Nicholas A. Vitanza

Seattle Children's Hospital — United States

Medicine · Health Sciences

30h-index4.0kcitations191works5.12yr avg
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Research Topics

Glioma Diagnosis and Treatment(123), CAR-T cell therapy research(51), Neuroblastoma Research and Treatments(36), Cancer, Hypoxia, and Metabolism(15), Histone Deacetylase Inhibitors Research(14)

Publications188 total

Preclinical efficacy of combinatorial B7-H3 CAR T cells and ONC206 against diffuse intrinsic pontine glioma
Neuro-Oncology·2026· 1 cited
A Cavernous Sinus Meningioma in a Child with Progressive Bilateral Visual Loss Ultimately Attributed to Unsuspected Optic Nerve Sheath Meningiomas
Case Reports in Ophthalmology·2025Open Access
Supplementary Data from ONC201 in Combination with Paxalisib for the Treatment of H3K27-Altered Diffuse Midline Glioma
2025Open Access
Supplementary Data from ONC201 in Combination with Paxalisib for the Treatment of H3K27-Altered Diffuse Midline Glioma
2025Open Access
Engineered CXCR3-A expression enhances B7-H3-targeting CAR T cell migration and efficacy against diffuse intrinsic pontine glioma
Nature Communications·2025· 2 citedOpen Access
DDDR-38. Leveraging the immunomodulatory effects of dordaviprone (ONC201) to induce long-term survival response in diffuse midline glioma patients and models
Neuro-Oncology·2025Open Access
CTIM-38. PIONEERING QUAD-TARGETING CAR T CELL THERAPY IN PEDIATRIC CNS TUMORS – ANALYSIS FROM THE FIRST-IN-HUMAN PHASE 1 TRIAL BRAINCHILD-04
Neuro-Oncology·2025Open Access
EPCO-11. ENHANCING GENOME ANALYSIS WITH WHOLE PROTEOME PROFILING FOR IMPROVED THERAPEUTIC DECISION MAKING IN DIFFUSE MIDLINE GLIOMA
Neuro-Oncology·2025Open Access
CTIM-03. PROTEIN CHANGES IN SERIAL CSF SAMPLES REFLECT CAR ACTIVITY, TOXICITY AND DISEASE RESPONSE IN PATIENTS WITH DIPG TREATED ON THE BRAINCHILD03 TRIAL
Neuro-Oncology·2025Open Access
Neurotoxicity in central nervous system tumors treated with CAR T cell therapy: a review
Journal of Neuro-Oncology·2025· 1 cited
The DIPG/DMG National Tumor Board: The power of advocacy
Neuro-Oncology Pediatrics·2025Open Access
Preclinical efficacy of combinatorial B7-H3 CAR T cells and ONC206 against diffuse intrinsic pontine glioma
2025Open Access
Tumor inflammation-associated neurotoxicity in children with diffuse intrinsic pontine glioma receiving B7-H3-targeting CAR T cells on BrainChild-03
Neuro-Oncology Practice·2025· 1 cited
Evolving CAR T-Cell Therapy to Overcome the Barriers in Treating Pediatric Central Nervous System Tumors
Cancer Discovery·2025· 4 citedOpen Access
Transient mRNA CAR T cells targeting GD2 provide dose-adjusted efficacy against diffuse midline glioma and high-grade glioma models
Neuro-Oncology·2025· 6 citedOpen Access
Abstract 6400: Preclinical efficacy of combinatorial B7-H3 CAR T cell and ONC206 treatment in DIPG/DMG
Cancer Research·2025
Engineered CXCR3-A expression enhances the trafficking and efficacy of intracerebroventricularly delivered B7-H3-targeting CAR T cells against diffuse intrinsic pontine glioma
2025Open Access
Locoregional infusion of EGFR806-CAR T cells for recurrent or refractory pediatric CNS tumors: Results of the completed BrainChild02 phase 1 clinical trial
Neuro-Oncology·2025· 12 citedOpen Access
Intracerebroventricular B7-H3-targeting CAR T cells for diffuse intrinsic pontine glioma: a phase 1 trial
Nature Medicine·2025· 88 citedOpen Access
Translational advancement of immunotherapeutics against pediatric central nervous system tumors
Advances in cancer research·2025
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Frequent Co-authors

Jason N. Wright(10), Matthew D. Dun(10), Michael C. Jensen(9), Julie R. Park(9), Samuel Cheshier(9), Kristen W. Yeom(9), Carl Koschmann(9), Ashley Wilson(8), Navin Pinto(8), Rebecca Gardner(8), Sarah Leary(8), Gerald A. Grant(8), Michelle Han(8), Robert M. Lober(8), Chang Yueh Ho(8), Stephanie Rawlings-Rhea(7), Kristy Seidel(7), Catherine M. Albert(7), Juliane Gust(7), Jeffrey G. Ojemann(7)