Chandrakala Pidathala

University of Liverpool — United Kingdom

Medicine · Health Sciences

14h-index1.0kcitations27works0.02yr avg
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Research Topics

Malaria Research and Control(7), Computational Drug Discovery Methods(5), HIV/AIDS drug development and treatment(5), Crystallization and Solubility Studies(5), X-ray Diffraction in Crystallography(5)

Publications27 total

Targeting the Ubiquinol-Reduction (Qi) Site of the Mitochondrial Cytochrome bc1 Complex for the Development of Next Generation Quinolone Antimalarials
Biology·2022· 15 citedOpen Access
Crystal structure of bovine cytochrome bc1 in complex with quinolone inhibitor CK-2-68
2020· 1 cited
Combination of Aqueous Extracts of Phyllanthus niruri, Boerhavia diffusa,and Picrorhiza kurroaor Zingiber officinalealone Inhibit Intracellular Inflammatory Signaling Cascade
Journal of Herbal Medicine·2020· 8 cited
A Polyherbal Indian System of Medicine (Ayush) Preparation for Optimization of Glycemic Control in Newly Diagnosed Type 2 Diabetes and Prediabetes; A Multicenter, Randomised, Double-Blind, Placebo- Controlled Trial
2019Open Access
Second-Generation Nitazoxanide Derivatives: Thiazolides are Effective Inhibitors of the Influenza a Virus
Future Medicinal Chemistry·2018· 28 citedOpen Access
A tetraoxane-based antimalarial drug candidate that overcomes PfK13-C580Y dependent artemisinin resistance
Nature Communications·2017· 61 citedOpen Access
Molecular Mechanism of Action of Antimalarial Benzoisothiazolones: Species-Selective Inhibitors of the Plasmodium spp. MEP Pathway enzyme, IspD
Scientific Reports·2016· 24 citedOpen Access
Targeting the Mitochondrial Electron Transport Chain of<i>Plasmodium Falciparum:</i>New Strategies Towards the Development of Improved Antimalarials for the Elimination Era
Future Medicinal Chemistry·2013· 66 cited
CCDC 833897: Experimental Crystal Structure Determination
The Cambridge Structural Database·2013Open Access
CCDC 833920: Experimental Crystal Structure Determination
The Cambridge Structural Database·2013Open Access
CCDC 833299: Experimental Crystal Structure Determination
The Cambridge Structural Database·2013Open Access
Generation of quinolone antimalarials targeting the <i>Plasmodium falciparum</i> mitochondrial respiratory chain for the treatment and prophylaxis of malaria
Proceedings of the National Academy of Sciences·2012· 156 cited
Identification of Novel Antimalarial Chemotypes via Chemoinformatic Compound Selection Methods for a High-Throughput Screening Program against the Novel Malarial Target, PfNDH2: Increasing Hit Rate via Virtual Screening Methods
Journal of Medicinal Chemistry·2012· 23 citedOpen Access
Identification, Design and Biological Evaluation of Bisaryl Quinolones Targeting <i>Plasmodium falciparum</i> Type II NADH:Quinone Oxidoreductase (PfNDH2)
Journal of Medicinal Chemistry·2012· 109 citedOpen Access
Identification, Design and Biological Evaluation of Heterocyclic Quinolones Targeting <i>Plasmodium falciparum</i> Type II NADH:Quinone Oxidoreductase (PfNDH2)
Journal of Medicinal Chemistry·2012· 54 citedOpen Access
Thiazolides as Novel Antiviral Agents. 2. Inhibition of Hepatitis C Virus Replication
Journal of Medicinal Chemistry·2011· 47 cited
Thiazolides as Novel Antiviral Agents. 1. Inhibition of Hepatitis B Virus Replication
Journal of Medicinal Chemistry·2011· 78 cited
CCDC 708552: Experimental Crystal Structure Determination
The Cambridge Structural Database·2010Open Access
CCDC 708551: Experimental Crystal Structure Determination
The Cambridge Structural Database·2010Open Access
ChemInform Abstract: Syntheses and Structures of Anomeric Quaternary Ammonium β‐Glucosides and Comments on the Anomeric C—N Bonds Lengths.
ChemInform·2009
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Frequent Co-authors

Neil G. Berry(12), Giancarlo A. Biagini(11), Stephen A. Ward(10), Gemma L. Nixon(9), Alison E. Shone(8), Raman Sharma(8), Paul M. O’Neill(8), Andrew V. Stachulski(8), Ashley J. Warman(7), Peter Gibbons(7), Alison Mbekeani(7), Paul A. Stocks(7), Richard K. Amewu(6), Bénédicte Pacorel(6), Sitthivut Charoensutthivarakul(6), Linh Hoang(5), Nicola Vignola(5), Benjamin List(5), Nicholas Fisher(5), Suet C. Leung(5)