Apeng Wang

Chinese Academy of Medical Sciences & Peking Union Medical College — China

Biochemistry, Genetics and Molecular Biology · Life Sciences

16h-index648citations47works1.62yr avg
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Research Topics

Cancer therapeutics and mechanisms(17), Phenothiazines and Benzothiazines Synthesis and Activities(14), Tuberculosis Research and Epidemiology(10), Quinazolinone synthesis and applications(7), Hepatitis B Virus Studies(6)

Publications47 total

Discovery, Design, and Synthesis of Novel 2-Benzyl-2,7-diazaspiro[3.5]nonane Benzothiazinones with Broad-Spectrum Antimycobacterial Activity
Journal of Medicinal Chemistry·2025
Improved Antitumor Efficiency of N4-Tetradecyloxycarbonyl Gemcitabine-Loaded Liposomes for Pancreatic Cancer Chemotherapy
International Journal of Nanomedicine·2024· 1 citedOpen Access
A Dual-Function LipoAraN-E5 Coloaded with <i>N</i><sup>4</sup>-Myristyloxycarbonyl-1-β-<scp>d</scp>-arabinofuranosylcytosine (AraN) and a CXCR4 Antagonistic Peptide (E5) for Blocking the Dissemination of Acute Myeloid Leukemia
ACS Nano·2024· 2 cited
ApoE Mimetic Peptide COG1410 Kills Mycobacterium smegmatis via Directly Interfering ClpC’s ATPase Activity
Antibiotics·2024· 2 citedOpen Access
Identification of dihydroquinolizinone derivatives with nitrogen heterocycle moieties as new anti-HBV agents
European Journal of Medicinal Chemistry·2024· 3 cited
Lipid-like gemcitabine diester-loaded liposomes for improved chemotherapy of pancreatic cancer
Journal of Controlled Release·2023· 12 cited
Investigation of novel 5ʹ-amino adenosine derivatives with potential anti-Zika virus activity
European Journal of Medicinal Chemistry·2023· 6 cited
Design, synthesis and antitubercular activity of novel N-(amino)piperazinyl benzothiazinones with improved safety
European Journal of Medicinal Chemistry·2023· 8 cited
Identification of 3-nitrophenol ester derivatives as novel quorum-sensing inhibitors of Pseudomonas aeruginosa
Journal of Molecular Structure·2022· 6 cited
Novel 5-Fluorouracil Carbonate-Loaded Liposome: Preparation, <i>In Vitro</i>, and <i>In Vivo</i> Evaluation as an Antitumor Agent
Molecular Pharmaceutics·2022· 6 cited
Identification of dihydroquinolizinone derivatives with cyclic ether moieties as new anti-HBV agents
European Journal of Medicinal Chemistry·2022· 10 cited
Identification of Dihydroquinolizinone Derivatives with Cyclic Ether Moieties as New Anti-HBV Agents
SSRN Electronic Journal·2022Open Access
Design, synthesis and biological evaluation of nitrofuran-1,3,4-oxadiazole hybrids as new antitubercular agents
Bioorganic & Medicinal Chemistry·2021· 12 citedOpen Access
Identification of (6S)-cyclopropyl-6,7-dihydropyrazolo[1,5-a]pyrazine-5(4H)-carboxamines as new HBV capsid assembly modulators
European Journal of Medicinal Chemistry·2021· 9 citedOpen Access
Optimization and SAR research at the piperazine and phenyl rings of JNJ4796 as new anti-influenza A virus agents, part 1
European Journal of Medicinal Chemistry·2021· 13 cited
Design, synthesis and biological activity of N-(amino)piperazine-containing benzothiazinones against Mycobacterium tuberculosis
European Journal of Medicinal Chemistry·2021· 22 cited
Design, synthesis and antimycobacterial activity of new benzothiazinones inspired by rifampicin/rifapentine
Bioorganic Chemistry·2020· 11 cited
Identification of benzothiazinones containing 2-benzyl-2,7-diazaspiro[3.5]nonane moieties as new antitubercular agents
European Journal of Medicinal Chemistry·2020· 17 cited
Amino acid prodrugs of NVR3-778: Design, synthesis and anti-HBV activity
Bioorganic & Medicinal Chemistry Letters·2020· 11 cited
Identification of benzothiazinones containing an oxime functional moiety as new anti-tuberculosis agents
European Journal of Medicinal Chemistry·2019· 28 citedOpen Access
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Frequent Co-authors

Mingliang Liu(37), Kai Lv(33), Yu Lu(21), Zeyu Tao(16), Huiyuan Guo(11), Chao Ma(10), Shuo Wu(9), Hongjian Wang(8), Shijie Xu(8), Xican Ma(7), Aoyu Wang(7), Menghao Huang(7), Yunhe Geng(7), Guimin Xia(7), Xiaoyu Qin(7), Yuhuan Li(7), Zhehui Zhao(7), Pingsheng Lei(7), Bin Wang(5), Bin Wang(5)