John Tazelaar

Biochemistry, Genetics and Molecular Biology · Life Sciences

23h-index3.0kcitations37works0.02yr avg
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Research Topics

Virus-based gene therapy research(20), CAR-T cell therapy research(8), Viral Infectious Diseases and Gene Expression in Insects(7), Respiratory Support and Mechanisms(4), Immunotherapy and Immune Responses(4)

Publications37 total

Prediction of MLH1 and MSH2 Mutations in Lynch Syndrome
JAMA·2006· 191 citedOpen Access
Large rearrangement analysis of <i>MLH1</i> and <i>MSH2</i> in patients undergoing clinical HNPCC testing
Journal of Clinical Oncology·2005
Genetic testing in chronic pancreatitis
Expert Review of Molecular Diagnostics·2003· 1 cited
Regulated expression of erythropoietin from an AAV vector safely improves the anemia of β-thalassemia in a mouse model
Molecular Therapy·2003· 54 citedOpen Access
Adenoviral transfer of HSP-70 into pulmonary epithelium ameliorates experimental acute respiratory distress syndrome
Journal of Clinical Investigation·2002· 108 cited
Adenoviral transfer of HSP-70 into pulmonary epithelium ameliorates experimental acute respiratory distress syndrome
Journal of Clinical Investigation·2002· 124 citedOpen Access
Adenoviral transfer of HSP-70 into pulmonary epithelium ameliorates experimental acute respiratory distress syndrome
Journal of Clinical Investigation·2002· 13 cited
Preexisting Immunity to Adenovirus in Rhesus Monkeys Fails To Prevent Vector-Induced Toxicity
Journal of Virology·2002· 78 citedOpen Access
ENHANCED ADENOVIRAL-MEDIATED PULMONARY EXPRESSION OF HEAT SHOCK PROTEIN-70 (HSP-70) AFTER CECAL LIGATION DOUBLE PUNCTURE (2CLP) LIMITS NF-κB ACTIVATION.
Shock·2002· 1 cited
A Pilot Study of <i>In Vivo</i> Liver-Directed Gene Transfer with an Adenoviral Vector in Partial Ornithine Transcarbamylase Deficiency
Human Gene Therapy·2002· 350 cited
Adenoviral Vector Transfection into the Pulmonary Epithelium after Cecal Ligation and Puncture in Rats
Anesthesiology·2001· 29 citedOpen Access
Adenoviral Transfer of Heat Shock Protein 70 (HSP-70) into Pulmonary Epithelium Improves Histology and Outcome in Experimental Acute Respiratory Distress Syndrome (ARDS) 
Anesthesiology·2001Open Access
Intra-arterial Delivery of a Recombinant Adenovirus Does Not Increase Gene Transfer to Tumor Cells in a Rat Model of Metastatic Colorectal Carcinoma
Molecular Therapy·2001· 19 citedOpen Access
Systemic IFN-β gene therapy results in long-term survival in mice with established colorectal liver metastases
Journal of Clinical Investigation·2001· 47 citedOpen Access
ADENOVIRAL TRANSFER OF HEAT SHOCK PROTEIN 70 (HSP-70) INTO PULMONARY EPITHELIUM IMPROVES HISTOLOGY AND OUTCOME IN EXPERIMENTAL ARDS
Shock·2001
Acute Cytokine Response to Systemic Adenoviral Vectors in Mice Is Mediated by Dendritic Cells and Macrophages
Molecular Therapy·2001· 377 cited
Activation of Innate Immunity in Nonhuman Primates Following Intraportal Administration of Adenoviral Vectors
Molecular Therapy·2001· 339 citedOpen Access
Selective Repopulation of Normal Mouse Liver by Hepatocytes Transduced <i>in Vivo</i> with Recombinant Adeno-Associated Virus
Human Gene Therapy·2001· 22 cited
Prolonged Correction of Hyperlipidemia in Mice with Familial Hypercholesterolemia Using an Adeno-Associated Viral Vector Expressing Very-Low-Density Lipoprotein Receptor
Molecular Therapy·2000· 65 citedOpen Access
In Vivo Selection of Hepatocytes Transduced with Adeno-Associated Viral Vectors
Molecular Therapy·2000· 35 citedOpen Access
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Frequent Co-authors

James M. Wilson(19), Narendra Chirmule(11), Yoram Weiss(10), Clifford S. Deutschman(9), Guangping Gao(8), Joseph V. Hughes(7), Steven E. Raper(5), Nichelle Raj(5), Albert D. Moscioni(4), Beth Gehan(4), Yi Zhang(3), Kathleen J. Propert(3), Michael A. Schnell(3), Alina Maloyan(3), Ruth Qian(2), Susan Magosin(2), Shu‐Jen Chen(2), Andrei N. Varnavski(2), Thomas Scholl(2), Lynn Anne Burbidge(2)