Timothy Jegla

Pennsylvania State University — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

32h-index9.4kcitations71works3.82yr avg
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Research Topics

Ion channel regulation and function(34), Marine Invertebrate Physiology and Ecology(18), Neuroscience and Neuropharmacology Research(13), Cardiac electrophysiology and arrhythmias(13), Neurobiology and Insect Physiology Research(12)

Publications71 total

Tracing the origins of human voltage-gated K <sup>+</sup> channels: where they come from and what we lost along the way
2025Open Access
Neurite branching is associated with mixed microtubule polarity in sea anemone neurons
Journal of Experimental Biology·2025· 1 citedOpen Access
Apoplastic metabolomics reveals sugars as mesophyll messengers regulating guard cell ion transport under red light
Nature Plants·2025· 3 citedOpen Access
Ctenophores and parahoxozoans independently evolved functionally diverse voltage-gated K+ channels
The Journal of General Physiology·2025· 7 cited
Ctenophores and parahoxozoans independently evolved complex and functionally diverse sets of voltage-gated K <sup>+</sup> channels
2024Open Access
A broad survey of choanoflagellates revises the evolutionary history of the Shaker family of voltage-gated K <sup>+</sup> channels in animals
Proceedings of the National Academy of Sciences·2024· 13 citedOpen Access
How ciliate protozoans became the royalty of K+ channel diversity and what it might mean in terms of ciliate physiology
Biophysical Journal·2024Open Access
Phylogenetic and functional analyses of Comb Jelly Shaker K+ channels reveal independent evolution of voltage-gated K+ channel diversity
Biophysical Journal·2024
Functional analysis of ctenophore Shaker K+ channels: N-type inactivation in the animal roots
Biophysical Journal·2024· 10 citedOpen Access
Kv12-encoded K+ channels drive the day–night switch in the repetitive firing rates of SCN neurons
The Journal of General Physiology·2023· 16 citedOpen Access
Taxonomy and Evolution of Ion Channels
2023· 4 cited
Kv12-Encoded K <sup>+</sup> Channels Drive the Day-Night Switch in the Repetitive Firing Rates of SCN Neurons
2023· 3 citedOpen Access
Genome-Scale Analysis Reveals Extensive Diversification of Voltage-Gated K+ Channels in Stem Cnidarians
Genome Biology and Evolution·2023· 17 citedOpen Access
Principles of sensor-effector organization in six-transmembrane ion channels
2021Open Access
External Cd2+ and protons activate the hyperpolarization-gated K+ channel KAT1 at the voltage sensor
The Journal of General Physiology·2020· 2 citedOpen Access
What is the correct stoichiometry of Kv2.1:Kv6.4 heteromers?
Proceedings of the National Academy of Sciences·2020· 6 citedOpen Access
Cadmium and Protons Activate the Plant Hyperpolarization-gated K+ Channel KAT1 through a Conserved Binding Site in the Voltage Sensor Domain
Biophysical Journal·2020Open Access
Extracellular HEME Modulates Voltage-gating in CNBD Superfamily Cation Channels
Biophysical Journal·2020Open Access
Cytoskeletal and synaptic polarity of LWamide-like+ ganglion neurons in the sea anemone <i>Nematostella vectensis</i>
Journal of Experimental Biology·2020· 12 citedOpen Access
Family matters
eLife·2018· 2 citedOpen Access
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Frequent Co-authors

Lawrence Salkoff(6), Damian B. van Rossum(6), Xiaofan Li(6), Alan D. Wickenden(5), Benjamin T. Simonson(5), Ardem Patapoutian(4), Satchidananda Panda(4), P. Kay Wagoner(4), Melissa M. Rolls(4), Mark Q. Martindale(4), Aditya Pisupati(4), Bihan Chen(4), Andrea Peier(3), Sun Wook Hwang(3), Surendra Kumar Nayak(3), Christian Schmedt(3), Xiaofei Zhang(3), Fortunay Diatta(3), Michael J. Layden(3), Keith J. Mickolajczyk(3)