Tim Manser

Thomas Jefferson University — United States

Immunology and Microbiology · Life Sciences

41h-index5.2kcitations153works0.02yr avg
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Research Topics

T-cell and B-cell Immunology(81), Monoclonal and Polyclonal Antibodies Research(62), Immune Cell Function and Interaction(53), Immunotherapy and Immune Responses(26), Immunodeficiency and Autoimmune Disorders(12)

Publications153 total

Faculty Opinions recommendation of Instructing durable humoral immunity for COVID-19 and other vaccinable diseases.
Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature·2022
Faculty Opinions recommendation of Promoter proximity defines mutation window for VH and VΚ genes rearranged to different J genes.
Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature·2022
Faculty Opinions recommendation of Cutting Edge: Nucleocapsid Vaccine Elicits Spike-Independent SARS-CoV-2 Protective Immunity.
Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature·2021
Faculty Opinions recommendation of SARS-CoV-2 mRNA vaccines induce persistent human germinal centre responses.
Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature·2021
Strongyloides stercoralis and HTLV-1 coinfection in CD34+ cord blood stem cell humanized mice: Alteration of cytokine responses and enhancement of larval growth
PLoS neglected tropical diseases·2021· 6 citedOpen Access
Faculty Opinions recommendation of Novel specialized cell state and spatial compartments within the germinal center.
Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature·2021
Faculty Opinions recommendation of Orthogonal SARS-CoV-2 Serological Assays Enable Surveillance of Low-Prevalence Communities and Reveal Durable Humoral Immunity.
Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature·2021
Faculty Opinions recommendation of Lack of evidence for a substantial rate of templated mutagenesis in B cell diversification.
Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature·2020
Faculty Opinions recommendation of Germline-Encoded Affinity for Cognate Antigen Enables Vaccine Amplification of a Human Broadly Neutralizing Response against Influenza Virus.
Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature·2019
Faculty Opinions recommendation of Clustered Mutations at the Murine and Human IgH Locus Exhibit Significant Linkage Consistent with Templated Mutagenesis.
Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature·2019
Faculty Opinions recommendation of BCR-dependent lineage plasticity in mature B cells.
Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature·2019
Faculty Opinions recommendation of Humanized mice reveal an essential role for human hepatocytes in the development of the liver immune system.
Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature·2018
Faculty Opinions recommendation of Enhanced Antibody Responses in a Novel NOG Transgenic Mouse with Restored Lymph Node Organogenesis.
Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature·2018
Faculty Opinions recommendation of Massively Parallel Sequencing of Peritoneal and Splenic B Cell Repertoires Highlights Unique Properties of B-1 Cell Antibodies.
Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature·2018
Humoral Immunity in Mice Transplanted with Hematopoietic Stem Cells Derived from Human Umbilical Cord Blood Recapitulates That of Human Infants
Stem Cells and Development·2017· 4 cited
Faculty Opinions recommendation of Independent roles of switching and hypermutation in the development and persistence of B lymphocyte memory.
Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature·2017
Faculty Opinions recommendation of Antibody-secreting plasma cells persist for decades in human intestine.
Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature·2017
Faculty Opinions recommendation of Cutting Edge: BAFF Overexpression Reduces Atherosclerosis via TACI-Dependent B Cell Activation.
Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature·2017
Faculty Opinions recommendation of Multi-tiered Reorganization of the Genome during B Cell Affinity Maturation Anchored by a Germinal Center-Specific Locus Control Region.
Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature·2016
Human B-1 and B-2 B Cells Develop from Lin−CD34+CD38lo Stem Cells
The Journal of Immunology·2016· 29 citedOpen Access
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Frequent Co-authors

Ziaur S. M. Rahman(6), Kalpit A. Vora(6), Lawrence J. Wysocki(5), Malcolm L. Gefter(5), Raja Vuyyuru(5), M L Gefter(3), Kathleen M. Tumas-Brundage(3), M L Gefter(3), Lynn Heltemes-Harris(3), Laurel B. Bernstein(2), Alan M. Weiner(2), Sambasiva P. Rao(2), Jeffrey V. Ravetch(2), R F Gesteland(2), Boris Alabyev(2), Shailaja Hande(2), Vicky M. Lentz(2), S Fish(2), A M Giusti(2), Jacqueline Sharon(2)