Nywana Sizemore

Biochemistry, Genetics and Molecular Biology · Life Sciences

21h-index2.9kcitations35works0.02yr avg
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Research Topics

NF-κB Signaling Pathways(12), Cytokine Signaling Pathways and Interactions(10), PI3K/AKT/mTOR signaling in cancer(6), Immune Response and Inflammation(5), Cervical Cancer and HPV Research(4)

Publications35 total

A Raf-independent Epidermal Growth Factor Receptor Autocrine Loop Is Necessary for Ras Transformation of Rat Intestinal Epithelial Cells
UNC Libraries·2021Open Access
BRMS1 contributes to the negative regulation of uPA gene expression through recruitment of HDAC1 to the NF-κB binding site of the uPA promoter
Clinical & Experimental Metastasis·2009· 48 citedOpen Access
Mutated in colorectal cancer, a putative tumor suppressor for serrated colorectal cancer, selectively represses β-catenin-dependent transcription
Oncogene·2008· 94 citedOpen Access
Activation of a Subset of Genes by IFN- <i>γ</i> Requires IKK <i>β</i> but Not Interferon-Dependent Activation of NF- <i>κ</i> B
Journal of Interferon & Cytokine Research·2007· 18 cited
Podocalyxin Increases the Aggressive Phenotype of Breast and Prostate Cancer Cells <i>In vitro</i> through Its Interaction with Ezrin
Cancer Research·2007· 145 cited
Interleukin-1 (IL-1)-induced TAK1-dependent Versus MEKK3-dependent NFκB Activation Pathways Bifurcate at IL-1 Receptor-associated Kinase Modification
Journal of Biological Chemistry·2006· 116 citedOpen Access
Role of IKK and oscillatory NFκB kinetics in MMP‐9 gene expression and chemoresistance to 5‐fluorouracil in RKO colorectal cancer cells
Molecular Carcinogenesis·2006· 45 cited
Novel enhanced lung-colonizing variant of murine MBT-2 bladder cancer cells
Urology·2005· 4 cited
Breast Cancer Metastasis Suppressor 1 Inhibits Gene Expression by Targeting Nuclear Factor-κB Activity
Cancer Research·2005· 114 citedOpen Access
The AKT/IκB kinase pathway promotes angiogenic/metastatic gene expression in colorectal cancer by activating nuclear factor-κB and β-catenin
Oncogene·2004· 181 cited
Inhibitor of κB kinase is required to activate a subset of interferon γ-stimulated genes
Proceedings of the National Academy of Sciences·2004· 57 citedOpen Access
Role of PI3K/AKT/IKK pathway in NFκB- and β-catenin- dependent transcription in colorectal cancer
Cancer Research·2004
Mutant human cells with constitutive activation of NF-κB
Proceedings of the National Academy of Sciences·2003· 21 citedOpen Access
Reciprocal Modulation of Toll-like Receptor-4 Signaling Pathways Involving MyD88 and Phosphatidylinositol 3-Kinase/AKT by Saturated and Polyunsaturated Fatty Acids
Journal of Biological Chemistry·2003· 512 citedOpen Access
Requirement of Phosphoinositide 3-Kinase and Akt for Interferon-β-mediated Induction of the β-R1(SCYB11) Gene
Journal of Biological Chemistry·2002· 39 citedOpen Access
Distinct Roles of the IκB Kinase α and β Subunits in Liberating Nuclear Factor κB (NF-κB) from IκB and in Phosphorylating the p65 Subunit of NF-κB
Journal of Biological Chemistry·2002· 384 citedOpen Access
A Role for NF-κB in the Induction of β-R1 by Interferon-β
Journal of Biological Chemistry·2001· 20 citedOpen Access
A Role for NF- Bi n the Induction of -R1 by Interferon-*
2001
Pharmacological inhibition of Ras-transformed epithelial cell growth is linked to down-regulation of epidermal growth factor–related peptides
Gastroenterology·1999· 42 cited
Activation of Phosphatidylinositol 3-Kinase in Response to Interleukin-1 Leads to Phosphorylation and Activation of the NF-κB p65/RelA Subunit
Molecular and Cellular Biology·1999· 643 citedOpen Access
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Frequent Co-authors

Ellen A. Rorke(10), George R. Stark(8), Muzaffer Cicek(6), Graham Casey(6), Ryuichi Fukuyama(5), Natalia Lerner(4), Swati Sathe(4), Sean Oldham(4), Channing J. Der(4), Xiaoxia Li(4), Richard M. Ransohoff(4), Richard L. Eckert(4), M.R. Sandhya Rani(4), George I. Gorodeski(4), Anju Agarwal(3), Kingshuk Das(3), Kwok Peng Ng(3), Robert J. Coffey(3), Joseph DiDonato(3), Steven T. Sizemore(2)