Michael W. McBurney

University of Ottawa — Canada

Medicine · Health Sciences

67h-index23.1kcitations181works0.02yr avg
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Research Topics

Sirtuins and Resveratrol in Medicine(65), Adipose Tissue and Metabolism(30), Autophagy in Disease and Therapy(22), Pluripotent Stem Cells Research(17), Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities(14)

Publications180 total

Supplementary Material for: Resveratrol Inhibits Neointimal Growth after Arterial Injury in High-Fat-Fed Rodents: The Roles of SIRT1 and AMPK
Figshare·2020Open Access
Resveratrol Inhibits Neointimal Growth after Arterial Injury in High-Fat-Fed Rodents: The Roles of SIRT1 and AMPK
Journal of Vascular Research·2020· 6 citedOpen Access
Unconventional Secretion of Adipocyte Fatty Acid Binding Protein 4 Is Mediated By Autophagic Proteins in a Sirtuin-1–Dependent Manner
Diabetes·2019· 45 citedOpen Access
Ablation of Sirtuin 1 Deacetylase Activity Induces Pulmonary Emphysema by Inducing Cellular Senescence and Disrupting Circadian Clock in Mice (P01-022-19)
Current Developments in Nutrition·2019· 1 citedOpen Access
IL-15 improves skeletal muscle oxidative metabolism and glucose uptake in association with increased respiratory chain supercomplex formation and AMPK pathway activation
Biochimica et Biophysica Acta (BBA) - General Subjects·2018· 48 citedOpen Access
Contribution of NK cells to immunotherapy mediated by PD-1/PD-L1 blockade
Journal of Clinical Investigation·2018· 796 citedOpen Access
Modulating SIRT1 activity variously affects thymic lymphoma development in mice
Experimental Cell Research·2018· 2 cited
Food anticipatory activity on a calorie-restricted diet is independent of Sirt1
PLoS ONE·2018· 6 citedOpen Access
Methionine metabolism is essential for <scp>SIRT</scp> 1‐regulated mouse embryonic stem cell maintenance and embryonic development
The EMBO Journal·2017· 87 citedOpen Access
Ablation of systemic SIRT1 activity promotes nonalcoholic fatty liver disease by affecting liver-mesenteric adipose tissue fatty acid mobilization
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease·2017· 43 cited
Ablation of systemic SIRT1 activity promotes nonalcoholic fatty liver disease by affecting liver‐mesenteric adipose tissue fatty acid mobilization
The FASEB Journal·2017· 2 cited
Reversible modulation of SIRT1 activity in a mouse strain
PLoS ONE·2017· 8 citedOpen Access
Abstract 19440: Dichloroacetate Fails to Improve Exaggerated Chronic-Hypoxia Induced Pulmonary Hypertension in Sirtuin 1 Mutant Mice
Circulation·2016
A CREB-Sirt1-Hes1 Circuitry Mediates Neural Stem Cell Response to Glucose Availability
Cell Reports·2016· 69 citedOpen Access
Correction: Sirt1 Regulates Insulin Secretion by Repressing UCP2 in Pancreatic β Cells
PLoS Biology·2015· 20 citedOpen Access
Production of Immunoabsorbent Nanoparticles by Displaying Single‐Domain Protein A on Potato Virus X
Macromolecular Bioscience·2015· 35 cited
Sirt1-deficiency causes defective protein quality control
Scientific Reports·2015· 34 citedOpen Access
The deacetylase Sirt1 is an essential regulator of Aire-mediated induction of central immunological tolerance
Nature Immunology·2015· 84 cited
Sirtuin 1 Is a Negative Regulator of Parathyroid Hormone Stimulation of Matrix Metalloproteinase 13 Expression in Osteoblastic Cells
Journal of Biological Chemistry·2015· 31 citedOpen Access
Sirt1-Deficient Mice Have Hypogonadotropic Hypogonadism due to Defective GnRH Neuronal Migration
Molecular Endocrinology·2014· 32 citedOpen Access
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Frequent Co-authors

Karen Jardine(7), Leonard Guarente(5), Madeleine E. Lemieux(4), Wei Gu(4), Gino Boily(4), Hongwei Yao(4), Irfan Rahman(4), William A. Staines(3), Elizabeth Jones-Villeneuve(3), Mary K. Edwards(3), Valter D. Longo(3), Chaker N. Adra(3), Poppo H. Boer(3), Isaac K. Sundar(3), Frédéric Picard(2), Constance G. Craig(2), Maria Carla Motta(2), John C. Bell(2), Wei Xu(2), David Sinclair(2)