David Kabat

Oregon Health & Science University — United States

Immunology and Microbiology · Life Sciences

61h-index13.4kcitations166works0.02yr avg
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Research Topics

HIV Research and Treatment(73), Virus-based gene therapy research(52), Immune Cell Function and Interaction(33), RNA and protein synthesis mechanisms(23), HIV/AIDS drug development and treatment(22)

Publications166 total

Movements of HIV-1 genomic RNA-APOBEC3F complexes and PKR reveal cytoplasmic and nuclear PKR defenses and HIV-1 evasion strategies
Virus Research·2015Open Access
Short Communication: HIV-1 Variants That Use Mouse CCR5 Reveal Critical Interactions of gp120's V3 Crown with CCR5 Extracellular Loop 1
AIDS Research and Human Retroviruses·2015· 2 citedOpen Access
RRE-dependent HIV-1 Env RNA effects on Gag protein expression, assembly and release
Virology·2014· 11 citedOpen Access
Reversible and Efficient Activation of HIV-1 Cell Entry by a Tyrosine-Sulfated Peptide Dissects Endocytic Entry and Inhibitor Mechanisms
Journal of Virology·2014· 11 citedOpen Access
Kinetic mechanism for HIV-1 neutralization by antibody 2G12 entails reversible glycan binding that slows cell entry
Proceedings of the National Academy of Sciences·2012· 37 citedOpen Access
Mechanism of HIV-1 Neutralization by an Antibody: Reversible Binding Stalls Entry
Antiviral Research·2011
Rapid Dissociation of HIV-1 from Cultured Cells Severely Limits Infectivity Assays, Causes the Inactivation Ascribed to Entry Inhibitors, and Masks the Inherently High Level of Infectivity of Virions
Journal of Virology·2009· 69 citedOpen Access
Evidence that Ecotropic Murine Leukemia Virus Contamination in TZM-bl Cells Does Not Affect the Outcome of Neutralizing Antibody Assays with Human Immunodeficiency Virus Type 1
Journal of Virology·2009· 234 citedOpen Access
Human Immunodeficiency Virus Type 1 Vif Functionally Interacts with Diverse APOBEC3 Cytidine Deaminases and Moves with Them between Cytoplasmic Sites of mRNA Metabolism
Journal of Virology·2007· 64 citedOpen Access
An Allosteric Rheostat in HIV-1 gp120 Reduces CCR5 Stoichiometry Required for Membrane Fusion and Overcomes Diverse Entry Limitations
Journal of Molecular Biology·2007· 22 citedOpen Access
The role of the N-terminal segment of CCR5 in HIV-1 Env-mediated membrane fusion and the mechanism of virus adaptation to CCR5 lacking this segment
Retrovirology·2007· 15 citedOpen Access
An unprecedented and simple gp120 switch mechanism enables HIV-1 to overcome multiple entry inhibitors and tropism limitations
Retrovirology·2006Open Access
The Anti-HIV-1 Editing Enzyme APOBEC3G Binds HIV-1 RNA and Messenger RNAs That Shuttle between Polysomes and Stress Granules
Journal of Biological Chemistry·2006· 184 citedOpen Access
Kinetic Factors Control Efficiencies of Cell Entry by HIV-1
Retrovirology·2005Open Access
Regulated Production and Anti-HIV Type 1 Activities of Cytidine Deaminases APOBEC3B, 3F, and 3G
AIDS Research and Human Retroviruses·2005· 60 cited
CCR5 N-terminal Region Plays a Critical Role in HIV-1 Inhibition by Toxoplasma gondii-derived Cyclophilin-18
Journal of Biological Chemistry·2005· 14 citedOpen Access
Role of Low CD4 Levels in the Influence of Human Immunodeficiency Virus Type 1 Envelope V1 and V2 Regions on Entry and Spread in Macrophages
Journal of Virology·2005· 64 citedOpen Access
Kinetic Factors Control Efficiencies of Cell Entry, Efficacies of Entry Inhibitors, and Mechanisms of Adaptation of Human Immunodeficiency Virus
Journal of Virology·2005· 109 citedOpen Access
Variants of Human Immunodeficiency Virus Type 1 That Efficiently Use CCR5 Lacking the Tyrosine-Sulfated Amino Terminus Have Adaptive Mutations in gp120, Including Loss of a Functional N-Glycan
Journal of Virology·2005· 27 citedOpen Access
Transcriptional Regulation of APOBEC3G, a Cytidine Deaminase That Hypermutates Human Immunodeficiency Virus
Journal of Biological Chemistry·2004· 77 citedOpen Access
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Frequent Co-authors

Susan L. Kozak(14), Emily J. Platt(7), Mariana Marin(6), Michael P. Kavanaugh(5), Shawn E. Kuhmann(4), Chetankumar S. Tailor(4), K Wehrly(3), Bruce Chesebro(3), Kristine M. Rose(3), Barbara H. Iglewski(3), Navid Madani(3), Ali Nouri(3), Christine A. Kozak(3), Scott M. Schuetze(3), A. Dusty Miller(2), Wei Zhang(2), Dimitri Lavillette(2), Maureen E. Hoatlin(2), R. Walker Paul(2), Corinne C. Sherton(2)