Xican Ma

Chinese Academy of Medical Sciences & Peking Union Medical College — China

Biochemistry, Genetics and Molecular Biology · Life Sciences

8h-index243citations19works2.52yr avg
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Research Topics

Cancer therapeutics and mechanisms(7), Tuberculosis Research and Epidemiology(4), Quinazolinone synthesis and applications(4), Antibiotic Resistance in Bacteria(3), Hepatitis B Virus Studies(3)

Publications19 total

Evolution of 8-esterified cycloberberines as a novel class of antibacterial agents against MDR gram-positive strains by targeting DNA polymerase IIIC
Bioorganic Chemistry·2025· 2 cited
Pyrylium derivatives as outer membrane permeabilizers against MDR gram-negative bacteria via multi-target mode of action
European Journal of Medicinal Chemistry·2025· 4 cited
Lycorine esters exert anti-HCoV-OC43 effect through reversibly acylating cysteine residue in the nsp 12 NiRAN domain
Bioorganic Chemistry·2024· 1 cited
Identification of dihydroquinolizinone derivatives with nitrogen heterocycle moieties as new anti-HBV agents
European Journal of Medicinal Chemistry·2024· 3 cited
Author correction to ‘Discovery and identification of EIF2AK2 as a direct key target of berberine for anti-inflammatory effects’ [Acta Pharmaceutica Sinica B 13 (2023) 2138–2151]
Acta Pharmaceutica Sinica B·2023· 1 citedOpen Access
Design, synthesis and triglyceride-lowering activity of tricyclic matrine derivatives for the intervention of non-alcoholic fatty liver disease
Bioorganic Chemistry·2023· 5 cited
Synthesis of peptidomimetics as antibiotic adjuvants for combination with aztreonam to combat MDR Pseudomonas aeruginosa
European Journal of Medicinal Chemistry·2023· 4 citedOpen Access
Evolution and development of potent monobactam sulfonate candidate IMBZ18g as a dual inhibitor against MDR Gram-negative bacteria producing ESBLs
Acta Pharmaceutica Sinica B·2023· 7 citedOpen Access
Discovery and identification of EIF2AK2 as a direct key target of berberine for anti-inflammatory effects
Acta Pharmaceutica Sinica B·2022· 77 citedOpen Access
Discovery and development of palmatine analogues as anti-NASH agents by activating farnesoid X receptor (FXR)
European Journal of Medicinal Chemistry·2022· 16 citedOpen Access
Identification of dihydroquinolizinone derivatives with cyclic ether moieties as new anti-HBV agents
European Journal of Medicinal Chemistry·2022· 10 cited
Discovery of new riminophenazine analogues as antimycobacterial agents against drug-resistant Mycobacterium tuberculosis
Bioorganic Chemistry·2022· 2 cited
Identification of Dihydroquinolizinone Derivatives with Cyclic Ether Moieties as New Anti-HBV Agents
SSRN Electronic Journal·2022Open Access
Protective effect and action mechanism of modified Ershiwuwei Songshi pills on chronic liver injury induced by CCL4.
Medicinal plant·2020
Identification of benzothiazones containing a hexahydropyrrolo[3,4-<i>c</i>]pyrrol moiety as antitubercular agents against MDR-MTB
RSC Advances·2020· 11 citedOpen Access
Identification of benzothiazinones containing an oxime functional moiety as new anti-tuberculosis agents
European Journal of Medicinal Chemistry·2019· 28 citedOpen Access
N-(2-Phenoxy)ethyl imidazo[1,2-a]pyridine-3-carboxamides containing various amine moieties: Design, synthesis and antitubercular activity
Chinese Chemical Letters·2019· 14 cited
hERG optimizations of IMB1603, discovery of alternative benzothiazinones as new antitubercular agents
European Journal of Medicinal Chemistry·2019· 16 cited
Design, synthesis and biological activity of N-(2-phenoxy)ethyl imidazo[1,2-a]pyridine-3-carboxamides as new antitubercular agents
European Journal of Medicinal Chemistry·2019· 42 cited

Frequent Co-authors

Danqing Song(10), Kai Lv(8), Apeng Wang(7), Mingliang Liu(7), Tianyun Fan(5), Yanxiang Wang(5), Bing Han(5), Zeyu Tao(4), Chao Ma(4), Aoyu Wang(4), Yu Lu(4), Yuheng Mei(4), Yinghong Li(4), Hongbin Deng(3), Liping Zhao(3), Yonghua Liu(3), Jingyang Zhu(3), Yonghua Liu(3), Shuo Wu(3), Yuhuan Li(3)