Jean‐Philippe Pin

Centre National de la Recherche Scientifique — France

Biochemistry, Genetics and Molecular Biology · Life Sciences

93h-index34.5kcitations440works3.12yr avg
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Research Topics

Receptor Mechanisms and Signaling(262), Neuroscience and Neuropharmacology Research(259), Neuropeptides and Animal Physiology(79), Photoreceptor and optogenetics research(48), Nicotinic Acetylcholine Receptors Study(43)

Publications435 total

Multi-faceted roles of β-arrestins in G protein-coupled receptor endocytosis
Nature Communications·2025· 1 citedOpen Access
Nanobodies: a new paradigm for brain disorder therapies
Trends in Pharmacological Sciences·2025· 1 citedOpen Access
Endothelin Signaling via EDNRB receptor Reduces Proliferation and Promotes Proneural-to-Mesenchymal Transition in Gliomas
2025· 1 citedOpen Access
Class A Orphans in GtoPdb v.2025.3
IUPHAR/BPS Guide to Pharmacology CITE·2025Open Access
GABA<sub>B</sub> receptors in GtoPdb v.2025.3
IUPHAR/BPS Guide to Pharmacology CITE·2025Open Access
Metabotropic glutamate receptors in GtoPdb v.2025.3
IUPHAR/BPS Guide to Pharmacology CITE·2025Open Access
Structural characterization of five functional states of metabotropic glutamate receptor 8
Molecular Cell·2025· 2 citedOpen Access
Non-canonical internalization mechanisms of mGlu receptors
Cell Reports·2025· 2 citedOpen Access
Nanobody therapy rescues behavioural deficits of NMDA receptor hypofunction
Nature·2025· 8 citedOpen Access
Class A Orphans in GtoPdb v.2025.2
IUPHAR/BPS Guide to Pharmacology CITE·2025Open Access
Triple Labeling Resolves a GPCR Intermediate State by Using Three-Color Single Molecule FRET
Journal of the American Chemical Society·2025· 4 citedOpen Access
A modular click ligand-directed approach to label endogenous dopamine D1 receptors in live cells
Communications Chemistry·2025· 3 citedOpen Access
Class A Orphans in GtoPdb v.2025.1
IUPHAR/BPS Guide to Pharmacology CITE·2025Open Access
Non-canonical internalization mechanisms of mGlu receptors
2025· 1 citedOpen Access
BPS2025 - Site-specific triple labeling and three-color single-molecule FRET resolve a conformational intermediate during the activation of a G-protein-coupled receptor
Biophysical Journal·2025
Structural basis of orientated asymmetry in a mGlu heterodimer
Nature Communications·2024· 11 citedOpen Access
Triple labeling resolves a GPCR intermediate state by 3-color single molecule FRET
2024· 1 citedOpen Access
Heterodimers Revolutionize the Field of Metabotropic Glutamate Receptors
Neuroscience·2024· 14 citedOpen Access
Photoswitchable positive allosteric modulators of metabotropic glutamate receptor 4 to improve selectivity
iScience·2024· 4 citedOpen Access
Novel Inhibitory Site Revealed by <b>XAP044</b> Mode of Action on the Metabotropic Glutamate 7 Receptor Venus Flytrap Domain
Journal of Medicinal Chemistry·2024· 4 citedOpen Access
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Frequent Co-authors

Joël Bockaert(13), Laurent Prézeau(13), Richard R. Neubig(6), Michael Spedding(6), Isabelle Brabet(5), Francine Acher(4), Tom I. Bonner(4), Anthony P. Davenport(4), Anthony J. Harmar(4), Philippe Rondard(4), Rainer Kühn(4), Bernhard Bettler(4), Julie Kniazeff(4), Cyril Goudet(4), Michèle Sebben(3), Steven M. Foord(3), Lakshmi A. Devi(3), Martin J. Lohse(3), Graeme Milligan(3), Thierry Durroux(3)