Thue W. Schwartz

University of Copenhagen — Denmark

Biochemistry, Genetics and Molecular Biology · Life Sciences

98h-index35.4kcitations497works10.62yr avg
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Research Topics

Receptor Mechanisms and Signaling(169), Neuropeptides and Animal Physiology(167), Pancreatic function and diabetes(70), Diabetes Treatment and Management(58), Regulation of Appetite and Obesity(45)

Publications496 total

Thromboxane signalling links immune activation to enhanced glucose uptake in skeletal muscle
Diabetologia·2026Open Access
Identification of human gut bacteria that produce bioactive serotonin and promote colonic innervation
Cell Reports·2025· 1 citedOpen Access
Neuropeptide Y receptors in GtoPdb v.2025.3
IUPHAR/BPS Guide to Pharmacology CITE·2025Open Access
Intracrine FFA4 signaling controls lipolysis at lipid droplets
Nature Chemical Biology·2025· 1 citedOpen Access
Shaping the future of cardiometabolic innovation: advances and opportunities
Nature Metabolism·2025· 3 cited
Constitutive activation and allosteric mechanisms underlying Gi/Gq signaling bias in SUCNR1 revealed by AlphaFold-based modeling and enhanced sampling simulations
2025Open Access
Challenging activity and signaling bias in tachykinin NK1 and NK2 receptors by truncated neuropeptides
Journal of Biological Chemistry·2025· 3 citedOpen Access
Neurons Co-Expressing GLP-1, CCK, and PYY Receptors Particularly in Right Nodose Ganglion and Innervating Entire GI Tract in Mice
International Journal of Molecular Sciences·2025· 8 citedOpen Access
Transcriptomic signatures of cold acclimated adipocytes reveal CXCL12 as a Brown autocrine and paracrine chemokine
Molecular Metabolism·2025· 6 citedOpen Access
Degradation Of Pancreatic Polypeptide — A Peptide Hormone With A Globular Structure In Aqueous Solution
2024· 1 cited
NK2R control of energy expenditure and feeding to treat metabolic diseases
Nature·2024· 37 citedOpen Access
Molecular determinants of neuropeptide-mediated activation mechanisms in tachykinin NK1 and NK2 receptors
Journal of Biological Chemistry·2024· 1 citedOpen Access
An atlas of GPCRs in dopamine neurons: Identification of the free fatty acid receptor 4 as a regulator of food and water intake
Cell Reports·2024· 4 citedOpen Access
Multiple recent HCAR2 structures demonstrate a highly dynamic ligand binding and G protein activation mode
Nature Communications·2024· 14 citedOpen Access
GLP-1-directed NMDA receptor antagonism for obesity treatment
Nature·2024· 74 citedOpen Access
Molecular dynamics-based identification of binding pathways and two distinct high-affinity sites for succinate in succinate receptor 1/GPR91
Molecular Cell·2024· 17 citedOpen Access
Lactate receptor GPR81 drives breast cancer growth and invasiveness through regulation of ECM properties and Notch ligand DLL4
BMC Cancer·2023· 25 citedOpen Access
Deciphering specificity and cross-reactivity in tachykinin NK1 and NK2 receptors
Journal of Biological Chemistry·2023· 6 citedOpen Access
G-Protein-Coupled Receptor 91-Dependent Signalling Does Not Influence Vascular Inflammation and Atherosclerosis in Hyperlipidaemic Mice
Cells·2023· 3 citedOpen Access
A new paradigm of intracrine free fatty acid receptor 4 signaling at lipid droplets
2023· 3 citedOpen Access
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Frequent Co-authors

Mette M. Rosenkilde(10), Birgitte Holst(9), Jens J. Holst(7), Kristoffer L. Egerod(7), Anna Sofie Husted(5), Maja S. Engelstoft(5), Mark K. Nøhr(4), Jeffrey M. Zigman(3), Timothy N. C. Wells(3), M. Hauge(3), Stefan Offermanns(3), Thomas M. Frimurer(3), S L Jensen(3), Timo D. Müller(2), David A. D’Alessio(2), Harvey J. Grill(2), Diego Pérez–Tilve(2), Randy J. Seeley(2), M. Tschöp(2), Annette G. Beck‐Sickinger(2)