Birgitte Holst

University of Copenhagen — Denmark

Neuroscience · Life Sciences

52h-index9.9kcitations171works5.52yr avg
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Research Topics

Regulation of Appetite and Obesity(76), Receptor Mechanisms and Signaling(51), Biochemical Analysis and Sensing Techniques(49), Adipose Tissue and Metabolism(42), Neuropeptides and Animal Physiology(31)

Publications171 total

Exercise maintains LEAP2 levels after weight loss in females with obesity
iScience·2025Open Access
Ghrelin receptor in GtoPdb v.2025.3
IUPHAR/BPS Guide to Pharmacology CITE·2025Open Access
Renal Ghrelin-Family GPR39 Receptor and Urinary Concentrating Ability
Journal of the American Society of Nephrology·2025· 2 cited
Regulation of LEAP2 by insulin and glucagon in mice and humans
Cell Reports Medicine·2025· 7 citedOpen Access
Bone-marrow macrophage-derived GPNMB protein binds to orphan receptor GPR39 and plays a critical role in cardiac repair
Nature Cardiovascular Research·2024· 20 citedOpen Access
An atlas of GPCRs in dopamine neurons: Identification of the free fatty acid receptor 4 as a regulator of food and water intake
Cell Reports·2024· 4 citedOpen Access
Neprilysin activity is increased in metabolic dysfunction-associated steatotic liver disease and normalizes after bariatric surgery or GLP-1 therapy
iScience·2023· 5 citedOpen Access
SAT032 Circulating Neprilysin Activity Is Increased In Type 2 Diabetes And Fatty Liver Disease, And Reduces Following Bariatric Surgery And Liraglutide Therapy
Journal of the Endocrine Society·2023Open Access
Mouse model of atypical DAT deficiency syndrome uncovers dopamine dysfunction associated with parkinsonism and psychiatric disease
2023· 1 citedOpen Access
LEAP2 is associated with cardiometabolic markers but is unchanged by antidiabetic treatment in people with prediabetes
American Journal of Physiology-Endocrinology and Metabolism·2023· 13 citedOpen Access
PICK1-Deficient Mice Maintain Their Glucose Tolerance During Diet-Induced Obesity
Journal of the Endocrine Society·2023· 4 citedOpen Access
The dietary regulation of <scp>LEAP2</scp> depends on meal composition in mice
The FASEB Journal·2023· 15 citedOpen Access
Ghrelin receptor in GtoPdb v.2023.1
IUPHAR/BPS Guide to Pharmacology CITE·2023· 1 citedOpen Access
Increased meal-induced neurotensin response predicts successful maintenance of weight loss – Data from a randomized controlled trial
Metabolism·2023· 9 citedOpen Access
Ketone monoester increases circulating levels of <scp>LEAP2</scp> and decreases appetite in healthy men
Diabetes Obesity and Metabolism·2023· 8 citedOpen Access
Author response for "Ketone monoester increases circulating levels of &lt;scp&gt;LEAP2&lt;/scp&gt; and decreases appetite in healthy men"
2023
Initial Pharmacological Characterization of a Major Hydroxy Metabolite of PF-5190457: Inverse Agonist Activity of PF-6870961 at the Ghrelin Receptor
Journal of Pharmacology and Experimental Therapeutics·2023· 6 citedOpen Access
LEAP2 reduces postprandial glucose excursions and ad libitum food intake in healthy men
Cell Reports Medicine·2022· 70 citedOpen Access
Beta-Hydroxybutyrate Suppresses Hepatic Production of the Ghrelin Receptor Antagonist LEAP2
Endocrinology·2022· 30 citedOpen Access
Soluble SorCS1 binds the insulin receptor to enhance insulin sensitivity
Research Square (Research Square)·2022Open Access
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Frequent Co-authors

Thue W. Schwartz(33), Andreas Nygaard Madsen(13), Thomas M. Frimurer(9), Kristoffer L. Egerod(8), Christian Elling(8), Annette G. Beck‐Sickinger(6), Maja S. Engelstoft(6), Cecilia Ratner(5), Jens J. Holst(5), Anders Bach(4), Pia S. Petersen(4), Lars‐Ole Gerlach(3), Mette M. Rosenkilde(3), Rie Nygaard(3), Nicholas D. Holliday(3), Helen M. Cox(3), Erik Brandt(3), David P.D. Woldbye(3), Chunyu Jin(3), Manja Lang(3)