John-Mark Fitzpatrick

Trinity College — Canada

Medicine · Health Sciences

6h-index229citations9works5.02yr avg
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Research Topics

Cannabis and Cannabinoid Research(5), Multiple Sclerosis Research Studies(2), Immune Response and Inflammation(2), Neuroinflammation and Neurodegeneration Mechanisms(2), MicroRNA in disease regulation(1)

Publications9 total

Cannflavin A inhibits TLR4-induced chemokine and cytokine expression in human macrophages
Natural Product Research·2024· 5 citedOpen Access
Botanically-Derived Δ9-Tetrahydrocannabinol and Cannabidiol, and Their 1:1 Combination, Modulate Toll-like Receptor 3 and 4 Signalling in Immune Cells from People with Multiple Sclerosis
Molecules·2022· 11 citedOpen Access
Phytocannabinoid‐dependent mTORC1 regulation is dependent upon inositol polyphosphate multikinase activity
British Journal of Pharmacology·2020· 22 citedOpen Access
MyD88-dependent and -independent signalling via TLR3 and TLR4 are differentially modulated by Δ9-tetrahydrocannabinol and cannabidiol in human macrophages
Journal of Neuroimmunology·2020· 62 cited
Assessing Toll-like receptor 3/4 signalling as a phytocannabinoid target in immune cells
Arrow@dit (Dublin Institute of Technology)·2020Open Access
Toll-like receptor signalling as a cannabinoid target in Multiple Sclerosis
Neuropharmacology·2016· 42 cited
Modulation of TLR3/TLR4 inflammatory signaling by the GABAB receptor agonist baclofen in glia and immune cells: relevance to therapeutic effects in multiple sclerosis
Frontiers in Cellular Neuroscience·2015· 56 citedOpen Access
MicroRNA: Key regulators of oligodendrocyte development and pathobiology
The International Journal of Biochemistry & Cell Biology·2015· 31 cited
An investigation into baclofen as a modulator of central TLR3/TLR4 signalling
2015

Frequent Co-authors

Eric J. Downer(7), William Hind(3), Tadhg Crowley(2), John F. Cryan(2), Orna O’Toole(2), Olivia F. O’Leary(2), Lisa Costelloe(2), Eleanor Minogue(1), Lucy Curham(1), Harry Tyrrell(1), Philip Gavigan(1), Teun Kuijper(1), Rebecca Cogwell Anderson(1), Kieran W. McDermott(1), Joseph Damstra‐Oddy(1), Eleanor C. Warren(1), Christopher J. Perry(1), Yann Desfougères(1), Judith Schaf(1), Adolfo Saiardi(1)