David J. Mathre

California Institute of Technology — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

29h-index4.4kcitations93works0.02yr avg
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Research Topics

Chemical Synthesis and Analysis(27), Asymmetric Synthesis and Catalysis(22), Asymmetric Hydrogenation and Catalysis(20), Crystallization and Solubility Studies(18), X-ray Diffraction in Crystallography(14)

Publications93 total

I. The Disastereoselective Alkylation of Chiral 2-Oxazolidinone Imide Enolates. II. Efforts Directed Toward the Enantioselective Total Synthesis of Ferensimycin B
CaltechTHESIS (California Institute of Technology)·2019Open Access
2-Amino-3-methyl-1,1-diphenyl-1-butanol
Encyclopedia of Reagents for Organic Synthesis·2014
Tetrahydro-1-methyl-3,3-diphenyl-1<i>H</i>, 3<i>H</i>-pyrrolo[1,2-<i>c</i>][1,3,2]oxazaborole
Encyclopedia of Reagents for Organic Synthesis·2013
α,α-Diphenyl-2-pyrrolidinemethanol
Encyclopedia of Reagents for Organic Synthesis·2012
Lipid nanoparticle purification by Spin Centrifugation–Dialysis (SCD): A facile and high-throughput approach for small scale preparation of siRNA–lipid complexes
International Journal of Pharmaceutics·2011· 21 cited
Discovery of a Stable Molecular Complex of an API With HCl: A Long Journey to a Conventional Salt
Journal of Pharmaceutical Sciences·2008· 11 cited
Tetrahydro-1-methyl-3,3-diphenyl-1<i>H</i>, 3<i>H</i>-pyrrolo[1,2-<i>c</i>][1,3,2]oxazaborole
Encyclopedia of Reagents for Organic Synthesis·2007
Tetrahydro-1-methyl-3,3-diphenyl-1<i>H</i>, 3<i>H</i>-pyrrolo[1,2-<i>c</i>][1,3,2]oxazaborole
Encyclopedia of Reagents for Organic Synthesis·2007
CCDC 619263: Experimental Crystal Structure Determination
The Cambridge Structural Database·2007Open Access
Development of a pharmaceutical cocrystal of a monophosphate salt with phosphoric acid
Chemical Communications·2006· 92 cited
Applying Statistical Design of Experiments and Automation to the Rapid Optimization of Metal-Catalyzed Processes in Process Development
JALA Journal of the Association for Laboratory Automation·2005· 13 cited
Mechanistic Studies of Molybdenum‐Catalyzed Asymmetric Alkylation
ChemInform·2005
Adsorbent Screening for Metal Impurity Removal in Pharmaceutical Process Research
Organic Process Research & Development·2005· 240 cited
CCDC 259412: Experimental Crystal Structure Determination
The Cambridge Structural Database·2005Open Access
CCDC 259413: Experimental Crystal Structure Determination
The Cambridge Structural Database·2005Open Access
Highly Selective Synthesis of 2‐Substituted‐5‐hydroxy‐6‐oxo‐1,6‐dihydropyrimidine‐4‐carboxylic Acid Derivatives Using a Novel Protected Dihydroxyfumarate.
ChemInform·2004
New Insights into the Mechanism of Molybdenum‐Catalyzed Asymmetric Alkylation
ChemInform·2004· 1 cited
Crystal structure and surface properties of an investigational drug—A case study
International Journal of Pharmaceutics·2004· 20 cited
Mechanistic Studies of Molybdenum-Catalyzed Asymmetric Alkylation
ACS symposium series·2004· 2 cited
Highly selective synthesis of 2-substituted-5-hydroxy-6-oxo-1,6-dihydropyrimidine-4-carboxylic acid derivatives using a novel protected dihydroxyfumarate
Tetrahedron Letters·2004· 15 cited
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Frequent Co-authors

Edward J. J. Grabowski(11), Robert A. Reamer(11), Christopher J. Welch(8), Paul J. Reider(8), David A. Evans(5), David M. Tschaen(5), Peter G. Dormer(5), James M. McNamara(5), Jennifer R. Chilenski(5), Zhiguo J. Song(4), I. Shinkai(4), Joseph D. Armstrong(4), Yongkui Sun(4), David L. Hughes(4), Guo-Jie Ho(4), Michel Chartrain(4), Michael D. Ennis(3), Lyndon C. Xavier(3), Alan W. Douglas(3), Mark A. Huffman(3)