K Wehrly

National Institute of Allergy and Infectious Diseases — United States

Immunology and Microbiology · Life Sciences

38h-index7.0kcitations63works0.02yr avg
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Research Topics

HIV Research and Treatment(36), Virus-based gene therapy research(17), Monoclonal and Polyclonal Antibodies Research(14), Immune Cell Function and Interaction(13), HIV/AIDS Research and Interventions(8)

Publications63 total

Analysis of two monoclonal antibodies reactive with envelope proteins of murine retroviruses: One pan specific antibody and one specific for Moloney leukemia virus
Journal of Virological Methods·2014· 9 citedOpen Access
Neurovirulence of Polytropic Murine Retrovirus Is Influenced by Two Separate Regions on Opposite Sides of the Envelope Protein Receptor Binding Domain
Journal of Virology·2008· 5 citedOpen Access
Increased proinflammatory cytokine and chemokine responses and microglial infection following inoculation with neural stem cells infected with polytropic murine retroviruses
Virology·2006· 15 cited
Role of Low CD4 Levels in the Influence of Human Immunodeficiency Virus Type 1 Envelope V1 and V2 Regions on Entry and Spread in Macrophages
Journal of Virology·2005· 64 citedOpen Access
Separate Sequences in a Murine Retroviral Envelope Protein Mediate Neuropathogenesis by Complementary Mechanisms with Differing Requirements for Tumor Necrosis Factor Alpha
Journal of Virology·2004· 15 citedOpen Access
Human Immunodeficiency Virus Type 1 Envelope-Mediated Neuronal Death: Uncoupling of Viral Replication and Neurotoxicity
Journal of Virology·2003· 47 citedOpen Access
N-terminal Truncation of Prion Protein Affects Both Formation and Conformation of Abnormal Protease-resistant Prion Protein Generatedin Vitro
Journal of Biological Chemistry·2001· 84 citedOpen Access
Species-Independent Inhibition of Abnormal Prion Protein (PrP) Formation by a Peptide Containing a Conserved PrP Sequence
Journal of Virology·1999· 83 citedOpen Access
Neuronal Death Induced by Brain-Derived Human Immunodeficiency Virus Type 1 Envelope Genes Differs between Demented and Nondemented AIDS Patients
Journal of Virology·1998· 173 citedOpen Access
The Cell Tropism of Human Immunodeficiency Virus Type 1 Determines the Kinetics of Plasma Viremia in SCID Mice Reconstituted with Human Peripheral Blood Leukocytes
Journal of Virology·1998· 2 citedOpen Access
The Neuroinvasiveness of a Murine Retrovirus Is Influenced by a Dileucine-Containing Sequence in the Cytoplasmic Tail of Glycosylated Gag
Journal of Virology·1998· 21 citedOpen Access
Effects of CCR5 and CD4 Cell Surface Concentrations on Infections by Macrophagetropic Isolates of Human Immunodeficiency Virus Type 1
Journal of Virology·1998· 1.2k citedOpen Access
The Cell Tropism of Human Immunodeficiency Virus Type 1 Determines the Kinetics of Plasma Viremia in SCID Mice Reconstituted with Human Peripheral Blood Leukocytes
Journal of Virology·1998· 49 citedOpen Access
Selective employment of chemokine receptors as human immunodeficiency virus type 1 coreceptors determined by individual amino acids within the envelope V3 loop
Journal of Virology·1997· 272 citedOpen Access
p24 Antigen Capture Assay for Quantification of Human Immunodeficiency Virus Using Readily Available Inexpensive Reagents
Methods·1997· 152 cited
Mapping of independent V3 envelope determinants of human immunodeficiency virus type 1 macrophage tropism and syncytium formation in lymphocytes
Journal of Virology·1996· 143 citedOpen Access
<i>In Vitro</i> Effects of Anti-HIV Immunotoxins Directed against Multiple Epitopes on HIV Type 1 Envelope Glycoprotein 160
AIDS Research and Human Retroviruses·1996· 33 cited
Sequences regulating tropism of human immunodeficiency virus type 1 for brain capillary endothelial cells map to a unique region on the viral genome
Journal of Virology·1996· 48 citedOpen Access
Multidrug-resistant human immunodeficiency virus type 1 strains resulting from combination antiretroviral therapy
Journal of Virology·1996· 247 citedOpen Access
Human Immunodeficiency Virus Envelope V1 and V2 Regions Influence Replication Efficiency in Macrophages by Affecting Virus Spread
Virology·1995· 157 cited
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Frequent Co-authors

Bruce Chesebro(46), Jane Nishio(21), S Perryman(5), John L. Portis(5), David Kabat(4), Seth H. Pincus(4), Emily J. Platt(3), R S Buller(3), Marc Sitbon(3), Suzette A. Priola(3), Richard Race(2), Marshall E. Bloom(2), William J. Britt(2), Leonard H. Evans(2), M W Cloyd(2), Christopher Power(2), Byron Caughey(2), S F Hayes(2), Masaaki Miyazawa(2), Shawn E. Kuhmann(1)