John H. Dodd

Biochemistry, Genetics and Molecular Biology · Life Sciences

28h-index2.1kcitations90works0.02yr avg
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Research Topics

Melanoma and MAPK Pathways(23), Synthesis and biological activity(15), Cytokine Signaling Pathways and Interactions(10), Computational Drug Discovery Methods(9), melanin and skin pigmentation(7)

Publications90 total

A NEW APPROACH FOR TREATMENT OF ULCERATIVE COLITIS: A MELANOCORTIN RECEPTOR AGONIST PL8177
Gastroenterology·2024Open Access
A NEW APPROACH FOR TREATMENT OF ULCERATIVE COLITIS: A MELANOCORTIN RECEPTOR AGONIST PL8177
Inflammatory Bowel Diseases·2024Open Access
S1014 Cellular and Molecular Impact of the Melanocortin Receptor Agonist PL8177 in Dextran Sulfate Sodium-Induced Colitis in Rats
The American Journal of Gastroenterology·2023
Sa1222 EFFICACY OF THE MELANOCORTIN RECEPTOR AGONIST PL8177 AS A POTENTIAL THERAPY FOR GASTROINTESTINAL (GI) INFLAMMATORY DISEASES
Gastroenterology·2023
A novel oral formulation of the melanocortin-1 receptor agonist PL8177 resolves inflammation in preclinical studies of inflammatory bowel disease and is gut restricted in rats, dogs, and humans
Frontiers in Immunology·2023· 12 citedOpen Access
Pro-resolving and anti-arthritic properties of the MC1 selective agonist PL8177
Frontiers in Immunology·2022· 8 citedOpen Access
CELLULAR AND MOLECULAR IMPACT OF THE MELANOCORTIN RECEPTOR AGONIST PL8177 IN DEXTRAN SODIUM SULFATE (DSS)-INDUCED COLITIS IN RATS
Inflammatory Bowel Diseases·2022Open Access
CELLULAR AND MOLECULAR IMPACT OF THE MELANOCORTIN RECEPTOR AGONIST PL8177 IN DEXTRAN SODIUM SULFATE (DSS)-INDUCED COLITIS IN RATS
Gastroenterology·2022
Effectiveness of a Novel ω-3 Krill Oil Agent in Patients With Severe Hypertriglyceridemia
JAMA Network Open·2022· 22 citedOpen Access
Pharmacokinetics of the Melanocortin Type 1 Receptor Agonist PL8177 After Subcutaneous Administration
Drugs in R&D·2021· 4 citedOpen Access
Efficacy and Safety of the Melanocortin Agonist PL9643 in a Phase 2 Study of Subjects With Dry Eye Disease
2021· 3 cited
Protective Effects of 2 Melanocortin Agonists Delivered by Intravitreal Injection in Mouse Models of Retinopathy
Investigative Ophthalmology & Visual Science·2021Open Access
Fr486 ORAL ADMINISTRATION OF THE MELANOCORTIN-1 RECEPTOR AGONIST PL8177 IN A RAT MODEL OF COLITIS
Gastroenterology·2021· 1 cited
Fr487 PHARMACOKINETIC ANALYSIS IN RATS AND DOGS AFTER ORAL DOSING OF MELANOCORTIN-1 RECEPTOR AGONIST PL8177
Gastroenterology·2021
Probing the Role of Melanocortin Type 1 Receptor Agonists in Diverse Immunological Diseases
Frontiers in Pharmacology·2019· 36 citedOpen Access
Transport, receipt and propagation of invitro sweet potato plants
2016
Discovery of ((4-(5-(Cyclopropylcarbamoyl)-2-methylphenylamino)-5-methylpyrrolo[1,2-<i>f</i>][1,2,4]triazine-6-carbonyl)(propyl)carbamoyloxy)methyl-2-(4-(phosphonooxy)phenyl)acetate (BMS-751324), a Clinical Prodrug of p38α MAP Kinase Inhibitor
Journal of Medicinal Chemistry·2015· 9 cited
Discovery of potent and selective nonsteroidal indazolyl amide glucocorticoid receptor agonists
Bioorganic & Medicinal Chemistry Letters·2013· 13 citedOpen Access
Synthesis and structure–activity relationships of novel indazolyl glucocorticoid receptor partial agonists
Bioorganic & Medicinal Chemistry Letters·2013· 10 citedOpen Access
The identification of novel p38α isoform selective kinase inhibitors having an unprecedented p38α binding mode
Bioorganic & Medicinal Chemistry Letters·2013· 15 citedOpen Access
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Frequent Co-authors

Joel C. Barrish(30), Arthur M. Doweyko(19), Kim W. McIntyre(18), Murray McKinnon(18), Katerina Leftheris(16), Gary L. Schieven(15), David J. Shuster(13), Kathleen M. Gillooly(13), Sidney Pitt(13), John S. Sack(12), Hongjian Zhang(10), Alaric J. Dyckman(10), Punit H. Marathe(9), Stephen T. Wrobleski(9), Ding Ren Shen(9), Rosemary Zhang(9), Susan E. Kiefer(9), Kevin Kish(9), Jagabandhu Das(8), Chunjian Liu(8)