Laetitia Mazelin

Université Claude Bernard Lyon 1 — France

Biochemistry, Genetics and Molecular Biology · Life Sciences

17h-index2.0kcitations20works0.02yr avg
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Research Topics

Hedgehog Signaling Pathway Studies(6), Axon Guidance and Neuronal Signaling(6), Muscle Physiology and Disorders(5), Hippo pathway signaling and YAP/TAZ(4), Angiogenesis and VEGF in Cancer(2)

Publications20 total

Pharmacological inhibition of HDAC6 improves muscle phenotypes in dystrophin-deficient mice by downregulating TGF-β via Smad3 acetylation
Nature Communications·2022· 40 citedOpen Access
Hypothalamic–pituitary–adrenal axis activation and glucocorticoid‐responsive gene expression in skeletal muscle and liver of <i>Apc</i> mice
Journal of Cachexia Sarcopenia and Muscle·2022· 33 citedOpen Access
Lack of muscle mTOR kinase activity causes early onset myopathy and compromises whole‐body homeostasis
Journal of Cachexia Sarcopenia and Muscle·2018· 28 citedOpen Access
The Proto-oncogene c-Kit Inhibits Tumor Growth by Behaving as a Dependence Receptor
Molecular Cell·2018· 57 citedOpen Access
mTOR inactivation in myocardium from infant mice rapidly leads to dilated cardiomyopathy due to translation defects and p53/JNK-mediated apoptosis
Journal of Molecular and Cellular Cardiology·2016· 51 cited
Muscle-specific Drp1 overexpression impairs skeletal muscle growth via translational attenuation
Cell Death and Disease·2015· 134 citedOpen Access
DCC constrains tumour progression via its dependence receptor activity
Nature·2011· 100 cited
Myopathy caused by mammalian target of rapamycin complex 1 (mTORC1) inactivation is not reversed by restoring mitochondrial function
Proceedings of the National Academy of Sciences·2011· 43 cited
Table of Contents
Gastroenterology·2011Open Access
Variants in the Netrin-1 Receptor UNC5C Prevent Apoptosis and Increase Risk of Familial Colorectal Cancer
Gastroenterology·2011· 36 cited
Muscle inactivation of mTOR causes metabolic and dystrophin defects leading to severe myopathy
The Journal of Experimental Medicine·2009· 17 cited
Muscle inactivation of mTOR causes metabolic and dystrophin defects leading to severe myopathy
The Journal of Cell Biology·2009· 368 citedOpen Access
Inactivation of the UNC5C Netrin-1 Receptor Is Associated With Tumor Progression in Colorectal Malignancies
Gastroenterology·2007· 112 citedOpen Access
Netrin-1 controls colorectal tumorigenesis by regulating apoptosis
Nature·2004· 303 cited
Src Regulates Golgi Structure and KDEL Receptor-dependent Retrograde Transport to the Endoplasmic Reticulum
Journal of Biological Chemistry·2003· 108 citedOpen Access
Inhibition of Neuroepithelial Patched-Induced Apoptosis by Sonic Hedgehog
Science·2003· 315 cited
The dependence receptors DCC and UNC5H as a link between neuronal guidance and survival
Biology of the Cell·2003· 77 cited
The netrin-1 receptors UNC5H are putative tumor suppressors controlling cell death commitment
Proceedings of the National Academy of Sciences·2003· 187 citedOpen Access
Stress-induced disruption of colonic epithelial barrier: role of interferon-gamma and myosin light chain kinase in mice
HAL (Le Centre pour la Communication Scientifique Directe)·2003· 12 cited
Protective role of calcitonin gene-related peptide on acute and chronic gut inflammation in rats
Gastroenterology·1998Open Access

Frequent Co-authors

Patrick Mehlen(9), Laurent Schaeffer(8), Yann‐Gaël Gangloff(6), Jean‐Yves Scoazec(6), Agnès Bernet(5), Vincent Moncollin(4), Agnès Conjard‐Duplany(4), Valérie Risson(3), Dominique Baas(3), Damien Freyssenet(3), Klaas Romanino(3), Markus A. Rüegg(3), Marie‐May Coissieux(3), Marie Castets(3), Mila Roceri(2), Hervé Sanchez(2), Claudine Corneloup(2), Hélène Richard‐Bulteau(2), Alban Vignaud(2), Aurélia Defour(2)