Daniel I. Brierley

University College London — United Kingdom

Medicine · Health Sciences

17h-index2.1kcitations28works13.32yr avg
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Research Topics

Diabetes Treatment and Management(9), Regulation of Appetite and Obesity(9), Receptor Mechanisms and Signaling(9), Neuropeptides and Animal Physiology(6), Cannabis and Cannabinoid Research(5)

Publications28 total

Brainstem GLP-1 neurons modulate physiological satiation and drive sustained weight loss in obese mice
2025
GLP-1 and the Neurobiology of Eating Control: Recent Advances
Endocrinology·2025· 17 citedOpen Access
A neuronal circuit driven by GLP-1 in the olfactory bulb regulates insulin secretion
Nature Communications·2024· 23 citedOpen Access
Obesity medication lorcaserin activates brainstem GLP-1 neurons to reduce food intake and augments GLP-1 receptor agonist induced appetite suppression
Molecular Metabolism·2022· 31 citedOpen Access
Obesity medication lorcaserin requires brainstem GLP-1 neurons to reduce food intake in mice
2022Open Access
Function of the nucleus of the solitary tract in the therapeutic effect of obesity medication lorcaserin
Proceedings of The Nutrition Society·2022Open Access
Brain GLP‐1 and the regulation of food intake: GLP‐1 action in the brain and its implications for GLP‐1 receptor agonists in obesity treatment
British Journal of Pharmacology·2021· 132 citedOpen Access
Reappraising the role of the vagus nerve in GLP‐1‐mediated regulation of eating
British Journal of Pharmacology·2021· 64 citedOpen Access
Central and peripheral GLP-1 systems independently suppress eating
Nature Metabolism·2021· 240 citedOpen Access
Author Correction: Super-resolution microscopy compatible fluorescent probes reveal endogenous glucagon-like peptide-1 receptor distribution and dynamics
UCL Discovery (University College London)·2020Open Access
Author Correction: Super-resolution microscopy compatible fluorescent probes reveal endogenous glucagon-like peptide-1 receptor distribution and dynamics
Nature Communications·2020· 5 citedOpen Access
Central and peripheral GLP-1 systems independently and additively suppress eating
2020· 8 cited
PPG neurons in the nucleus of the solitary tract modulate heart rate but do not mediate GLP-1 receptor agonist-induced tachycardia in mice
Molecular Metabolism·2020· 32 citedOpen Access
Super-resolution microscopy compatible fluorescent probes reveal endogenous glucagon-like peptide-1 receptor distribution and dynamics.
Apollo (University of Cambridge)·2020Open Access
Super-resolution microscopy compatible fluorescent probes reveal endogenous glucagon-like peptide-1 receptor distribution and dynamics
Nature Communications·2020· 140 citedOpen Access
孤束核のプレプログルカゴンニューロンは脳内GLP-1の主要な産生細胞であり,ストレス誘発性の摂食抑制を仲介し,異常な大量摂食を制限する
Diabetes·2019
Chemotherapy‐induced cachexia dysregulates hypothalamic and systemic lipoamines and is attenuated by cannabigerol
Journal of Cachexia Sarcopenia and Muscle·2019· 50 citedOpen Access
Super-resolution microscopy compatible fluorescent probes reveal endogenous glucagon-like peptide-1 receptor distribution and dynamics
Apollo (University of Cambridge)·2019Open Access
Preproglucagon Neurons in the Nucleus of the Solitary Tract Are the Main Source of Brain GLP-1, Mediate Stress-Induced Hypophagia, and Limit Unusually Large Intakes of Food
Diabetes·2018· 195 cited
GLP‐1 neurons form a local synaptic circuit within the rodent nucleus of the solitary tract
The Journal of Comparative Neurology·2018· 37 citedOpen Access
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Frequent Co-authors

Stefan Trapp(17), Frank Reimann(12), Marie K. Holt(7), Fiona M. Gribble(6), Johannes Broichhagen(6), David J. Hodson(6), Julia Ast(5), Anastasia Arvaniti(5), Nicholas H. F. Fine(5), Daniela Nasteska(5), Fiona Ashford(5), Zania Stamataki(5), Andrea Bacon(5), Ben Jones(5), Maria Lucey(5), Shugo Sasaki(5), Benoît Hastoy(5), Alejandra Tomás(5), Giuseppe D’Agostino(5), Francis C. Lynn(5)