John W. Sedat

University of California, San Francisco — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

75h-index24.3kcitations222works1.82yr avg
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Research Topics

Genomics and Chromatin Dynamics(52), Advanced Fluorescence Microscopy Techniques(52), Advanced Electron Microscopy Techniques and Applications(48), Microtubule and mitosis dynamics(30), DNA and Nucleic Acid Chemistry(27)

Publications222 total

Deconvolution to restore cryo-EM maps with anisotropic resolution
2025Open Access
Deconvolution to restore cryo-EM maps with anisotropic resolution
2025· 4 citedOpen Access
Helical coiled nucleosome chromosome architectures during cell cycle progression
Proceedings of the National Academy of Sciences·2024· 3 citedOpen Access
Helical Coiled Nucleosome Chromosome Architectures during Cell Cycle Progression
2024Open Access
A proposed unified interphase nucleus chromosome structure: Preliminary preponderance of evidence
Proceedings of the National Academy of Sciences·2022· 13 citedOpen Access
A proposed unified mitotic chromosome architecture
Proceedings of the National Academy of Sciences·2022· 14 citedOpen Access
Microscope-Cockpit: Python-based bespoke microscopy for bio-medical science
Wellcome Open Research·2022· 8 citedOpen Access
Entropy-regularized deconvolution of cellular cryotransmission electron tomograms
Proceedings of the National Academy of Sciences·2021· 25 citedOpen Access
A Proposed Unified Mitotic Chromosome Architecture
2021· 2 citedOpen Access
A Proposed Unified Interphase Nucleus Chromosome Structure: Preliminary Preponderance of Evidence
2021· 4 citedOpen Access
Entropy Regularized Deconvolution of Cellular Cryo-Transmission Electron Tomograms
2021· 6 citedOpen Access
Microscope-Cockpit: Python-based bespoke microscopy for bio-medical science
Wellcome Open Research·2021· 15 citedOpen Access
Microscope-Cockpit: Python-based bespoke microscopy for bio-medical science
2021· 8 citedOpen Access
Three-dimensional deconvolution processing for STEM cryotomography
Proceedings of the National Academy of Sciences·2020· 34 citedOpen Access
3D Deconvolution Processing for STEM Cryo-Tomography
2020Open Access
CryoSIM: super-resolution 3D structured illumination cryogenic fluorescence microscopy for correlated ultrastructural imaging
Optica·2020· 90 citedOpen Access
CryoSIM: super resolution 3D structured illumination cryogenic fluorescence microscopy for correlated ultra-structural imaging
2020· 13 citedOpen Access
Supplementary document for CryoSIM: super resolution 3D structured illumination cryogenic fluorescence microscopy for correlated ultra-structural imaging - 4631682.pdf
Figshare·2020Open Access
On Bacterial and ØX-174 Messenger-RNA
CaltechTHESIS (California Institute of Technology)·2018Open Access
3D Deconvolution for Cryo-Scanning Transmission Electron Tomography
Microscopy and Microanalysis·2017Open Access
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Frequent Co-authors

David A. Agard(28), Wallace F. Marshall(7), Abby F. Dernburg(6), Michael B. Braunfeld(6), Mats G. Gustafsson(5), Peter M. Carlton(5), Andrew S. Belmont(5), Lin Shao(4), W. Zacheus Cande(4), Aaron F. Straight(4), Yasushi Hiraoka(4), Guy Servant(3), Orion D. Weiner(3), Henry R. Bourne(3), Andrew W. Murray(3), Jennifer C. Fung(3), Mark Hochstrasser(3), Yosef Gruenbaum(3), Sebastian Haase(2), Lukman Winoto(2)