John W. Barrett

Western University — Canada

Biochemistry, Genetics and Molecular Biology · Life Sciences

42h-index7.1kcitations206works5.42yr avg
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Research Topics

Virus-based gene therapy research(48), Head and Neck Cancer Studies(40), Herpesvirus Infections and Treatments(35), Poxvirus research and outbreaks(29), Viral Infectious Diseases and Gene Expression in Insects(18)

Publications206 total

NOTCH1 loss promotes chemo and radio-resistance in head and neck cancer
Oral Oncology·2025
Oncological and functional outcomes of salvage surgery for local oropharyngeal cancer recurrence after primary Radiation±Chemotherapy
Surgical Oncology·2025
UNDERSTANDING AND OVERCOMING INNATE AND ACQUIRED MAPK-INHIBITION RESISTANCE IN ANAPLASTIC THYROID CANCER
Radiotherapy and Oncology·2025
Comparative analysis of patient-derived organoids and patient-derived xenografts as avatar models for predicting response to anti-cancer therapy
2025· 1 citedOpen Access
NOVEL INSIGHTS IN ADVANCED THYROID CARCINOMA: FROM MECHANISMS TO TREATMENTS: Molecular insights into the origin, biology, and treatment of anaplastic thyroid carcinoma
European Thyroid Journal·2025· 6 citedOpen Access
Molecular features of T and N stage progression in laryngeal cancer
Oral Oncology·2025· 3 citedOpen Access
Cohort-level clinical trajectory and molecular landscape of idiopathic subglottic stenosis for precision laryngology—a study of the Canadian Airways Research (CARE) group
EBioMedicine·2025· 5 citedOpen Access
Understanding and overcoming innate and acquired MAPK-inhibition resistance in anaplastic thyroid cancer
2024· 2 citedOpen Access
Core Modifications of GSK3335103 toward Orally Bioavailable α<sub>v</sub>β<sub>6</sub> Inhibitors with Improved Synthetic Tractability
Journal of Medicinal Chemistry·2024· 4 cited
Loss of MACROD2 drives radioresistance but not cisplatin resistance in HPV-positive head and neck cancer
Oral Oncology·2024· 2 citedOpen Access
Discovery and Development of Highly Potent and Orally Bioavailable Nonpeptidic α<sub>v</sub>β<sub>6</sub> Integrin Inhibitors
Journal of Medicinal Chemistry·2024· 1 cited
Outcomes for potentially Resectable patients undergoing primary chemoradiation treatment for <scp>T1</scp>–<scp>T2 HPV</scp> Negative oropharyngeal squamous cell carcinoma
Head & Neck·2024
Abstract 3580: Understanding and overcoming innate and acquired resistance to type I and II RAF inhibitors in anaplastic thyroid cancer using translational functional genomics
Cancer Research·2024
Abstract 1377: The role of TIM3 and PD1 blockades in head and neck cancer
Cancer Research·2024
The genomic and evolutionary landscapes of anaplastic thyroid carcinoma
Cell Reports·2024· 60 citedOpen Access
Personalized Treatment of Recurrent, Metastatic Head and Neck Cancer Guided by Patient-Derived Xenograft Models
Cureus·2024· 2 citedOpen Access
A comparison of timing and patterns of treatment failure, and survival outcomes after progression between <scp>HPV</scp>+ and <scp>HPV</scp>− patients undergoing chemoradiation for oropharyngeal squamous cell carcinomas
Head & Neck·2023· 3 citedOpen Access
HPV16 Intratypic Variants in Head and Neck Cancers: A North American Perspective
Viruses·2023· 6 citedOpen Access
<scp>HPV</scp>‐negative head and neck cancers with adverse pathological features carry specific molecular changes that are associated with survival
Head & Neck·2023· 2 citedOpen Access
Clinical Presentation and Genomic Analysis of HPV-Related Squamous Cell Carcinoma of the Larynx in Two Young Female Patients
Cureus·2023· 1 citedOpen Access
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Frequent Co-authors

Grant McFadden(29), Joe S. Mymryk(12), Anthony C. Nichols(12), David A. Palma(7), John Yoo(7), James Koropatnick(6), Kevin Fung(6), James B. Johnston(5), Steven H. Nazarian(5), Sandeep Dhaliwal(5), Gen Wang(5), Marianne M. Stanford(5), Xiujuan Gao(5), John C. Bell(5), Eric Winquist(5), Jason Franklin(5), Helen Everett(4), Cheryl Cameron(4), Steven J. Werden(4), Farhad Ghasemi(4)