Jens J. Holst

University of Copenhagen — Denmark

Medicine · Health Sciences

193h-index159.1kcitations2.7kworks6.52yr avg
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Research Topics

Diabetes Treatment and Management(1173), Pancreatic function and diabetes(640), Diet and metabolism studies(582), Diabetes Management and Research(361), Metabolism, Diabetes, and Cancer(302)

Publications2.7k total

Physical Fitness with Exercise and GLP-1 Receptor Agonist Treatment Alone or Combined After Diet-Induced Weight Loss: A Secondary Analysis of a Randomized Controlled Trial in Adults with Obesity
Sports Medicine·2026Open Access
Repurposing glucagon-like peptide-1 receptor agonists for the treatment of neurodegenerative disorders
Nature Aging·2025
Empagliflozin improves beta cell function independently of relief of glucotoxicity in patients with type 2 diabetes: results from a randomised cross-over study with insulin as comparator
Diabetologia·2025Open Access
Semaglutide and Early-Stage Metabolic Abnormalities in Individuals With Schizophrenia Spectrum Disorders
JAMA Psychiatry·2025· 2 citedOpen Access
<scp>GLP</scp> ‐2 and <scp>GIP</scp> acutely increase superior mesenteric artery blood flow in male rats, and the effect is independent of nitric oxide and vasoactive intestinal peptide
Physiological Reports·2025Open Access
GLP‐1 Receptor Agonists for the Prevention of New‐Onset Heart Failure: A Systematic Review and Meta‐Analysis of Placebo‐Controlled Randomized Clinical Trials
Obesity Reviews·2025Open Access
Influence of Diets Differing in Macronutrient Composition on Metabolic Regulation During Exercise in Adults with Type 1 Diabetes
Nutrients·2025Open Access
2′-Fucosyllactose supplementation results in a transient improvement in gut microbial resilience after vancomycin use in adults with overweight or obesity: a randomized, double-blind, placebo-controlled intervention
Gut Microbes·2025Open Access
Five years liraglutide treatment improves glucose tolerance in women with previous gestational diabetes mellitus—Results from a randomised controlled trial
Diabetes Obesity and Metabolism·2025
Identifying Multi-omics Signatures that characterize Responders to Plant-based Dietary Interventions
2025Open Access
HMGCR and Rosuvastatin Regulates GLP-1 Secretion and Expression—A Translational Study
The Journal of Clinical Endocrinology & Metabolism·2025· 1 citedOpen Access
In Vivo Inhibition of Dipeptidyl Peptidase 4 and Neprilysin Activity Enables Measurement of GLP-1 Secretion in Male Rats
Journal of the Endocrine Society·2025Open Access
Differential effects of Nordic and Vegetarian diets on lipid metabolism, gut microbiome and cardiometabolic risk factors: A multi-omic perspective from a randomized clinical intervention trial
2025Open Access
Pharmacological intervention: Challenges and promising outcomes for fat loss and preservation of lean body mass in the treatment of overweight and type 2 diabetes
Diabetes Obesity and Metabolism·2025Open Access
Glucagon acutely stimulates hepatic gluconeogenesis
Peptides·2025Open Access
Author response for "Pharmacological intervention: Challenges and promising outcomes for fat loss and preservation of lean body mass in the treatment of overweight and type 2 diabetes"
2025
Acute effects of <scp>GIP</scp> and <scp>GLP</scp> ‐1 receptor antagonism in totally pancreatectomized individuals: A randomized double‐blind, placebo‐controlled crossover study
Diabetes Obesity and Metabolism·2025· 1 cited
Artificial intelligence in metabolic research
Nature Metabolism·2025
Author response for "Acute effects of &lt;scp&gt;GIP&lt;/scp&gt; and &lt;scp&gt;GLP&lt;/scp&gt;‐1 receptor antagonism in totally pancreatectomized individuals: A randomized double‐blind, placebo‐controlled crossover study"
2025
Prevention of type 2 diabetes through prediabetes remission without weight loss
Nature Medicine·2025· 10 citedOpen Access
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Frequent Co-authors

Michael A. Nauck(9), Cathrine Ørskov(9), Carolyn F. Deacon(9), Sten Madsbad(7), Tina Vilsbøll(4), Thure Krarup(4), W. Creutzfeldt(3), Arne Astrup(3), Ellen E. Blaak(3), M. Gutniak(3), Bolette Hartmann(3), Markus M. Heimesaat(2), David A. D’Alessio(2), Juris J. Meier(2), Thue W. Schwartz(2), Mads Tang‐Christensen(2), Anne Flint(2), Jan Lysgaard Madsen(2), B. Willms(2), Ruud S. Kootte(2)