Weiru Wang

Beijing University of Technology — China

Biochemistry, Genetics and Molecular Biology · Life Sciences

42h-index10.4kcitations167works4.12yr avg
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Research Topics

Melanoma and MAPK Pathways(28), Monoclonal and Polyclonal Antibodies Research(19), Chemokine receptors and signaling(19), Protein Kinase Regulation and GTPase Signaling(18), Biochemical and Molecular Research(17)

Publications166 total

Structural basis for DCAF2 as a novel E3 ligase for PROTAC-mediated targeted protein degradation
Structure·2025· 3 cited
Integrating Hydrogen Exchange with Molecular Dynamics for Improved Ligand Binding Predictions
Journal of Chemical Information and Modeling·2025· 3 cited
Multi-AGV Dynamic Path Planning Method for Warehouse Logistics
2025
Abstract 3787: Restoring the function of the guardian of the genome: FMC-220 a highly potent and selective covalent activator of p53 Y220C
Cancer Research·2025
Blockchain enabled policy-based access control mechanism to restrict unauthorized access to electronic health records
PeerJ Computer Science·2025· 6 citedOpen Access
Integrating Hydrogen Exchange with Molecular Dynamics for Improved Ligand Binding Predictions
2025Open Access
Discovery of GNE-6893, a Potent, Selective, Orally Bioavailable Small Molecule Inhibitor of HPK1
ACS Medicinal Chemistry Letters·2024· 12 citedOpen Access
Discovery of Potent, Selective, and Orally Available IRE1α Inhibitors Demonstrating Comparable PD Modulation to IRE1 Knockdown in a Multiple Myeloma Model
Journal of Medicinal Chemistry·2024· 7 citedOpen Access
HPK1 citron homology domain regulates phosphorylation of SLP76 and modulates kinase domain interaction dynamics
Nature Communications·2024· 11 citedOpen Access
The clinical applications of D-type parastomal hernia repair surgery
Hernia·2024
Combined Wind-Storage Frequency Modulation Control Strategy Based on Fuzzy Prediction and Dynamic Control
Energy Engineering·2024· 3 citedOpen Access
Enhancing Security and Privacy in Healthcare: A Conceptual Model
2023· 5 cited
Utilizing hydrogen exchange measurements to drive small molecules into cryptic protein binding sites
Acta Crystallographica Section A Foundations and Advances·2023Open Access
Analysis of Plasma Metabolomics of Liver Fibrosis Based on Bioinformatics
Medical Research Frontiers·2023Open Access
Abstract 1142: Discovery of FMC-376 a novel orally bioavailable inhibitor of activated KRASG12C
Cancer Research·2023· 16 cited
Supplementary Figure 6 from Development and Preclinical Characterization of a Humanized Antibody Targeting CXCL12
2023Open Access
Supplementary Tables 1-6 from ERK Mutations and Amplification Confer Resistance to ERK-Inhibitor Therapy
2023Open Access
Supplementary Figure 4 from Development and Preclinical Characterization of a Humanized Antibody Targeting CXCL12
2023Open Access
Supplementary Figure 2 from Development and Preclinical Characterization of a Humanized Antibody Targeting CXCL12
2023Open Access
Data from ERK Mutations and Amplification Confer Resistance to ERK-Inhibitor Therapy
2023Open Access
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Frequent Co-authors

Angela Oh(9), Joachim Rudolph(9), Bijay S. Jaiswal(7), Zora Modrušan(7), Somasekar Seshagiri(7), Sung‐Hou Kim(6), Frédéric J. de Sauvage(6), John G. Moffat(6), Adhirai Marimuthu(5), Hoa Nguyen(5), Brian L. West(5), Jian Wu(5), Rosalind Kim(5), Thomas O’Brien(5), Xiaozhang Zheng(5), Yen‐Ching Ho(5), Peter S. Dragovich(5), Mark Zak(5), Po‐wai Yuen(5), Ben Powell(4)