Aude G. Chapuis

University of Washington — United States

Medicine · Health Sciences

30h-index4.6kcitations186works2.82yr avg
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Research Topics

CAR-T cell therapy research(110), Immunotherapy and Immune Responses(36), Polyomavirus and related diseases(30), Virus-based gene therapy research(21), Bacteriophages and microbial interactions(20)

Publications186 total

A CD8αβ co-receptor modified to contain an intracellular CD28 signaling tail enhances TCR-engineered T cell function independent of solid-tumor-associated co-stimulatory ligands
Nature Communications·2026Open Access
Intrathecal rituximab for the treatment of Epstein–Barr virus-associated encephalitis
Frontiers in Immunology·2025Open Access
High-dose anakinra to treat refractory immune effector cell-associated neurotoxicity syndrome in CAR T-cell therapy recipients
Blood·2025
Succinate-SUCNR1 signaling drives Treg-mediated suppression in the solid tumor 4795
The Journal of Immunology·2025Open Access
608 A phase I clinical trial of a personalized neoantigen vaccine in PD-1 inhibitor refractory metastatic melanoma
Regular and Young Investigator Award Abstracts·2025Open Access
344 Safety and efficacy of targeting the p14ARF tumor suppressor using TCR T-cell therapy
Regular and Young Investigator Award Abstracts·2025Open Access
345 Discovery and characterization of human T cell receptors that recognize tumor-associated antigens derived from tumor suppressors p16INK4A and p14ARF
Regular and Young Investigator Award Abstracts·2025Open Access
602 A personalized neoantigen vaccine induces anti-tumor T cell responses in patients with PD-1/PD-L1 inhibitor refractory metastatic melanoma
Regular and Young Investigator Award Abstracts·2025Open Access
Collagen-binding IL-12-armoured STEAP1 CAR-T cells reduce toxicity and treat prostate cancer in mouse models
Nature Biomedical Engineering·2025· 5 citedOpen Access
Impact of Gamma-Secretase Inhibition on Outcomes Following BCMA CAR-T Therapy in Multiple Myeloma: A Comparison of Two Phase 1 Trials
Transplantation and Cellular Therapy·2025· 1 cited
A phase I/II trial of WT1-specific TCR gene therapy for patients with acute myeloid leukemia and active disease post-allogeneic hematopoietic cell transplantation: skewing towards NK-like phenotype impairs T cell function and persistence
Nature Communications·2025· 4 citedOpen Access
139 | ENHANCED CAR T‐CELL EXPANSION AND DURABLE COMPLETE RESPONSES WITH NKTR‐255 PLUS LISOCABTAGENE MARALEUCEL IN RELAPSED/REFRACTORY LARGE B‐CELL LYMPHOMA
Hematological Oncology·2025· 1 citedOpen Access
A CD8αβ co-receptor modified to contain an intracellular CD28 signaling tail enhances TCR-engineered T cell function independent of solid-tumor-associated co-stimulatory ligands
2025Open Access
<i>Collagen-binding IL-12 expressing</i> STEAP1 CAR-T cells reduce toxicity and eradicate mouse prostate cancer in combination with checkpoint inhibitors
2025· 1 citedOpen Access
Real-world comparison of lisocabtagene maraleucel and axicabtagene ciloleucel in large B-cell lymphoma: an inverse probability of treatment weighting analysis with 3-year follow up
Haematologica·2025· 3 citedOpen Access
Abstract B060: Elevated tumor secreted metabolites direct immunosuppression by promoting Treg proliferation in the solid tumor
Cancer Immunology Research·2025
Phase 2 Trial of SC Versus IV Anakinra to Prevent CRS and Neurotoxicity in LBCL Patients Receiving Lisocabtagene Maraleucel: Final Analysis and Comparison to Historical Control
Transplantation and Cellular Therapy·2025
Autoimmune Outcomes in Patients with Concurrent Autoimmune Disease Receiving CD19- or BCMA-Targeted CAR T-Cell Therapy for Lymphoma or Multiple Myeloma
Transplantation and Cellular Therapy·2025
Phase I study of autologous CD8+ and CD4+ transgenic T cells expressing high-affinity KRAS G12V mutation-specific T cell receptors (FH-A11KRASG12V-TCR) in patients with metastatic pancreatic, colorectal, and non-small cell lung cancers with KRAS G12V mutations.
Journal of Clinical Oncology·2025· 1 cited
Acute Myeloid Leukemia Skews Therapeutic WT1-specific CD8 TCR-T Cells Towards an NK-like Phenotype that Compromises Function and Persistence
2024Open Access
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Frequent Co-authors

Philip D. Greenberg(14), Kelly G. Paulson(13), Brian G. Till(13), David G. Maloney(13), Cameron J. Turtle(13), Jordan Gauthier(12), Mazyar Shadman(12), Stanley R. Riddell(12), Ryan D. Cassaday(11), Shailender Bhatia(10), Hans‐Peter Kiem(10), Felecia Wagener(9), Paul Nghiem(8), Alexandre V. Hirayama(8), Ted Gooley(8), Thomas M. Schmitt(8), Barbara S. Pender(7), Aesha Vakil(7), Merav Bar(7), Cassian Yee(7)