Andrea Peier

Merck & Co., Inc., Rahway, NJ, USA (United States) — United States

Neuroscience · Life Sciences

26h-index8.8kcitations54works11.32yr avg
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Research Topics

Neurobiology and Insect Physiology Research(6), Receptor Mechanisms and Signaling(6), Ion Channels and Receptors(6), Chemical Synthesis and Analysis(5), Sarcoma Diagnosis and Treatment(4)

Publications54 total

Promoting Secretion of Pathological Tau Species Using an Induced Proximity Platform That Engages the Autophagy Pathway
ACS Chemical Neuroscience·2025
Author Correction: Design-rules for stapled peptides with in vivo activity and their application to Mdm2/X antagonists
Nature Communications·2025Open Access
Design-rules for stapled peptides with in vivo activity and their application to Mdm2/X antagonists
Nature Communications·2024· 34 citedOpen Access
A high‐throughput microfluidic mechanoporation platform to enable intracellular delivery of cyclic peptides in cell‐based assays
Bioengineering & Translational Medicine·2023· 5 citedOpen Access
Author response for "A high‐throughput microfluidic mechanoporation platform to enable intracellular delivery of cyclic peptides in cell‐based assays"
2023
Design-Rules for Stapled Alpha-Helical Peptides with On-Target In Vivo Activity: Application to Mdm2/X dual antagonists
2023· 2 citedOpen Access
Discovery and Structure-Based Design of Macrocyclic Peptides Targeting STUB1
Journal of Medicinal Chemistry·2022· 15 cited
Discovery and Structure-Based Design of Macrocyclic Peptides Targeting STUB1
2021· 2 citedOpen Access
Discovery of cell active macrocyclic peptides with on-target inhibition of KRAS signaling
2021· 2 citedOpen Access
High-Throughput Screening to Identify Small Molecules That Selectively Inhibit APOL1 Protein Level in Podocytes
SLAS DISCOVERY·2021· 5 citedOpen Access
NanoClick: A High Throughput, Target-Agnostic Peptide Cell Permeability Assay
ACS Chemical Biology·2021· 57 cited
Discovery of cell active macrocyclic peptides with on-target inhibition of KRAS signaling
Chemical Science·2021· 31 citedOpen Access
Utilizing Designed Receptors Exclusively Activated by Designer Drug Chemogenetic Tools to Identify Beneficial G Protein–Coupled Receptor Signaling for Fibrosis
Journal of Pharmacology and Experimental Therapeutics·2020· 2 citedOpen Access
Molecular Profiling Reveals a Common Metabolic Signature of Tissue Fibrosis
Cell Reports Medicine·2020· 52 citedOpen Access
Live Cell Membranome cDNA Screen: A Novel Homogenous Live Cell Binding Assay to Study Membrane Protein-Ligand Interaction
SLAS DISCOVERY·2019· 2 citedOpen Access
Bioprinted 3D Primary Human Intestinal Tissues Model Aspects of Native Physiology and ADME/Tox Functions
iScience·2018· 150 citedOpen Access
Macrocyclic α helical peptide therapeutic modality: A perspective of learnings and challenges
Bioorganic & Medicinal Chemistry·2018· 62 cited
Molecular Profiling Reveals a Common Metabolic Signature of Tissue Fibrosis
SSRN Electronic Journal·2018· 1 citedOpen Access
Development of a neuromedin U–human serum albumin conjugate as a long‐acting candidate for the treatment of obesity and diabetes. Comparison with the PEGylated peptide
Journal of Peptide Science·2013· 29 cited
Abstract 119: LCAT Activation in Combination with the CETP Inhibitor Anacetrapib Results in Enhanced Cholesterol Efflux and a Favorable Lipid Profile in Dyslipidemic Hamsters
Arteriosclerosis Thrombosis and Vascular Biology·2013
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Frequent Co-authors

Anthony W. Partridge(11), Lan Ge(10), Aurelia M. Meloni(9), Charles W. Johannes(9), Christopher J. Brown(9), David P. Lane(9), Ruchia Duggal(8), Tomi K. Sawyer(7), Chandra Verma(7), Srinivasaraghavan Kannan(7), Brian Henry(7), Ardem Patapoutian(6), Avery A. Sandberg(6), Kaustav Biswas(6), Arun Chandramohan(6), Gina M. Story(5), Hung Yi Kristal Kaan(5), Yu‐Chi Juang(5), Tsz Ying Yuen(5), Brad Sherborne(5)