Antonio Lupia

University of Cagliari — Italy

Biochemistry, Genetics and Molecular Biology · Life Sciences

16h-index762citations47works4.52yr avg
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Research Topics

DNA and Nucleic Acid Chemistry(6), RNA Interference and Gene Delivery(4), Cytokine Signaling Pathways and Interactions(4), Synthesis and Catalytic Reactions(4), Enzyme function and inhibition(4)

Publications47 total

Exploring <i>Boswellia serrata</i> Triterpenes: A New Frontier in Leukemia Inhibitory Factor Receptor Modulation
ACS Omega·2025· 4 citedOpen Access
Synthesis and Evaluation of Thiazolidinone-Isatin Hybrids for Selective Inhibition of Cancer-Related Carbonic Anhydrases
ACS Medicinal Chemistry Letters·2025· 1 citedOpen Access
3D variability analysis reveals a hidden conformational change controlling ammonia transport in human asparagine synthetase
Nature Communications·2024· 5 citedOpen Access
Design, Synthesis, and Pharmacological Evaluation of Dual FXR-LIFR Modulators for the Treatment of Liver Fibrosis
Journal of Medicinal Chemistry·2024· 11 citedOpen Access
Exploring the 1-(4-Nitrophenyl)-3-arylprop-2-en-1-one Scaffold for the Selective Inhibition of Monoamine Oxidase B
ACS Medicinal Chemistry Letters·2024· 1 citedOpen Access
Privileged Scaffold Hybridization in the Design of Carbonic Anhydrase Inhibitors
Molecules·2024Open Access
New Structural Features of Isatin Dihydrothiazole Hybrids for Selective Carbonic Anhydrase Inhibitors
ACS Medicinal Chemistry Letters·2024· 4 citedOpen Access
A first-in-class Wiskott-Aldrich syndrome protein activator with anti-tumor activity in hematologic cancers
Haematologica·2024· 4 citedOpen Access
Su1492 BILE ACIDS AS ENDOGENOUS ANTAGONISTS OF LEUKEMIA INHIBITORY FACTOR RECEPTOR (LIFR) IN GASTRIC CANCER (GC): IMPLICATIONS FOR THERAPEUTIC INTERVENTIONS
Gastroenterology·2024
Bile acids serve as endogenous antagonists of the Leukemia inhibitory factor (LIF) receptor in oncogenesis
Biochemical Pharmacology·2024· 16 citedOpen Access
Exploring the DNA2-PNA heterotriplex formation in targeting the Bcl-2 gene promoter: A structural insight by physico-chemical and microsecond-scale MD investigation
Heliyon·2024· 3 citedOpen Access
The leukemia inhibitory factor regulates fibroblast growth factor receptor 4 transcription in gastric cancer
Cellular Oncology·2023· 16 citedOpen Access
Bile Acids Serve As Endogenous Antagonists Of The Leukemia Inhibitory Factor (LIF) Receptor in Oncogenesis
2023Open Access
Molecular and Structural Aspects of Clinically Relevant Mutations of SARS-CoV-2 RNA-Dependent RNA Polymerase in Remdesivir-Treated Patients
Pharmaceuticals·2023· 3 citedOpen Access
Representative structures of the energetic minima of bcl2midG4-ds/TF-PNA1K heterotriplex.
Zenodo (CERN European Organization for Nuclear Research)·2023Open Access
Representative structures of the energetic minima of bcl2midG4-ds/TF-PNA1K heterotriplex.
Zenodo (CERN European Organization for Nuclear Research)·2023Open Access
3D Variability Analysis Reveals a Hidden Conformational Change Controlling Ammonia Transport in Human Asparagine Synthetase
2023· 2 citedOpen Access
Su1416 NATURAL AND SYNTHETIC BILE ACIDS FUNCTION AS LEUKEMYA INHIBITORY FACTOR RECEPTOR (LIFR) ANTAGONISTS AND REVERT PROLIFERATION AND MIGRATION IN PANCREATIC CANCER CELL LINES
Gastroenterology·2023
Development of Cyclic Peptides Targeting the Epidermal Growth Factor Receptor in Mesenchymal Triple-Negative Breast Cancer Subtype
Cells·2023· 14 citedOpen Access
Discovery of BAR502, as potent steroidal antagonist of leukemia inhibitory factor receptor for the treatment of pancreatic adenocarcinoma
Frontiers in Oncology·2023· 18 citedOpen Access
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Frequent Co-authors

Federica Moraca(25), Stefano Alcaro(25), Bruno Catalanotti(16), Giosuè Costa(15), Roberta Rocca(15), Annalisa Maruca(11), Anna Artese(10), Raffaella Catalano(9), Isabella Romeo(9), Francesca Alessandra Ambrosio(9), Carmen Massa(9), Angela Zampella(9), Stefano Fiorucci(9), Francesco Ortuso(8), Cristina Di Giorgio(8), Martina Bordoni(8), Elva Morretta(8), Ginevra Urbani(8), Maria Chiara Monti(8), Michele Biagioli(8)