Francesca Alessandra Ambrosio

Magna Graecia University — Italy

Biochemistry, Genetics and Molecular Biology · Life Sciences

17h-index993citations50works2.72yr avg
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Research Topics

RNA and protein synthesis mechanisms(9), Computational Drug Discovery Methods(8), RNA Research and Splicing(7), SARS-CoV-2 and COVID-19 Research(6), Phytochemicals and Antioxidant Activities(4)

Publications50 total

Diospyros kaki leaf polyphenolic extract as a new edible source of anti-glycative agents: bioaccessibility and structure-activity relationship investigation
Food Research International·2026Open Access
Aloysia citrodora Polyphenolic Extract: From Anti-Glycative Activity to In Vitro Bioaccessibility and In Silico Studies
Nutrients·2025Open Access
In Silico-Guided Discovery and In Vitro Evaluation of Natural Sortase A Inhibitors to Fight Multidrug-Resistant <i>Staphylococcus aureus</i>
Journal of Medicinal Chemistry·2025
Rosmarinus officinalis L. as Fascinating Source of Potential Anticancer Agents Targeting Aromatase and COX-2: An Overview
Molecules·2025· 3 citedOpen Access
O-derivatization of natural tropolone and β-thujaplicin leading to effective inhibitors of human carbonic anhydrases IX and XII
European Journal of Medicinal Chemistry·2025· 2 citedOpen Access
Development of selective sigma-1 receptor ligands with antiallodynic activity: A focus on piperidine and piperazine scaffolds
European Journal of Medicinal Chemistry·2024· 4 citedOpen Access
Peptide Nucleic Acids in Saturation Transfer Difference Nuclear Magnetic Resonance Experiments: A Simple and Valuable Tool for Studying HuR–Small Molecule Complexes
ACS Omega·2024Open Access
Discovery of pyridoquinoxaline-based new P-gp inhibitors as coadjutant against Multi Drug Resistance in cancer
European Journal of Medicinal Chemistry·2024· 13 citedOpen Access
Neurodegeneration: can metabolites from Eremurus persicus help?
Frontiers in Pharmacology·2024· 2 citedOpen Access
New Insights for Polyphenolic Compounds as Naturally Inspired Proteasome Inhibitors
Pharmaceuticals·2023· 8 citedOpen Access
Identification of HuR–RNA Interfering Compounds by Dynamic Combinatorial Chemistry and Fluorescence Polarization
ACS Medicinal Chemistry Letters·2023· 10 citedOpen Access
Molecular and Structural Aspects of Clinically Relevant Mutations of SARS-CoV-2 RNA-Dependent RNA Polymerase in Remdesivir-Treated Patients
Pharmaceuticals·2023· 3 citedOpen Access
Discovery of AD258 as a Sigma Receptor Ligand with Potent Antiallodynic Activity
Journal of Medicinal Chemistry·2023· 8 citedOpen Access
Short- and Long-Term Regulation of HuD: A Molecular Switch Mediated by Folic Acid?
International Journal of Molecular Sciences·2023· 3 citedOpen Access
Targeting SARS-CoV-2 Main Protease: A Successful Story Guided by an <i>In Silico</i> Drug Repurposing Approach
Journal of Chemical Information and Modeling·2023· 14 citedOpen Access
<i>In Silico</i>-Guided Rational Drug Design and Synthesis of Novel 4-(Thiophen-2-yl)butanamides as Potent and Selective TRPV1 Agonists
Journal of Medicinal Chemistry·2023· 9 citedOpen Access
Synthesis, Computational Insights, and Evaluation of Novel Sigma Receptors Ligands
ACS Chemical Neuroscience·2023· 7 citedOpen Access
Natural Agents as Novel Potential Source of Proteasome Inhibitors with Anti-Tumor Activity: Focus on Multiple Myeloma
Molecules·2023· 16 citedOpen Access
Targeting SARS-CoV-2 nsp13 Helicase and Assessment of Druggability Pockets: Identification of Two Potent Inhibitors by a Multi-Site In Silico Drug Repurposing Approach
Molecules·2022· 11 citedOpen Access
From Nature to Synthetic Compounds: Novel 1(N),2,3 Trisubstituted-5-oxopyrrolidines Targeting Multiple Myeloma Cells
International Journal of Molecular Sciences·2022· 7 citedOpen Access
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Frequent Co-authors

Stefano Alcaro(41), Giosuè Costa(37), Anna Artese(20), Isabella Romeo(14), Simona Collina(12), Roberta Rocca(11), Daniela Rossi(10), Annalisa Maruca(9), Antonio Lupia(9), Federica Moraca(9), Raffaella Catalano(8), Francesca Ceccherini‐Silberstein(7), Donatella Bagetta(7), Francesco Ortuso(7), Francesca Vasile(7), Valentina Svicher(6), Romina Salpini(6), Carmine Talarico(6), Pasquale Linciano(6), Mohammad Alkhatib(5)