Wuhong Pei

National Human Genome Research Institute — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

21h-index3.3kcitations45works1.02yr avg
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Research Topics

Developmental Biology and Gene Regulation(6), Congenital heart defects research(6), CRISPR and Genetic Engineering(5), RNA modifications and cancer(5), Mitochondrial Function and Pathology(4)

Publications45 total

Tnfrsf10 Signaling is Required to Maintain the Stem Cell Niche in the Zebrafish Lateral Line
2025· 1 citedOpen Access
Zrsr2 Is Essential for the Embryonic Development and Splicing of Minor Introns in RNA and Protein Processing Genes in Zebrafish
International Journal of Molecular Sciences·2022· 6 citedOpen Access
Suppressing STAT3 activity protects the endothelial barrier from VEGF-mediated vascular permeability
Disease Models & Mechanisms·2021· 70 citedOpen Access
Early-Onset Stroke and Vasculopathy Associated with Mutations in ADA2
UNC Libraries·2020· 46 citedOpen Access
Zrsr2 Deficient Zebrafish Display Hematopoietic Defects and U12-Type Intron Retention in mRNA Processing Genes
Blood·2020· 1 cited
Suppressing STAT3 activity protects the endothelial barrier from VEGF-mediated vascular permeability
2020· 12 citedOpen Access
Somatic Mutations in <i>UBA1</i> and Severe Adult-Onset Autoinflammatory Disease
New England Journal of Medicine·2020· 1.1k citedOpen Access
Somatic Mutations in a Single Residue of UBA1 Cause VEXAS, a Severe Adult-Onset Rheumatic Disease Presenting as Relapsing Polychondritis, Polyarteritis Nodosa, or Giant Cell Arteritis
White Rose Research Online (University of Leeds, The University of Sheffield, University of York)·2020
A Novel CRISPR-based Series of Retinitis Pigmentosa Models in Zebrafish
Investigative Ophthalmology & Visual Science·2020Open Access
A subset of SMN complex members have a specific role in tissue regeneration via ERBB pathway-mediated proliferation
npj Regenerative Medicine·2020· 18 citedOpen Access
Novel Zebrafish Autosomal Recessive Retinitis Pigmentosa Disease Models Created by CRISPR/Cas9 Gene Editing
Investigative Ophthalmology & Visual Science·2019· 1 citedOpen Access
A subset of SMN complex members have a specific role in tissue regeneration via ERBB pathway-mediated proliferation
2019· 1 cited
Microinjection in Zebrafish for Genome Editing and Functional Studies
Methods in molecular biology·2018· 8 cited
Multiplexed CRISPR/Cas9 Targeting of Genes Implicated in Retinal Regeneration and Degeneration
Frontiers in Cell and Developmental Biology·2018· 27 citedOpen Access
Modeling Niemann-Pick disease type C1 in zebrafish: a robust platform for <i>in vivo</i> screening of candidate therapeutic compounds
Disease Models & Mechanisms·2018· 44 citedOpen Access
Guided genetic screen to identify genes essential in the regeneration of hair cells and other tissues
npj Regenerative Medicine·2018· 40 citedOpen Access
Aberrant tRNA processing causes an autoinflammatory syndrome responsive to TNF inhibitors
Annals of the Rheumatic Diseases·2018· 55 citedOpen Access
Novel degenerative and developmental defects in a zebrafish model of mucolipidosis type IV
Human Molecular Genetics·2017· 21 citedOpen Access
A high-throughput functional genomics workflow based on CRISPR/Cas9-mediated targeted mutagenesis in zebrafish
Nature Protocols·2016· 248 citedOpen Access
Extracellular HSP60 triggers tissue regeneration and wound healing by regulating inflammation and cell proliferation
npj Regenerative Medicine·2016· 78 citedOpen Access
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Frequent Co-authors

Shawn M. Burgess(23), Lisha Xu(11), Raman Sood(9), Benjamin Feldman(9), Blake Carrington(6), Amanda K. Ombrello(5), Kevin Bishop(5), Gaurav K. Varshney(5), Wanxia Li Tsai(4), James C. Mullikin(4), Massimo Gadina(4), Ivona Aksentijevich(4), Sunny C. Huang(4), Kade Pettie(4), Bing Shen(4), Patrycja Hoffmann(3), Karyl S. Barron(3), Chyi‐Chia Richard Lee(3), Jae Jin Chae(3), William A. Gahl(3)