Jeffrey M. Trent

Translational Genomics Research Institute — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

113h-index55.1kcitations805works3.92yr avg
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Research Topics

Cancer Genomics and Diagnostics(159), Molecular Biology Techniques and Applications(72), Chromatin Remodeling and Cancer(67), Cancer Mechanisms and Therapy(63), Gene expression and cancer classification(59)

Publications801 total

ALTseqTM, a rapid (< 48 hours) whole genome sequencing clinical test for Acute Myeloid Leukemia (AML)
Blood·2025
Chronic myeloid leukemia (CML) evolution is not encoded in single-cell microstates, but emerges from population-level macrostates
Blood·2025Open Access
Abstract B065: Loss of SMARCA4 leads to intron retention and generation of tumor-associated antigens in small cell carcinoma of the ovary, hypercalcemic type
Cancer Research·2025· 1 cited
Challenges in the return of molecular tumor profiling results
JNCI Journal of the National Cancer Institute·2025
Supplementary Tables from Loss of SMARCA4 Leads to Intron Retention and Generation of Tumor-Associated Antigens in Small Cell Carcinoma of the Ovary, Hypercalcemic Type
2025Open Access
Supplementary Materials from Loss of SMARCA4 Leads to Intron Retention and Generation of Tumor-Associated Antigens in Small Cell Carcinoma of the Ovary, Hypercalcemic Type
2025Open Access
Data from Loss of SMARCA4 Leads to Intron Retention and Generation of Tumor-Associated Antigens in Small Cell Carcinoma of the Ovary, Hypercalcemic Type
2025Open Access
Optimizing participant and community engagement in cancer genomic sequencing research
Genetics in Medicine·2025Open Access
A Concordance Study among 26 NGS Laboratories Participating in the NCI Molecular Analysis for Therapy Choice Clinical Trial
Clinical Cancer Research·2025Open Access
Long-term clinical outcomes with nivolumab/ipilimumab with or without <i>Clostridium butyricum</i> MIYAIRI588 in metastatic renal cell carcinoma (mRCC): A randomized phase Ib clinical trial.
Journal of Clinical Oncology·2025· 1 cited
Loss of SMARCA4 Leads to Intron Retention and Generation of Tumor-Associated Antigens in Small Cell Carcinoma of the Ovary, Hypercalcemic Type
Cancer Research·2025· 2 citedOpen Access
Abstract 4562: Bespoke sequencing of enriched and normalized amplicons increases on-target rate and reduces background noise for circulating tumor DNA detection and quantification
Cancer Research·2025· 1 cited
Feasibility of enriched amplicon circulating tumor DNA sequencing to detect minimal residual disease (MRD) after prostatectomy in localized prostate cancer.
Journal of Clinical Oncology·2025· 2 cited
Cabozantinib (cabo) and nivolumab (nivo) with or without CBM588 in patients with metastatic renal cell carcinoma: Updated clinical outcomes of a phase I study.
Journal of Clinical Oncology·2025· 1 cited
miR-142 deficit in T cells during blast crisis promotes chronic myeloid leukemia immune escape
Nature Communications·2025· 2 citedOpen Access
Super-enhancers and efficacy of triptolide in small cell carcinoma of the ovary hypercalcemic type
iScience·2025· 2 citedOpen Access
Predicting Individual Responses in Phase I Oncology Trials Using Routinely Collected Clinical Biomarkers
2024Open Access
77 Impact of CBM588 on gut microbiome composition and dysbiosis in patients receiving frontline immune checkpoint inhibitor (ICI) combinations for metastatic renal cell carcinoma (mRCC)
The Oncologist·2024Open Access
72 Impact of microbiome modulation on serum cytokine profile in a randomized, phase I trial of cabozantinib/nivolumab (cabo/nivo) with or without CBM588 in pts with metastatic renal cell carcinoma (mRCC)
The Oncologist·2024Open Access
Re-expression of SMARCA4/BRG1 in Small Cell Carcinoma of Ovary, Hypercalcemic Type (SCCOHT) promotes an epithelial-like gene signature through an AP-1-dependent mechanism
UNC Libraries·2024Open Access
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Frequent Co-authors

Michael Bittner(13), Paul S. Meltzer(13), John D. Carpten(8), Joan E. Bailey‐Wilson(6), Olli Kallioniemi(5), Raman Sood(4), Charles M. Ewing(4), Yidong Chen(4), Sally A. Amundson(4), Albert J. Fornace(4), Kenneth W. Kinzler(3), Bert Vogelstein(3), Sarah D. Isaacs(3), G. Steven Bova(3), Piroska Bujnovszky(3), William B. Isaacs(3), Christiane M. Robbins(3), Elizabeth M. Gillanders(3), Henry F. McFarland(3), Javed Khan(3)