Niraja Dighe

Singapore General Hospital — Singapore

Biochemistry, Genetics and Molecular Biology · Life Sciences

7h-index489citations18works0.02yr avg
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Research Topics

Virus-based gene therapy research(8), RNA Interference and Gene Delivery(5), CRISPR and Genetic Engineering(5), Mesenchymal stem cell research(3), Acute Myeloid Leukemia Research(3)

Publications18 total

Correction: Bone marrow MSCs in MDS: contribution towards dysfunctional hematopoiesis and potential targets for disease response to hypomethylating therapy
Leukemia·2019· 6 citedOpen Access
Bone marrow MSCs in MDS: contribution towards dysfunctional hematopoiesis and potential targets for disease response to hypomethylating therapy
Leukemia·2018· 70 citedOpen Access
A comparison of intrauterine hemopoietic cell transplantation and lentiviral gene transfer for the correction of severe β-thalassemia in a HbbTh3/+ murine model
Experimental Hematology·2018· 15 citedOpen Access
Ex Vivo Expansion of SCID-Repopulating CD34+CD90+CD49f+Hematopoietic Stem & Progenitor Cells From Non-Enriched Human Umbilical Cord Blood with Novel Azole-Based Small Molecules
Biology of Blood and Marrow Transplantation·2018· 1 citedOpen Access
Ex Vivo Expansion of CD34+CD90+CD49f+ Hematopoietic Stem and Progenitor Cells from Non-Enriched Umbilical Cord Blood with Azole Compounds
Stem Cells Translational Medicine·2018· 27 citedOpen Access
Manipulating Osteogenic/Adipogenic Balance in Mesenchymal Stromal Cells (MSCs) for Hematopoietic Applications
Blood·2017
Evaluating the Mesenchymal Stromal Cell (MSCs) Contribution in Pre-Leukemic Myelodysplastic Syndromes in Different Patient Risk Groups
Blood·2017
Mechanism of Action of Azacytidine in Myelodysplastic Syndromes (MDS)
Blood·2016
251. Intrauterine Haemopoietic Stem Cell Therapy Followed By Postnatal Cell Re-Infusion To Enhance Engraftment in a Murine Thalassaemia Model
Molecular Therapy·2015Open Access
Long-Term Reproducible Expression in Human Fetal Liver Hematopoietic Stem Cells with a UCOE-Based Lentiviral Vector
PLoS ONE·2014· 24 citedOpen Access
The Fetal Mouse Is a Sensitive Genotoxicity Model That Exposes Lentiviral-associated Mutagenesis Resulting in Liver Oncogenesis
Molecular Therapy·2013· 23 citedOpen Access
Stable Human FIX Expression After 0.9G Intrauterine Gene Transfer of Self-complementary Adeno-associated Viral Vector 5 and 8 in Macaques
Molecular Therapy·2011· 73 citedOpen Access
Late-Gestation Intravascular Delivery of Self-Complementary AAV Leads to Sustained Transgene Expression with the Possibility of Vector Integration Events in the Liver
UCL Discovery (University College London)·2010
Oncogenesis following delivery of a nonprimate lentiviral gene therapy vector to fetal and neonatal mice (vol 12, pg 763, 2005)
UCL Discovery (University College London)·2006· 3 cited
827. Oncogenesis Following Delivery of Lentiviral Vectors to Fetal and Neonatal Mice
Molecular Therapy·2006Open Access
Corrigendum to “Oncogenesis Following Delivery of a Nonprimate Lentiviral Gene Therapy Vector to Fetal and Neonatal Mice”
Molecular Therapy·2005· 3 citedOpen Access
Oncogenesis Following Delivery of a Nonprimate Lentiviral Gene Therapy Vector to Fetal and Neonatal Mice
Molecular Therapy·2005· 244 citedOpen Access
Oncogenesis following delivery of a nonprimate lentiviral gene therapy vector to fetal and neonatal mice
UCL Discovery (University College London)·2005

Frequent Co-authors

Michael Themis(10), Simon N. Waddington(9), Manfred Schmidt(7), Suzanne M. K. Buckley(7), Zhiyong Poon(7), William Ying Khee Hwang(7), Christof von Kalle(6), Faisal A. Al-Allaf(6), Brian Bigger(6), Adrian J. Thrasher(6), Charles Coutelle(6), Xiubo Fan(6), Sudipto Bari(6), Megha Nivsarkar(5), Ajay Mistry(5), Citra Nurfarah Zaini Mattar(5), Mahesh Choolani(5), Yoahe Wang(4), Lisa G. Gregory(4), Maxine V. Holder(4)