Hamsell M. Alvarez

University of Calgary — Canada

Medicine · Health Sciences

9h-index560citations43works0.02yr avg
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Research Topics

Monoclonal and Polyclonal Antibodies Research(19), Cancer Cells and Metastasis(9), Immunotherapy and Immune Responses(9), Mass Spectrometry Techniques and Applications(8), Crystallization and Solubility Studies(8)

Publications43 total

Abstract LB134: Pre-clinical development of a masked tumor activated nectin-4 conditional IL-15 immuno-cytokine (ABBV-622)
Cancer Research·2025
Variability of Valley Floor Widths in a Mountain Landscape, Canadian Rockies
2025Open Access
Table S1 from Epitope and Fc-Mediated Cross-linking, but Not High Affinity, Are Critical for Antitumor Activity of CD137 Agonist Antibody with Reduced Liver Toxicity
2023Open Access
Data from Epitope and Fc-Mediated Cross-linking, but Not High Affinity, Are Critical for Antitumor Activity of CD137 Agonist Antibody with Reduced Liver Toxicity
2023Open Access
Figure S5 from Epitope and Fc-Mediated Cross-linking, but Not High Affinity, Are Critical for Antitumor Activity of CD137 Agonist Antibody with Reduced Liver Toxicity
2023Open Access
Figure S3 from Epitope and Fc-Mediated Cross-linking, but Not High Affinity, Are Critical for Antitumor Activity of CD137 Agonist Antibody with Reduced Liver Toxicity
2023Open Access
Figure S5 from Epitope and Fc-Mediated Cross-linking, but Not High Affinity, Are Critical for Antitumor Activity of CD137 Agonist Antibody with Reduced Liver Toxicity
2023Open Access
Figure S2 from Epitope and Fc-Mediated Cross-linking, but Not High Affinity, Are Critical for Antitumor Activity of CD137 Agonist Antibody with Reduced Liver Toxicity
2023Open Access
Figure S4 from Epitope and Fc-Mediated Cross-linking, but Not High Affinity, Are Critical for Antitumor Activity of CD137 Agonist Antibody with Reduced Liver Toxicity
2023Open Access
Figure S1 from Epitope and Fc-Mediated Cross-linking, but Not High Affinity, Are Critical for Antitumor Activity of CD137 Agonist Antibody with Reduced Liver Toxicity
2023Open Access
Table S1 from Epitope and Fc-Mediated Cross-linking, but Not High Affinity, Are Critical for Antitumor Activity of CD137 Agonist Antibody with Reduced Liver Toxicity
2023Open Access
Figure S1 from Epitope and Fc-Mediated Cross-linking, but Not High Affinity, Are Critical for Antitumor Activity of CD137 Agonist Antibody with Reduced Liver Toxicity
2023Open Access
Data from Epitope and Fc-Mediated Cross-linking, but Not High Affinity, Are Critical for Antitumor Activity of CD137 Agonist Antibody with Reduced Liver Toxicity
2023Open Access
Figure S2 from Epitope and Fc-Mediated Cross-linking, but Not High Affinity, Are Critical for Antitumor Activity of CD137 Agonist Antibody with Reduced Liver Toxicity
2023Open Access
Figure S6 from Epitope and Fc-Mediated Cross-linking, but Not High Affinity, Are Critical for Antitumor Activity of CD137 Agonist Antibody with Reduced Liver Toxicity
2023Open Access
Figure S3 from Epitope and Fc-Mediated Cross-linking, but Not High Affinity, Are Critical for Antitumor Activity of CD137 Agonist Antibody with Reduced Liver Toxicity
2023Open Access
Figure S6 from Epitope and Fc-Mediated Cross-linking, but Not High Affinity, Are Critical for Antitumor Activity of CD137 Agonist Antibody with Reduced Liver Toxicity
2023Open Access
Figure S4 from Epitope and Fc-Mediated Cross-linking, but Not High Affinity, Are Critical for Antitumor Activity of CD137 Agonist Antibody with Reduced Liver Toxicity
2023Open Access
An anti-PD-1–GITR-L bispecific agonist induces GITR clustering-mediated T cell activation for cancer immunotherapy
Nature Cancer·2022· 66 citedOpen Access
Abstract 1615: Evaluation of efficacy metrics for in vivo experiments with immuno-oncology therapeutic agents
Cancer Research·2020
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Frequent Co-authors

Melvin Fox(21), Yoshiko Akamatsu(21), Diane Hollenbaugh(20), Sun K. Ho(19), C.M. Forsyth(19), Siu Sze Tan(19), Enrico L. DiGiammarino(19), Josue Samayoa(19), Mien Sho(18), Archana Thakur(18), Mengli Xiong(18), Li Zhou(18), Belinda Cairns(18), David B. Powers(18), Zhenghai Xu(17), Debra T. Chao(17), Vivian Zhao(16), Joseph M. Tanski(8), Mariusz Krawiec(6), D. Rabinovich(6)