John Lowe

Central and North West London NHS Foundation Trust — United Kingdom

Chemistry · Physical Sciences

48h-index8.2kcitations1.0kworks0.22yr avg
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Research Topics

Various Chemistry Research Topics(83), Genetics, Bioinformatics, and Biomedical Research(72), Computational Drug Discovery Methods(69), Receptor Mechanisms and Signaling(65), Neuropeptides and Animal Physiology(48)

Publications1.0k total

The future of psychiatry training in the UK – preparing for integrated care in a digital world
International Review of Psychiatry·2025
Growing from Our Roots: Strategies for Developing Culturally Grounded Health Promotion Interventions in American Indian, Alaska Native, and Native Hawaiian Communities
UNC Libraries·2025Open Access
Methods of Estimating Toxic Equivalents for Polychlorinated Dibenzodioxins and Dibenzofurans
2024
Defining the optimal spirometry cut-off points for optimal bronchodilator response in prematurity associated lung disease
2024
Challenges of modulating the risk of bronchopulmonary dysplasia in clinical trials – Authors' reply
The Lancet Respiratory Medicine·2024Open Access
POS0508 WHAT FACTORS ARE ASSOCIATED WITH PAIN INTENSITY IN AXIAL SPONDYLOARTHRITIS? RESULTS FROM THE INTERNATIONAL MAP OF AXIAL SPONDYLOARTHRITIS (IMAS)
Annals of the Rheumatic Diseases·2024· 2 cited
Faculty Opinions recommendation of Development of Potent Mcl-1 Inhibitors: Structural Investigations on Macrocycles Originating from a DNA-Encoded Chemical Library Screen.
Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature·2024
Faculty Opinions recommendation of Microcycle: an integrated and automated platform to accelerate drug discovery.
Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature·2024
Interventions for substance use disorders in American Indian/Alaska Native communities.
American Psychological Association eBooks·2024
Faculty Opinions recommendation of Identification of LY3522348: A highly selective and orally efficacious ketohexokinase inhibitor.
Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature·2023
Faculty Opinions recommendation of Discovery of a First-in-Class Small-Molecule Ligand for WDR91 Using DNA-Encoded Chemical Library Selection Followed by Machine Learning.
Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature·2023
Faculty Opinions recommendation of Discovery of KB-0742, a Potent, Selective, Orally Bioavailable Small Molecule Inhibitor of CDK9 for MYC-Dependent Cancers.
Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature·2023
MY CAREER IN MEDICINAL CHEMISTRY
Medicinal chemistry reviews·2023
Faculty Opinions recommendation of Transaminases provide key chiral building blocks for the synthesis of selective M1/M4 agonists.
Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature·2023
Faculty Opinions recommendation of Leveraging Ligand Affinity and Properties: Discovery of Novel Benzamide-Type Cereblon Binders for the Design of PROTACs.
Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature·2023
Faculty Opinions recommendation of Synthesis and Conformational Analysis of FR901464-Based RNA Splicing Modulators and Their Synergism in Drug-Resistant Cancers.
Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature·2023
Faculty Opinions recommendation of Discovery of MK-1468: A Potent, Kinome-Selective, Brain-Penetrant Amidoisoquinoline LRRK2 Inhibitor for the Potential Treatment of Parkinson's Disease.
Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature·2023
Faculty Opinions recommendation of Prediction of Small-Molecule Developability Using Large-Scale In Silico ADMET Models.
Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature·2023
Faculty Opinions recommendation of Discovery of a 53BP1 Small Molecule Antagonist Using a Focused DNA-Encoded Library Screen.
Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature·2023
Faculty Opinions recommendation of Recording Binding Information Directly into DNA-Encoded Libraries Using Terminal Deoxynucleotidyl Transferase.
Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature·2023
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Frequent Co-authors

R. Michael Snider(6), Billy R. Martin(6), Susan E. Drozda(5), Thomas Seeger(4), Stevin H. Zorn(4), Kelly P. Longo(3), Mario D. Aceto(3), Anne W. Schmidt(3), Stafford McLean(3), Dianne K. Bryce(3), Thue W. Schwartz(3), Sandra P. Welch(3), Jean Morrone(3), Mauricio Maia(3), Lorraine A. Lebel(2), Harry Howard(2), James Heym(2), Ulrik Gether(2), Susan M. Scates(2), Stacie A. Cook(2)