvastatin Single-Time-point Concentrations Accurately Estimate Exposure and Constitutive Transporter Activities in Healthy Adults
Therapeutic Drug Monitoring·2025
Corrigendum to ‘A gut response: Application of human enteroid monolayers to probe the mechanism of the goldenseal-mediated inhibition of metformin intestinal absorption’ [The Journal of Pharmacology and Experimental Therapeutics 392 (2025) 103597]
Journal of Pharmacology and Experimental Therapeutics·2025Open Access
Physiologically based pharmacokinetic modeling of cannabidiol (CBD), Δ-9- tetrahydrocannabinol (THC), and their active metabolites in healthy adults after administration of CBD and THC by multiple routes
Drug Metabolism and Pharmacokinetics·2025
Application of enteroid monolayers to evaluate potential pharmacokinetic oregano oil-drug interactions
Drug Metabolism and Pharmacokinetics·2025
The psychotropic botanicals Kratom and hemp induce select cytochrome P450 enzymes in human hepatocytes: Inhibition is not the only game in town
Drug Metabolism and Pharmacokinetics·2025
Botanical-drug interactions: Blazing the trail using translational tools
Drug Metabolism and Pharmacokinetics·2025
Identification and validation of selective endogenous substrates of organic anion transporter 1 (OAT1) versus OAT3 using metabolomics and in-vitro mechanistic studies
Drug Metabolism and Pharmacokinetics·2025
Evaluation of a cinnamomum verum product on the pharmacokinetics of the CYP2A6 model drugs nicotine and letrozole in healthy adults
Drug Metabolism and Pharmacokinetics·2025
From Discovery to Translation: Endogenous Substrates of OAT1 and OAT3 as Clinical Biomarkers for Renal Secretory Function
Clinical Pharmacology & Therapeutics·2025· 6 cited
Predicting in vivo cannabinoid-drug interactions mediated via inhibition of UDP-glucuronosyltransferases using in vitro studies and physiologically based pharmacokinetic modeling and simulations
Drug Metabolism and Disposition·2025· 2 cited
A gut response: Application of human enteroid monolayers to probe the mechanism of the goldenseal-mediated inhibition of metformin intestinal absorption
Journal of Pharmacology and Experimental Therapeutics·2025· 1 cited
Quantitative Contributions of Hepatic and Renal Organic Cation Transporters to the Clinical Pharmacokinetic Cimetidine–Metformin Interaction
Clinical Pharmacology & Therapeutics·2025· 4 cited
Identification of Potential Pre-Dose Endogenous Metabolic Features Associated with Metformin Plasma Exposure in Healthy Adults and Pediatric Patients (Abstract ID: 167055)
Journal of Pharmacology and Experimental Therapeutics·2025Open Access
Diclofenac Glucuronidation and Oxidation Are Inhibited by Curcumin Standard and Supplements (Abstract ID: 167709)
Journal of Pharmacology and Experimental Therapeutics·2025
From discovery to translation: Endogenous substrates of OAT1 and OAT3 as clinical biomarkers for renal secretory function
2025Open Access
The Pharmacokinetic Interaction Between Metformin and the Natural Product Goldenseal Is Metformin Dose‐Dependent: A Three‐Arm Crossover Study in Adults With Type 2 Diabetes
Clinical and Translational Science·2025· 1 citedOpen Access
Barriers to interprofessional mentorship in the health sciences
Mentoring & Tutoring Partnership in Learning·2025· 1 cited
Physiologically Based Pharmacokinetic Modeling of Cannabidiol, Delta‐9‐Tetrahydrocannabinol, and Their Metabolites in Healthy Adults After Administration by Multiple Routes
Clinical and Translational Science·2025· 7 citedOpen Access
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Frequent Co-authors

Kenneth E. Thummel(13), Paul B. Watkins(12), Nicholas H. Oberlies(8), Danny D. Shen(6), James D. Perkins(5), Richard R. Tidwell(5), Jashvant D. Unadkat(5), Kent L. Kunze(4), Christopher L. Marsh(4), Kenneth S. Lown(4), Anne B. Criss(4), Michael Zhuo Wang(4), Nadja B. Cech(4), Arlene S. Bridges(4), Allan E. Rettie(3), Darryl C. Zeldin(3), Jeannine M. Fisher(3), Steven Wrighton(3), Phyllissa Schmiedlin‐Ren(3), Stephen D. Hall(3)