Elizabeth A. Sweeny

Medical College of Wisconsin — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

18h-index1.9kcitations37works2.42yr avg
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Research Topics

Heat shock proteins research(9), Prion Diseases and Protein Misfolding(9), Protein Structure and Dynamics(7), Enzyme Structure and Function(7), Heme Oxygenase-1 and Carbon Monoxide(7)

Publications37 total

One academic health center’s response to a freedom of expression controversy
Academic Medicine·2025Open Access
Key roles of GAPDH, Hsp90, and NO in heme trafficking
Journal of Inorganic Biochemistry·2025Open Access
Heme allocation in eukaryotic cells relies on mitochondrial heme export through FLVCR1b to cytosolic GAPDH
Nature Communications·2025· 4 citedOpen Access
Heme allocation in eukaryotic cells relies on mitochondrial heme export through FLVCR1b to cytosolic GAPDH
2024· 6 citedOpen Access
Heme allocation in eukaryotic cells relies on mitochondrial heme export through FLVCR1b to cytosolic GAPDH
2024· 2 citedOpen Access
Functional interactions between NADPH oxidase 5 and actin
Frontiers in Cell and Developmental Biology·2023· 7 citedOpen Access
New roles for GAPDH, Hsp90, and NO in regulating heme allocation and hemeprotein function in mammals
Biological Chemistry·2022· 22 citedOpen Access
Identification of protein targets for NADPH oxidase 5 mediated oxidative modification
The FASEB Journal·2022
Nitric oxide and heme-NO stimulate superoxide production by NADPH oxidase 5
Free Radical Biology and Medicine·2021· 16 citedOpen Access
Dynamic Regulation of NADPH Oxidase 5 by Heme, Nitric oxide, and Hsp90
Free Radical Biology and Medicine·2020
Dynamic regulation of NADPH oxidase 5 by intracellular heme levels and cellular chaperones
Redox Biology·2020· 18 citedOpen Access
GAPDH delivers heme to soluble guanylyl cyclase
Journal of Biological Chemistry·2020· 66 citedOpen Access
Structural and mechanistic insights into Hsp104 function revealed by synchrotron X-ray footprinting
Journal of Biological Chemistry·2019· 21 citedOpen Access
Mining Disaggregase Sequence Space to Safely Counter TDP-43, FUS, and α-Synuclein Proteotoxicity
Cell Reports·2019· 44 citedOpen Access
Hsp104 and Potentiated Variants Can Operate as Distinct Nonprocessive Translocases
Biophysical Journal·2019· 30 citedOpen Access
Glyceraldehyde-3-phosphate dehydrogenase is a chaperone that allocates labile heme in cells
Journal of Biological Chemistry·2018· 128 citedOpen Access
Nuclear-Import Receptors Reverse Aberrant Phase Transitions of RNA-Binding Proteins with Prion-like Domains
Cell·2018· 467 citedOpen Access
Kinetic Mechanism of ATP-Dependent Disaggregating Motor Saccharomyces cerevisiae Hsp104
Biophysical Journal·2018Open Access
Hsp90 chaperones hemoglobin maturation in erythroid and nonerythroid cells
Proceedings of the National Academy of Sciences·2018· 57 citedOpen Access
Ratchet-like polypeptide translocation mechanism of the AAA+ disaggregase Hsp104
Science·2017· 271 citedOpen Access
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Frequent Co-authors

James Shorter(19), Dennis J. Stuehr(12), Meredith E. Jackrel(11), Morgan E. DeSantis(7), Korrie L. Mack(7), Yue Dai(6), Pranjal Biswas(5), Adam L. Yokom(4), Daniel R. Southworth(4), Matthew Sochor(4), Simon Schlanger(4), Arnab Ghosh(4), Dhanya T. Jayaram(4), Stephanie N. Gates(3), Alexandrea N. Rizo(3), Nathan M. Kendsersky(3), C.E. Buell(3), Edward Chuang(3), Mariana P. Torrente(3), Eunice H. Leung(3)