Lawrence Salkoff

Washington University in St. Louis — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

50h-index8.9kcitations108works0.02yr avg
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Research Topics

Ion channel regulation and function(71), Neurobiology and Insect Physiology Research(33), Cardiac electrophysiology and arrhythmias(25), Neuroscience and Neural Engineering(24), Neuroscience and Neuropharmacology Research(15)

Publications108 total

How the Blind Watchmaker messed around with potassium channels
The Journal of General Physiology·2025Open Access
BPS2025 - Biophysical properties of BK channelopathies in heterozygous conditions
Biophysical Journal·2025
Case Report: Targeted treatment by fluoxetine/norfluoxetine of a KCNC2 variant causing developmental and epileptic encephalopathy
Frontiers in Pharmacology·2025Open Access
BK channels of five different subunit combinations underlie the de novo KCNMA1 G375R channelopathy
The Journal of General Physiology·2023· 11 citedOpen Access
BK channels of five different subunit combinations underlie the <i>de novo</i> KCNMA1 G375R channelopathy
2021· 2 citedOpen Access
Coupling of Ca <sup>2+</sup> and voltage activation in BK channels through the αB helix/voltage sensor interface
Proceedings of the National Academy of Sciences·2020· 24 citedOpen Access
Coupling of Ca <sup>2+</sup> and voltage activation in BK channels through the αB helix/voltage sensor interface
2020Open Access
Sodium‐activated potassium channels moderate excitability in vascular smooth muscle
The Journal of Physiology·2019· 39 citedOpen Access
Oxytocin can regulate myometrial smooth muscle excitability by inhibiting the Na<sup>+</sup>‐activated K<sup>+</sup> channel, Slo2.1
The Journal of Physiology·2018· 46 citedOpen Access
Alpha-B Helix of the RCK1 Domain is a Shared Structural Element for Both Voltage and Calcium Activation of BK Channels
Biophysical Journal·2018Open Access
Membrane potential of human sperm is sensitive to external pH and intracellular Ca2
Dépôt institutionnel de l'Université libre de Bruxelles (Université Libre de Bruxelles)·2017
GABA-B Controls Persistent Na <sup>+</sup> Current and Coupled Na <sup>+</sup> -Activated K <sup>+</sup> Current
eNeuro·2017· 8 citedOpen Access
A genetic variant of the sperm-specific SLO3 K+ channel has altered pH and Ca2+ sensitivities
Journal of Biological Chemistry·2017· 46 citedOpen Access
Deletion of cytosolic gating ring decreases gate and voltage sensor coupling in BK channels
The Journal of General Physiology·2017· 37 citedOpen Access
Alpha-B Helix of RCK1 is a Major Transduction Pathway for Ca 2+ Activation of BK Channels
Biophysical Journal·2017Open Access
Deletion of Cytoplasmic Gating Ring Alters Voltage Dependent Activation of BK Channels
Biophysical Journal·2016· 1 citedOpen Access
SLO2 Channels Are Inhibited by All Divalent Cations That Activate SLO1 K+ Channels
Journal of Biological Chemistry·2016· 22 citedOpen Access
Blockade of ENaCs by amiloride induces c-Fos activation of the area postrema
Brain Research·2015· 4 citedOpen Access
A Novel Approach for Locating the Sites of Drug Action on BK Channels
Biophysical Journal·2015Open Access
SLO3 K+ Channels Control Calcium Entry through CATSPER Channels in Sperm
Journal of Biological Chemistry·2014· 98 citedOpen Access
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Frequent Co-authors

Aguan Wei(13), Alice Butler(12), Celia M. Santi(7), Manuel Covarrubias(6), Aguan Wei(5), Alex Yuan(5), Keith Baker(4), Alberto Darszon(4), Timothy Jegla(4), Robert J. Wyman(4), Susan Tsunoda(3), Michael L. Nonet(3), Matthew Schreiber(3), Mitsuyoshi Saito(3), Christopher J. Lingle(3), Claudia L. Treviño(3), James H. Thomas(3), Gonzalo Ferreira(2), Michael D. Pak(2), Zhao-Wen Wang(2)