Albert J. Fornace

Georgetown University — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

110h-index43.9kcitations531works2.82yr avg
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Research Topics

DNA Repair Mechanisms(124), Cancer-related Molecular Pathways(124), Effects of Radiation Exposure(112), Carcinogens and Genotoxicity Assessment(67), Metabolomics and Mass Spectrometry Studies(66)

Publications530 total

Dose and LET-dependence of gastric cancer risk in Apc1638N/+ mice exposed to space-relevant radiation types
Life Sciences in Space Research·2026Open Access
Elevated SASP Factors, Reduced Antioxidant Enzymes, and Increased Tumor Susceptibility in Space Radiation-Exposed ApcMin/+ Mice
International Journal of Molecular Sciences·2025Open Access
A human 3D culture-organ-on-chip platform for investigating the tumor microenvironment response to ionizing radiation
iScience·2025· 1 citedOpen Access
cGAS/STING Pathway Mediates Accelerated Intestinal Cell Senescence and SASP After GCR Exposure in Mice
Cells·2025· 1 citedOpen Access
Effects of Combined Bacterial Infection and Radiation Injury on Biofluid Metabolite Profiles in the Murine Model
ACS Omega·2025Open Access
TGx-DDI (toxicogenomic DNA damage-inducing) biomarker validation: multi-site ring trial supporting regulatory use
Toxicological Sciences·2025Open Access
Multicentered Biospecimen Analyses after 4 Gy Sublethal Total Body Irradiation in Rhesus Macaques
Radiation Research·2025Open Access
Radiation Quality-Dependent Progressive Increase in Oxidative DNA Damage and Intestinal Tumorigenesis in Apc1638N/+ Mice
Current Oncology·2025· 4 citedOpen Access
Sex Differences in Urinary Metabolite Profiles between Survivors and Non-Survivors of Radiation-induced Lung Injury in the C57L/J Murine Model
Radiation Research·2025· 1 cited
Senolytic agent ABT-263 mitigates low- and high-LET radiation-induced gastrointestinal cancer development in Apc1638N/+ mice
Aging·2025· 7 citedOpen Access
Simulated Galactic Cosmic Radiation Exposure-Induced Mammary Tumorigenesis in ApcMin/+ Mice Coincides with Activation of ERα-ERRα-SPP1 Signaling Axis
Cancers·2024· 7 citedOpen Access
Long-term Radiation Signal Persistence in Urine and Blood: A Two-year Analysis in Non-human Primates Exposed to a 4 Gy Total-Body Gamma-Radiation Dose
Radiation Research·2024
Effects of High-Linear-Energy-Transfer Heavy Ion Radiation on Intestinal Stem Cells: Implications for Gut Health and Tumorigenesis
Cancers·2024· 3 citedOpen Access
8-OxodG: A Potential Biomarker for Chronic Oxidative Stress Induced by High-LET Radiation
DNA·2024· 12 citedOpen Access
Impact of Partial Body Shielding from Very High Dose Rates on Untargeted Metabolomics in Biodosimetry
ACS Omega·2024· 6 citedOpen Access
p16 <sup>High</sup> immune cell - controlled disease tolerance as a broad defense and healthspan extending strategy
2024· 5 citedOpen Access
Host microbiome depletion attenuates biofluid metabolite responses following radiation exposure
PLoS ONE·2024· 4 citedOpen Access
How We Got Here: One Laboratory's Odyssey in the Field of Radiation-Inducible Genes
Radiation Research·2024
Expression of Stem Cell Markers in High-LET Space Radiation-Induced Intestinal Tumors in Apc1638N/+ Mouse Intestine
Cancers·2023· 7 citedOpen Access
Impact of GADD45A on Radiation Biodosimetry Using Mouse Peripheral Blood
Radiation Research·2023· 3 citedOpen Access
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Frequent Co-authors

Sally A. Amundson(10), M. Christine Hollander(7), Qimin Zhan(7), Dmitry V. Bulavin(7), Ettore Appella(6), France Carrier(5), Timothy G. Myers(5), P M O'Connor(5), Kurt W. Kohn(5), John N. Weinstein(4), Dominic A. Scudiero(4), Michael B. Kastan(4), Isaac Alamo(4), Carl W. Anderson(4), Jeffrey M. Trent(4), Wafik S. El‐Deiry(3), I Bae(3), Saijun Fan(3), Dan A. Liebermann(3), Michael J. Antinore(3)