Daniel J. Sprague

Medical University of South Carolina — United States

Immunology and Microbiology · Life Sciences

11h-index611citations45works2.82yr avg
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Research Topics

Parasites and Host Interactions(9), Protein Degradation and Inhibitors(8), Parasite Biology and Host Interactions(7), Multiple Myeloma Research and Treatments(6), Asymmetric Synthesis and Catalysis(5)

Publications45 total

On the Discorhabdins Leading to the Aleutianamine Ring System: A One‐Step in Situ Transformation Characterized Through Computational and Experimental Studies and Its Implications on Biosynthesis, Synthesis, and Pharmacology
Angewandte Chemie International Edition·2026Open Access
On the Discorhabdins Leading to the Aleutianamine Ring System: A One‐Step in Situ Transformation Characterized Through Computational and Experimental Studies and Its Implications on Biosynthesis, Synthesis, and Pharmacology
Angewandte Chemie·2026· 1 citedOpen Access
Meclonazepam sensitivity of parasitic flatworms correlates with TRPMMCLZ sensitivity to meclonazepam.
Open Access CRIS of the University of Bern·2026Open Access
Meclonazepam sensitivity of parasitic flatworms correlates with TRPMMCLZ sensitivity to meclonazepam
International Journal for Parasitology Drugs and Drug Resistance·2026Open Access
Aleutianamine B, A Novel Chiral Sulfoxide Isolated from <i>Latrunculia</i> spp. and Generated via Semi-Synthesis, Exhibits Selectivity for Ovarian Cancer Cells
Journal of Natural Products·2025· 1 cited
The Molecular Drug Target of Praziquantel
2025Open Access
Target-Based Design of Praziquantel Analogs at Cestode TRPM<sub>PZQ</sub>
ACS Infectious Diseases·2025· 1 citedOpen Access
Abstract 1594 BRD9 functions as a methylarginine reader to regulate AKT-EZH2 signaling
Journal of Biological Chemistry·2025Open Access
BRD9 functions as a methylarginine reader to regulate AKT-EZH2 signaling
Science Advances·2025· 1 citedOpen Access
A novel HLA Class II presentation prediction algorithm deciphers immunogenic CD4 epitopes specific to KRAS G12C
2024Open Access
The TRIM33 Bromodomain Recognizes Histone Lysine Lactylation
ACS Chemical Biology·2024· 24 citedOpen Access
Functional classification of long non-coding RNAs by k-mer content
UNC Libraries·2024Open Access
Target-based discovery of a broad-spectrum flukicide
Nature Structural & Molecular Biology·2024· 9 citedOpen Access
Zinc-chelating BET bromodomain inhibitors equally target islet endocrine cell types
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology·2024· 1 citedOpen Access
Abstract 904: AI platform provides an EDGE and enables state-of-the-art identification of peptide-HLAs for the development of T cell inducing vaccines
Cancer Research·2024· 2 cited
TRP drop, TRP drop: a steady patter of anti-schistosomal target illumination
Frontiers in Parasitology·2024· 5 citedOpen Access
The anthelmintic meclonazepam activates a schistosome transient receptor potential channel
Journal of Biological Chemistry·2023· 13 citedOpen Access
The Anthelmintic Activity of Praziquantel Analogs Correlates with Structure–Activity Relationships at TRPM<sub>PZQ</sub> Orthologs
ACS Medicinal Chemistry Letters·2023· 7 citedOpen Access
Target-based discovery of a broad spectrum flukicide
2023· 6 citedOpen Access
Mu-opioid receptor selective superagonists produce prolonged respiratory depression
iScience·2023· 42 citedOpen Access
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Frequent Co-authors

Jonathan S. Marchant(10), Brian C. Smith(9), Claudia M. Rohr(9), Sang-Kyu Park(8), Jessime M. Kirk(5), J. Mauro Calabrese(5), Michael D. Olp(4), Sarah L. Wynia‐Smith(4), Marc Kaethner(4), Stefan G. Kathman(3), Ziyang Xu(3), Raymundo Nuñez(3), Jeffrey N. Johnston(3), Maurice J. Narcis(3), Burjor Captain(3), Norito Takenaka(3), Evgeny G. Chulkov(3), Britta Lundström‐Stadelmann(3), Joshua S. Klein(3), Monica Lane(3)