Harald Schwalbe

Goethe University Frankfurt — Germany

Biochemistry, Genetics and Molecular Biology · Life Sciences

73h-index22.5kcitations793works3.72yr avg
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Research Topics

RNA and protein synthesis mechanisms(233), DNA and Nucleic Acid Chemistry(133), Protein Structure and Dynamics(128), Enzyme Structure and Function(100), RNA modifications and cancer(97)

Publications792 total

Rapid identification of EphA2 ligand-binding domain binders through an optimized NMR fragment-screening workflow
2026Open Access
Cupriavidus necator, an alternative source for isotopic enrichment of proteins expressed in insect cells for NMR investigations
Journal of Biomolecular NMR·2026Open Access
Integrative In Silico and In Vitro Screening of Low Molecular Weight Compounds Targeting SARS‐CoV‐2 RNA Elements
ChemBioChem·2025Open Access
LSD1 inhibition enhances venetoclax efficacy in Acute Myeloid Leukemia via metabolic rewiring
Blood·2025
Structure‐Based Rational Design of a Selective Hydrolase Inhibitor of the Severe Acute Respiratory Syndrome Coronavirus‐2 Nsp3 Macrodomain
ChemBioChem·2025Open Access
The Zuo1 C-terminal domain stabilizes DNA guanosine quadruplex (G4) structures located on Chromosome IX in <i>Saccharomyces cerevisiae</i>
Nucleic Acids Research·2025Open Access
Structural Role of Conformational Heterogeneity and Juxtamembrane Regions in the Ephrin A1 Interactions With the EphA2 Receptor Ligand-binding Domain
Journal of Molecular Biology·2025· 1 citedOpen Access
Integrated NMR and MD structure and dynamics of the stem–loop-II motif (s2m) from the Omicron variant of SARS-CoV-2
RNA·2025Open Access
Targeting the SARS-CoV-2 RNA Translation Initiation Element SL1 by Molecules of Low Molecular Weight
Journal of the American Chemical Society·2025Open Access
1H, 13C and 15N chemical shift assignment for stem-loop 5a from the 5‘UTR of HCoV-229E
Biomolecular NMR Assignments·2025Open Access
G-quadruplex-targeting indoloquinoxaline derivative modulates host immunity against <i>Leishmania donovani</i>
NAR Molecular Medicine·2025· 1 citedOpen Access
<scp>NMR</scp> screening of low molecular weight inhibitors targeting the papain‐like protease (<scp>PLPro</scp>) of <scp>SARS</scp>‐<scp>CoV</scp>‐2
FEBS Open Bio·2025· 1 citedOpen Access
Structural heterogeneity and dynamics in the apical stem loop of s2m from SARS-CoV-2 Delta by an integrative NMR spectroscopy and MD simulation approach
Nucleic Acids Research·2025· 4 citedOpen Access
Cover Feature: Nanosecond Hyperquenching for Electron Cryo‐Microscopy Without Air‐Water Interface Artifacts
Chemistry - A European Journal·2025Open Access
Structural Insights into Spare-Tire DNA G-Quadruplex from the Human <i>VEGF</i> Promoter
ACS Chemical Biology·2025· 2 citedOpen Access
Exploring the Modulation of the Complex Folding Landscape of Human Telomeric DNA by a Low Molecular Weight Ligand
Chemistry - A European Journal·2025· 1 citedOpen Access
Protocol for the purification, analysis, and handling of acyl carrier proteins from type I fatty acid and polyketide synthases
STAR Protocols·2025· 3 citedOpen Access
NMR characterisation of the antibiotic resistance-mediating 32mer RNA from the 23S ribosomal RNA
Biomolecular NMR Assignments·2025· 3 citedOpen Access
Nanosecond Hyperquenching for Electron Cryo‐Microscopy Without Air‐Water Interface Artifacts
Chemistry - A European Journal·2025· 1 citedOpen Access
G-quadruplexes and their unexpected ability to fold proteins
Proceedings of the National Academy of Sciences·2025· 1 citedOpen Access
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Frequent Co-authors

Boris Fürtig(11), Jens Wöhnert(9), Krishna Saxena(8), Christian Richter(7), Lorna J. Smith(6), Christopher M. Dobson(5), Hendrik R. A. Jonker(5), Frank Löhr(5), Janina Buck(5), J. Noeske(5), Matthias Buck(4), Shaun B. Grimshaw(3), Hamid R. Nasiri(3), Klaus M. Fiebig(3), Barbara Imperiali(3), Sridhar Sreeramulu(3), Florian Buhr(2), Ivano Bertini(2), Claudio Luchinat(2), Gregg Siegal(2)