Peter Karran

The Francis Crick Institute — United Kingdom

Biochemistry, Genetics and Molecular Biology · Life Sciences

57h-index10.8kcitations161works0.02yr avg
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Research Topics

DNA Repair Mechanisms(98), Genetic factors in colorectal cancer(41), DNA and Nucleic Acid Chemistry(29), Carcinogens and Genotoxicity Assessment(25), Cancer Genomics and Diagnostics(24)

Publications161 total

Mutation and aging: news from the pool
Aging·2023· 2 citedOpen Access
Data from Oxidative Stress–Induced Protein Damage Inhibits DNA Repair and Determines Mutation Risk and Therapeutic Efficacy
2023Open Access
Supplementary figures 1-5 from Oxidative Stress–Induced Protein Damage Inhibits DNA Repair and Determines Mutation Risk and Therapeutic Efficacy
2023Open Access
Data from Oxidative Stress–Induced Protein Damage Inhibits DNA Repair and Determines Mutation Risk and Therapeutic Efficacy
2023Open Access
Supplementary figures 1-5 from Oxidative Stress–Induced Protein Damage Inhibits DNA Repair and Determines Mutation Risk and Therapeutic Efficacy
2023Open Access
Data from Oxidation-Mediated DNA Cross-Linking Contributes to the Toxicity of 6-Thioguanine in Human Cells
2023Open Access
Supplementary Figure 1 from Oxidation-Mediated DNA Cross-Linking Contributes to the Toxicity of 6-Thioguanine in Human Cells
2023Open Access
Data from Oxidation-Mediated DNA Cross-Linking Contributes to the Toxicity of 6-Thioguanine in Human Cells
2023Open Access
Supplementary Figure 1 from Oxidation-Mediated DNA Cross-Linking Contributes to the Toxicity of 6-Thioguanine in Human Cells
2023Open Access
Young transgenic hMTH1 mice are protected against dietary fat‐induced metabolic stress—implications for enhanced longevity
Aging Cell·2022· 6 citedOpen Access
Oxidative stress induced by UVA photoactivation of the tryptophan UVB photoproduct 6-formylindolo[3,2-b]carbazole (FICZ) inhibits nucleotide excision repair in human cells
Scientific Reports·2017· 43 citedOpen Access
Oxidatively-generated damage to DNA and proteins mediated by photosensitized UVA
Free Radical Biology and Medicine·2016· 124 citedOpen Access
Photosensitized UVA-Induced Cross-Linking between Human DNA Repair and Replication Proteins and DNA Revealed by Proteomic Analysis
Journal of Proteome Research·2016· 17 citedOpen Access
Protein oxidation, UVA and human DNA repair
DNA repair·2016· 151 citedOpen Access
Oxidative Stress–Induced Protein Damage Inhibits DNA Repair and Determines Mutation Risk and Therapeutic Efficacy
Molecular Cancer Research·2016· 84 citedOpen Access
Oxidative Damage to RPA Limits the Nucleotide Excision Repair Capacity of Human Cells
Journal of Investigative Dermatology·2015· 61 citedOpen Access
UVA photoactivation of DNA containing halogenated thiopyrimidines induces cytotoxic DNA lesions
Journal of Photochemistry and Photobiology B Biology·2015· 23 citedOpen Access
MUTYH mediates the toxicity of combined DNA 6-thioguanine and UVA radiation
Oncotarget·2014· 13 citedOpen Access
DNA repair inhibition by UVA photoactivated fluoroquinolones and vemurafenib
Nucleic Acids Research·2014· 24 citedOpen Access
5-Iodo-4-thio-2′-deoxyuridine: Synthesis, Structure, and Cytotoxic Activity
Chemistry Letters·2014· 9 cited
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Frequent Co-authors

Margherita Bignami(9), Tomas Lindahl(8), Conal M. Perrett(5), Yao−Zhong Xu(5), Gabriele Aquilina(5), Peter Macpherson(5), Peter O’Donovan(4), Catherine Harwood(4), Beatriz Montaner(3), N. R. Attard(3), P Branch(3), Richard Hampson(3), Reto Brem(3), Xiaohong Zhang(2), Susan L. Walker(2), Paolo Degan(2), Eugenia Dogliotti(2), Jane Warwick(2), J.M. McGregor(2), Paola Fortini(2)